Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Asuka Eguchi"'
Publikováno v:
npj Regenerative Medicine, Vol 7, Iss 1, Pp 1-11 (2022)
Abstract Duchenne muscular dystrophy (DMD) is a progressive genetic myopathy that leads to heart failure from dilated cardiomyopathy by early adulthood. Recent evidence suggests that tamoxifen, a selective estrogen receptor modulator widely used to t
Externí odkaz:
https://doaj.org/article/bcc03fc6d7194bfeb4c491a1753444ab
Publikováno v:
PLoS ONE, Vol 15, Iss 12, p e0243905 (2020)
Pyrrole-imidazole (Py-Im) polyamides are synthetic molecules that can be rationally designed to target specific DNA sequences to both disrupt and recruit transcriptional machinery. While in vitro binding has been extensively studied, in vivo effects
Externí odkaz:
https://doaj.org/article/e69207fc8c78448ca363229f849bd1bd
Autor:
Asuka Eguchi, Adriana Fernanda G. S. Gonzalez, Sofía I. Torres-Bigio, Kassie Koleckar, Foster Birnbaum, Joe Z. Zhang, Vicky Y. Wang, Joseph C. Wu, Steven E. Artandi, Helen M. Blau
Publikováno v:
Proceedings of the National Academy of Sciences. 120
Duchenne muscular dystrophy (DMD) is a severe muscle wasting disease caused by the lack of dystrophin. Heart failure, driven by cardiomyocyte death, fibrosis, and the development of dilated cardiomyopathy, is the leading cause of death in DMD patient
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c100dc3f0bf020c2f043b9d27dd42ebd
https://doi.org/10.1073/pnas.2209967120
https://doi.org/10.1073/pnas.2209967120
Autor:
Asuka Eguchi, Adriana Fernanda Gonzalez, Sofia Torres-Bigio, Sriram Bhimaraju, Foster Birnbaum, Helen M Blau
Publikováno v:
Circulation Research. 131
Duchenne muscular dystrophy (DMD) is a severe muscle wasting disease caused by the lack of dystrophin. Dilated cardiomyopathy is the leading cause of death in DMD patients. Preclinical data show that smaller versions of dystrophin, called microdystro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::950e4ce13a4cee4e5cec3bf1748f8b42
https://doi.org/10.1161/res.131.suppl_1.p2120
https://doi.org/10.1161/res.131.suppl_1.p2120
Autor:
Asuka Eguchi, Sofia I Torres-Bigio, Adriana Fernanda G Gonzalez, Kassie Koleckar, Foster Birnbaum, Helen M Blau
Publikováno v:
Circulation Research. 131
Duchenne muscular dystrophy (DMD) is a severe muscle wasting disease caused by the lack of dystrophin. Heart failure, driven by cardiomyocyte death, fibrosis, and the development of dilated cardiomyopathy, is the leading cause of death in DMD patient
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::79fc2f3c2370ad9b9ae847eb5403f0bd
https://doi.org/10.1161/res.131.suppl_1.p2117
https://doi.org/10.1161/res.131.suppl_1.p2117
Autor:
Edward L. LaGory, Colin Holbrook, Sang-Ging Ong, Chris Denning, Andrew H. Chang, John W. Day, Martin K. Childers, Alexandre J.S. Ribeiro, Honghui Wang, Alex C.Y. Chang, Gaspard Pardon, Joseph C. Wu, Kassie Koleckar, Sara Ancel, Helen M. Blau, David L. Mack, John Ramunas, Amato J. Giaccia, Asuka Eguchi, Haodi Wu, Beth L. Pruitt
Publikováno v:
Stem Cell Reports
Stem cell reports, vol 16, iss 9
Stem cell reports, vol 16, iss 9
Summary Duchenne muscular dystrophy (DMD) is a rare X-linked recessive disease that is associated with severe progressive muscle degeneration culminating in death due to cardiorespiratory failure. We previously observed an unexpected proliferation-in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::daf4f33a749dacf9fabe0ac58ad2bd32
http://europepmc.org/articles/PMC8452491
http://europepmc.org/articles/PMC8452491
Autor:
Asuka Eguchi, Sofía I. Torres-Bigio, Kassie Koleckar, Adriana Fernanda G. S. Gonzalez, Foster Birnbaum, Helen M. Blau
Duchenne muscular dystrophy (DMD) is a severe muscle wasting disease caused by the lack of dystrophin. Heart failure, driven by cardiomyocyte death, fibrosis, and the development of dilated cardiomyopathy, is the leading cause of death in DMD patient
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::205e1d1ed7cc0f10ab7168408d138023
https://doi.org/10.1101/2022.01.10.475653
https://doi.org/10.1101/2022.01.10.475653
Publikováno v:
NPJ Regenerative medicine. 7(1)
Duchenne muscular dystrophy (DMD) is a progressive genetic myopathy that leads to heart failure from dilated cardiomyopathy by early adulthood. Recent evidence suggests that tamoxifen, a selective estrogen receptor modulator widely used to treat brea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6ba17f0cc568d2ff9a89c3e5e331dd8
https://pubmed.ncbi.nlm.nih.gov/35304486
https://pubmed.ncbi.nlm.nih.gov/35304486
Publikováno v:
Circulation Research. 127
Duchenne Muscular Dystrophy (DMD) is a lethal X-chromosome linked disease that affects ~1:3500 boys and culminates in heart failure in early adulthood. DMD results from >200 possible dystrophin mutations. The lack of dystrophin disrupts the anchoring
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f7b197f0a544fd52fed77fa333fcbd59
https://doi.org/10.1161/res.127.suppl_1.522
https://doi.org/10.1161/res.127.suppl_1.522
Publikováno v:
PLoS ONE, Vol 15, Iss 12, p e0243905 (2020)
PLoS ONE
PLoS ONE
Regulating desired loci in the genome with sequence-specific DNA-binding molecules is a major goal for the development of precision medicine. Pyrrole–imidazole (Py–Im) polyamides are synthetic molecules that can be rationally designed to target s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abc7eab711137ed5d50961142a259fbc
https://doaj.org/article/e69207fc8c78448ca363229f849bd1bd
https://doaj.org/article/e69207fc8c78448ca363229f849bd1bd