Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Asuman Mutlu"'
Autor:
Valery Leytin, Asuman Mutlu, Sergiy Mykhaylov, David J. Allen, Armen V. Gyulkhandanyan, John Freedman
Publikováno v:
Haematologica, Vol 94, Iss 12 (2009)
Externí odkaz:
https://doaj.org/article/e9d5f5848f88457c905c917949c09ab9
Publikováno v:
British Journal of Haematology. 163:377-384
Summary The cell plasma membrane is tightly coupled with the vital processes of apoptosis and activation. In the current study, we investigated exposure of the apoptosis marker phosphatidylserine (PS) and activation marker P-selectin (CD62) on the pl
Publikováno v:
British Journal of Haematology. 161:245-254
Summary Anucleate platelets perform two fundamental processes, activation and apoptosis. We elaborated an approach for selective and concurrent stimulation of platelet apoptosis and/or activation, processes important in haemostasis and platelet clear
Autor:
Valery Leytin, Sergiy Mykhaylov, John Freedman, David J. Allen, Armen V. Gyulkhandanyan, Asuman Mutlu
Publikováno v:
Laboratory Investigation. 89:374-384
The role of the mitochondrial permeability transition pore (MPTP) in apoptosis of nucleated cells is well documented. In contrast, the role of MPTP in apoptosis of anucleated platelets is largely unknown. The aim of this study was to elucidate the co
Publikováno v:
British Journal of Haematology. 142:494-497
Publikováno v:
British journal of haematology. 169(1)
Autor:
Asuman Mutlu, Susannah Gal
Publikováno v:
Physiologia Plantarum. 105:569-576
Plant aspartic proteinases have been characterized from seeds, flowers and leaves of a number of different species. The enzymes are generally either monomeric or heterodimeric, containing two peptides processed from the same precursor protein. The pl
The aspartic proteinase is expressed inArabidopsis thalianaseeds and localized in the protein bodies
Publikováno v:
Seed Science Research. 9:75-84
We have been studying a seed aspartic proteinase, termed AtAP, fromArabidopsis thaliana.In previous work, we purified the proteinase, analysed its activity and isolated the cDNA sequence. In this paper, the expression of the mRNA for the aspartic pro
Publikováno v:
Thrombosis research. 133(1)
Background Depolarization of mitochondrial inner transmembrane potential (ΔΨm) is a key biochemical manifestation of the intrinsic apoptosis pathway in anucleate platelets. Little is known, however, about the relationship between ΔΨm depolarizati
Publikováno v:
British Journal of Haematology.
Platelet apoptosis and activation have been studied in human platelets treated with BH3-only mimetic ABT-737 and calcium ionophore A23187, agents triggering apoptosis through the intrinsic mitochondrial pathway. Platelet apoptosis was determined as a