Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Asuka Onuma"'
Publikováno v:
The Journal of Reproduction and Development, Vol 65, Iss 5, Pp 407-412 (2019)
Exportin 6, which functions specifically in the nuclear export of actin family proteins, has been reported to be absent in immature Xenopus oocytes, which have a huge nucleus containing a large amount of actin. In mammalian oocytes, however, the pres
Externí odkaz:
https://doaj.org/article/cdd65bf23d7c4da193cfe1a052dfbacb
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Activation of NF-κB transcription factors is critical for innate immune cells to induce inflammation and fight against microbial pathogens. On the other hand, the excessive and prolonged activation of NF-κB causes massive inflammatory damage to the
Externí odkaz:
https://doaj.org/article/539891c83bb74a5babb081811dc287ef
Publikováno v:
Biology of Reproduction. 98:501-509
Exportin 1 (XPO1) is a nuclear transport receptor involved in the nuclear export of majority proteins in somatic cells. In mammalian oocytes, however, only the presence of XPO1 has been reported at mRNA and protein levels, and the definitive function
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64ff6feeafa879e0f8a13dd668c63b88
https://doi.org/10.1093/biolre/iox168
https://doi.org/10.1093/biolre/iox168
Autor:
Wataru Fujii, Koji Sugiura, Kunihiko Naito, Kazuma Yasuhara, Asuka Onuma, Yoshie A. Fujioka, Yuta Matsuno
Publikováno v:
Journal of Reproduction and Development. 63:51-58
Cell-secreted vesicles, such as exosomes, have recently been recognized as mediators of cell communication. A recent study in cattle showed the involvement of exosome-like vesicles in the control of cumulus expansion, a prerequisite process for norma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::092e4f3a3a87a106bbc45269aee77f9b
https://doi.org/10.1262/jrd.2016-124
https://doi.org/10.1262/jrd.2016-124
Publikováno v:
Molecular Reproduction and Development. 83:983-992
SUMMARY Cyclin B (CCNB) accumulation is essential for regulating maturation/M-phase promoting factor activity during vertebrate oocyte maturation. Anaphase-promoting-complex/cyclosome (APC/C) degrades CCNB, allowing the cell cycle to progress; this c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::07fa1a5c5b1447aa73f89a136bbee9af
https://doi.org/10.1002/mrd.22738
https://doi.org/10.1002/mrd.22738
Publikováno v:
The Journal of Reproduction and Development
Vertebrate oocytes arrested at the first meiotic prophase must proceed to the second meiotic metaphase (MII) before fertilization. This meiotic process requires the precise control of protein degradation. Part of the protein degradation in oocytes is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35606619c4ffb5b186c5a2c556cc1103
https://pubmed.ncbi.nlm.nih.gov/29576589
https://pubmed.ncbi.nlm.nih.gov/29576589
Autor:
Chihiro Emori, Kunihiko Naito, Yuta Matsuno, Asuka Onuma, Yoshie A. Fujioka, Wataru Fujii, Koji Sugiura
Publikováno v:
Animal Science Journal. 87:1114-1121
Oocytes play critical roles in regulating the expression of transcripts encoding the glycolytic enzymes phosphofructokinase, platelet (PFKP) and lactate dehydrogenase A (LDHA) in granulosa cells in mice, but whether this is the case in pigs or other
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::18428a20d00b4c589202a5687713db79
https://doi.org/10.1111/asj.12539
https://doi.org/10.1111/asj.12539
Publikováno v:
Journal of Reproduction and Development. 61:589-593
The generation efficiencies of mutation-induced mice when using engineered zinc-finger nucleases (ZFNs) have been generally 10 to 20% of obtained pups in previous studies. The discovery of high-affinity DNA-binding modules can contribute to the gener
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b4f1669609ba15f9da382140f4d85765
https://doi.org/10.1262/jrd.2015-087
https://doi.org/10.1262/jrd.2015-087
Publikováno v:
Biochemical and Biophysical Research Communications. 445(4):791-794
The mammalian zygote-mediated CRISPR/Cas system can efficiently generate targeted genome-modified animals. However, this system is limited by the risk of off-target mutations. Here we show that offset-nicking by Cas9 nickase and paired gRNAs allows u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::653f97b18eda73aa2b31ba00050e70a6
Publikováno v:
The Journal of Reproduction and Development
Triple-knockout mice generated by the one-step CRISPR/Cas9 system were examined for the effects of multiple gene modifications on each phenotype and individual gene function. Sixty embryos were transferred, and 9 pups were obtained; all 9 pups had mu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0f206714f64974b47cd2f582d892c55
https://doi.org/10.1262/jrd.2013-139
https://doi.org/10.1262/jrd.2013-139