Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Asuka Kamio"'
Autor:
Ryuichiro Nakato, Youichiro Wada, Ryo Nakaki, Genta Nagae, Yuki Katou, Shuichi Tsutsumi, Natsu Nakajima, Hiroshi Fukuhara, Atsushi Iguchi, Takahide Kohro, Yasuharu Kanki, Yutaka Saito, Mika Kobayashi, Akashi Izumi-Taguchi, Naoki Osato, Kenji Tatsuno, Asuka Kamio, Yoko Hayashi-Takanaka, Hiromi Wada, Shinzo Ohta, Masanori Aikawa, Hiroyuki Nakajima, Masaki Nakamura, Rebecca C. McGee, Kyle W. Heppner, Tatsuo Kawakatsu, Michiru Genno, Hiroshi Yanase, Haruki Kume, Takaaki Senbonmatsu, Yukio Homma, Shigeyuki Nishimura, Toutai Mitsuyama, Hiroyuki Aburatani, Hiroshi Kimura, Katsuhiko Shirahige
Publikováno v:
Epigenetics & Chromatin, Vol 12, Iss 1, Pp 1-16 (2019)
Abstract Background Endothelial cells (ECs) make up the innermost layer throughout the entire vasculature. Their phenotypes and physiological functions are initially regulated by developmental signals and extracellular stimuli. The underlying molecul
Externí odkaz:
https://doaj.org/article/360a125b620f4aad860552d5cf426796
Autor:
Julie Brind’Amour, Hisato Kobayashi, Julien Richard Albert, Kenjiro Shirane, Akihiko Sakashita, Asuka Kamio, Aaron Bogutz, Tasuku Koike, Mohammad M. Karimi, Louis Lefebvre, Tomohiro Kono, Matthew C. Lorincz
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
De novo DNA methylation during mouse oogenesis occurs within transcribed regions. Here the authors investigate the role of species-specific long terminal repeats (LTRs)-initiated transcription units in regulating the oocyte methylome, identifying syn
Externí odkaz:
https://doaj.org/article/bee0bd7cd38c4fa6acd4a2ae886f0f09
Autor:
Kannosuke Yabe1, Asuka Kamio1, Satoyo Oya1, Tetsuji Kakutani1, Mami Hirayama1, Yuriko Tanaka1, Soichi Inagaki1 soinagak@bs.s.u-tokyo.ac.jp
Publikováno v:
Science Advances. 6/28/2024, Vol. 10 Issue 26, p1-10. 10p.
Autor:
Satoshi Ota, Genta Nagae, Yasuharu Kanki, Yotaro Kudo, Keisuke Tateishi, Shogo Yamamoto, Tsuyoshi Osawa, Ryo Nakaki, Atsushi Okabe, Yutaka Midorikawa, Asuka Kamio, Kiyokazu Shirai, Akimasa Hayashi, Takanori Fujita, Motoaki Seki, Hiroyuki Aburatani, Shuichi Tsutsumi, Masao Ichinose
Publikováno v:
Cancer Science
Ten‐eleven translocation 1 (TET1) is an essential methylcytosine dioxygenase of the DNA demethylation pathway. Despite its dysregulation being known to occur in human cancer, the role of TET1 remains poorly understood. In this study, we report that
Autor:
Akihiko Sakashita, Hisato Kobayashi, Yuko Jincho, Yukiko Kawabata, Yasuhisa Matsui, Tomoya Takashima, Tomohiro Kono, Asuka Kamio
Publikováno v:
Epigenomics. 11:543-561
Aims: Epigenetic signatures of germline cells are dynamically reprogrammed to induce appropriate differentiation, development and sex specification. We investigated sex-specific epigenetic changes in mouse fetal germ cells (FGCs) and neonatal germ ce
Autor:
Asuka Kamio, Mohammad M. Karimi, Julien Richard Albert, Kenjiro Shirane, Matthew C. Lorincz, Louis Lefebvre, Tomohiro Kono, Akihiko Sakashita, Hisato Kobayashi, Tasuku Koike, Aaron B. Bogutz, Julie Brind’Amour
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
Nature Communications
Nature Communications
De novo DNA methylation (DNAme) during mouse oogenesis occurs within transcribed regions enriched for H3K36me3. As many oocyte transcripts originate in long terminal repeats (LTRs), which are heterogeneous even between closely related mammals, we exa
Autor:
Asuka Takehara, Yukiko Tando, Asuka Kamio, Kei Otsuka, Yumi Ito-Matsuoka, Tamotsu Sekinaka, Kentaro Mochizuki, Yohei Hayashi, Yasuhisa Matsui, Tomohiro Kono, Hisato Kobayashi, Noriko Osumi
Publikováno v:
Development (Cambridge, England). 145(23)
In mouse embryos, Primordial germ cells (PGCs) are fate-determined from epiblast cells. Signaling pathways involved in PGC formation have been identified, but their epigenetic mechanisms remain poorly understood. Here, we show that SETDB1 histone met
Autor:
Hidefumi Shiota, Asuka Kamio, Akimitsu Okamoto, Takayoshi Umeda, Kenta Koyama, Genta Nagae, Gosuke Hayashi, Hiroyuki Aburatani
Publikováno v:
Journal of the American Chemical Society. 138(43)
5-Hydroxymethylcytosine (hmC) is an essential intermediate in the active DNA demethylation pathway. Here we report a new base-resolution method for measuring hmC by combining peroxotungstate-mediated oxidation and sequencing analysis. We reveal that
Autor:
George R. Wendt, Atsushi Iwama, Genta Nagae, Koutaro Yokote, Haruhiko Koseki, Yutaka Suzuki, Asuka Kamio, Motohiko Oshima, Seishi Ogawa, Tomoya Muto, Satoru Miyagi, Chiaki Nakaseko, Yasunobu Nagata, Kazuya Shimoda, Masashi Sanada, Makiko Mochizuki-Kashio, Sumio Sugano, Atsunori Saraya, Goro Sashida, Hiroyuki Aburatani
Publikováno v:
The Journal of Experimental Medicine
Deletion of Ezh2 results in transcriptional repression of developmental regulator genes, derepression of oncogenic polycomb targets, and induction of MDS/MPN-like disease in mice that is exacerbated by concurrent deletion of Tet2.
Polycomb group
Polycomb group
Autor:
Ryoichiro Kageyama, Keiko Takemoto, Yoichi Shinkai, Asuka Kamio-Miura, Miyuki Nishi, Matsui Toshiyuki, Siok-Lay Tan, Hiroyuki Aburatani, Toshiyuki Ohtsuka
Publikováno v:
Development (Cambridge, England). 139(20)
In the developing brain, neural progenitor cells switch differentiation competency by changing gene expression profiles that are governed partly by epigenetic control, such as histone modification, although the precise mechanism is unknown. Here we f