Výsledky vyhledávání - "Astsaturov, I. A."

CRISPR/Cas9 Technique for Identification of Genes Regulating Oxaliplatin Resistance of Pancreatic Cancer Cell Line

Autor: Skripova V., Serebriiskii I., Abramova Z., Astsaturov I., Kiyamova R.

Publikováno v: SCOPUS21911630-2017-7-1-SID85017618830

© 2016, Springer Science+Business Media New York.Genome editing approach based on prokaryotic CRISPR (clustered regularly interspaced short palindromic repeats) system is a simple and useful way to investigate gene functions on a genome-wide scale.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::2aaa087f774f2c6f1390a96e2a760d52
https://openrepository.ru/article?id=223155

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Akademický článek

61P CRISPR/Cas9 and bioinformatics approaches revealed new regulators of pancreatic cancer cells platinum sensitivity

Autor: Skripova, V., Vlasenkova, R., Astsaturov, I., Kiyamova, R.

Publikováno v: In Annals of Oncology October 2020 31 Supplement 5:S1235-S1236

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Induction Therapy for Locally Advanced, Resectable Esophagogastric Cancer: A Phase I Trial of Vandetanib (ZD6474), Paclitaxel, Carboplatin, 5-Fluorouracil, and Radiotherapy Followed by Resection

Autor: Boland P., Meyer J., Berger A., Cohen S., Neuman T., Cooper H., Olszanski A., Davey M., Cheng J., Lebenthal A., Burtness B., Scott W., Astsaturov I.

Publikováno v: SCOPUS02773732-2016-SID84961233826

Copyright © 2016 Wolters Kluwer Health, Inc. All rights reserved.OBJECTIVES:: Preoperative chemotherapy and radiation for localized esophageal cancer produces cure rates near 30% when combined with surgical resection. Vandetanib, a small molecule re

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::236c18dc69855528275ab96b6a6cb2a4
https://openrepository.ru/article?id=51899

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EGFR and RB1 as dual biomarkers in HPV-negative head and neck cancer

Autor: Beck T., Georgopoulos R., Shagisultanova E., Sarcu D., Handorf E., Dubyk C., Lango M., Ridge J., Astsaturov I., Serebriiskii I., Burtness B., Mehra R., Golemis E.

Publikováno v: SCOPUS15357163-2016-15-10-SID84990985902

© 2016 American Association for Cancer Research.Clinical decision making for human papillomavirus (HPV)-negative head and neck squamous cell carcinoma (HNSCC) is predominantly guided by disease stage and anatomic location, with few validated biomark

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::0fa2bb214bb36a1670720cf9591def51
https://openrepository.ru/article?id=222429

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Screening of conditionally reprogrammed patient-derived carcinoma cells identifies ERCC3-MYC interactions as a target in pancreatic cancer

Publikováno v: SCOPUS10780432-2016-22-24-SID85006985653

©2016 AACR.Purpose: Even when diagnosed prior to metastasis, pancreatic ductal adenocarcinoma (PDAC) is a devastating malignancy with almost 90% lethality, emphasizing the need for new therapies optimally targeting the tumors of individual patients.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::7a24c70a0a33fda419bb95f0464b9e62
https://openrepository.ru/article?id=222153

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Endogenous Sterol Metabolites Regulate Growth of EGFR/KRAS-Dependent Tumors via LXR

Autor: Gabitova L., Restifo D., Gorin A., Manocha K., Handorf E., Yang D., Cai K., Klein-Szanto A., Cunningham D., Kratz L., Herman G., Golemis E., Astsaturov I.

Publikováno v: SCOPUS-2015-12-11-SID84942821941

© 2015 The Authors. Meiosis-activating sterols (MAS) are substrates of SC4MOL and NSDHL in the cholesterol pathway and are important for normal organismal development. Oncogenic transformation by epidermal growth factor receptor (EGFR) or RAS increa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::38ef20896ed1c1ff56d585937a722d45
https://openrepository.ru/article?id=676371

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Akademický článek

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Molecular pathways: Sterols and receptor signaling in cancer

Autor: Gabitova L., Gorin A., Astsaturov I.

Publikováno v: SCOPUS10780432-2014-20-1-SID84892170909

Accelerated cholesterol and lipid metabolism are the hallmarks of cancer and contribute to malignant transformation due to the obligatory requirement for cholesterol for the function of eukaryotic membranes. To build new membranes and maintain active

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::52b57cca0543e1ff0366b5807a824286
https://openrepository.ru/article?id=209006

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