Výsledky vyhledávání - "Astudillo Aurora"

Akademický článek

Specific genes involved in synthesis and editing of heparan sulfate proteoglycans show altered expression patterns in breast cancer

Autor: Fernández-Vega Iván, García Olivia, Crespo Ainara, Castañón Sonia, Menéndez Primitiva, Astudillo Aurora, Quirós Luis M

Publikováno v: BMC Cancer, Vol 13, Iss 1, p 24 (2013)

Abstract Background The expression of a specific set of genes controls the different structures of heparan sulfate proteoglycans (HSPGs), which are involved in the growth, invasion and metastatic properties of cancerous cells. The purpose of this stu

Externí odkaz: https://doaj.org/article/e853194f685c4297af4e9e92b8cf122c

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Akademický článek

Germ-line mutations in epidermal growth factor receptor (EGFR) are rare but may contribute to oncogenesis: A novel germ-line mutation in EGFR detected in a patient with lung adenocarcinoma

Autor: Menéndez Primitiva, Iglesias Fernando, González-Arriaga Patricia, Osorio Fernando G, Pitiot Ana S, Astudillo Aurora, Santamaría Iñigo, Blay Pilar, Centeno Irene, Tardón Adonina, Freije Jose M, Balbín Milagros

Publikováno v: BMC Cancer, Vol 11, Iss 1, p 172 (2011)

Abstract Background A subset of lung cancer patients harbour EGFR somatic mutations in their tumours and are candidates for treatment with EGFR tyrosine kinase inhibitors. In a few cases EGFR mutations have also been found in the germ line, suggestin

Externí odkaz: https://doaj.org/article/f3cf86d518c249ada2b8fcfa8b346023

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Akademický článek

Prognostic significance of lymphangiogenesis in pharyngolaryngeal carcinoma patients

Autor: Garcia-Carracedo Darío, Rodrigo Juan, Astudillo Aurora, Nieto Carlos, Gonzalez Maria

Publikováno v: BMC Cancer, Vol 10, Iss 1, p 416 (2010)

Abstract Background Lymphatic vessel spread is considered a major route for head and neck squamous cell carcinoma metastasis. Formation of new lymphatic vessels could facilitate the process, raising the malignant potential of these tumours. Recent id

Externí odkaz: https://doaj.org/article/8d4d17338ea54ddab971018418c4138d

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Akademický článek

Epigenetic repression of ROR2 has a Wnt-mediated, pro-tumourigenic role in colon cancer

Autor: López-Otín Carlos, Muñoz Alberto, Astudillo Aurora, Sánchez Laura, González-Sancho José, Aguilera Oscar, Obaya Álvaro J, Moncada-Pazos Ángela, Fernández Agustin F, Huidobro Covadonga, Calvanese Vincenzo, Lara Ester, Esteller Manel, Fraga Mario F

Publikováno v: Molecular Cancer, Vol 9, Iss 1, p 170 (2010)

Abstract Background Wnt factors control cell differentiation through semi-independent molecular cascades known as the β-catenin-dependent (canonical) and -independent (non-canonical) Wnt signalling pathways. Genetic and epigenetic alteration of comp

Externí odkaz: https://doaj.org/article/67e35861669b411b931b591ed00dee47

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Akademický článek

The role of pneumolysin in mediating lung damage in a lethal pneumococcal pneumonia murine model

Autor: Pirofski Liise-Anne, Fabrizio Kevin, Villaverde Roberto, Vázquez Fernando, Astudillo Aurora, Flórez Noelia, García-Suárez María del Mar, Méndez Francisco J

Publikováno v: Respiratory Research, Vol 8, Iss 1, p 3 (2007)

Abstract Background Intranasal inoculation of Streptococcus pneumoniae D39 serotype 2 causes fatal pneumonia in mice. The cytotoxic and inflammatory properties of pneumolysin (PLY) have been implicated in the pathogenesis of pneumococcal pneumonia. M

Externí odkaz: https://doaj.org/article/134a520d44c94e0c9c46825ab0534cc9

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