Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Astrid Zayas‐Santiago"'
Autor:
Astrid Zayas-Santiago, Christian J. Malpica-Nieves, David S. Ríos, Amanda Díaz-García, Paola N. Vázquez, José M. Santiago, David E. Rivera-Aponte, Rüdiger W. Veh, Miguel Méndez-González, Misty Eaton, Serguei N. Skatchkov
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 12, p 6458 (2024)
Polyamine (PA) spermidine (SPD) plays a crucial role in aging. Since SPD accumulates in glial cells, particularly in Müller retinal cells (MCs), the expression of the SPD-synthesizing enzyme spermidine synthase (SpdS) in Müller glia and age-depende
Externí odkaz:
https://doaj.org/article/ef17f7e2291f423690a72078923a4920
Autor:
Astrid Zayas‐Santiago, Michelle M. Martínez‐Montemayor, Jadier Colón‐Vázquez, Gabriela Ortiz‐Soto, Jose G. Cirino‐Simonet, Mikhail Inyushin
Publikováno v:
FEBS Open Bio, Vol 12, Iss 1, Pp 95-105 (2022)
Accumulation of amyloid in breast cancer is a well‐known phenomenon, but only immunoglobulin light‐chain amyloidosis (AL) or transthyretin (TTR) amyloid had been detected in human breast tumor samples previously. We recently reported that another
Externí odkaz:
https://doaj.org/article/f1f4d27d61af44028cff34f3e0161032
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
As do many other immunity-related blood cells, platelets release antimicrobial peptides that kill bacteria, fungi, and even certain viruses. Here we review the literature suggesting that there is a similarity between the antimicrobials released by ot
Externí odkaz:
https://doaj.org/article/3063101056b34d3c9fafa83fa77a2e7d
Autor:
Antonio Henrique Martins, Astrid Zayas-Santiago, Yancy Ferrer-Acosta, Solianne M. Martinez-Jimenez, Lidia Zueva, Amanda Diaz-Garcia, Mikhail Inyushin
Publikováno v:
Biomolecules, Vol 9, Iss 8, p 350 (2019)
It is well known that amyloid beta (Aβ) peptides are generated in blood vessels, released into the brain during thrombosis, and temporarily accumulate in this organ after injury. Here we demonstrate that 24 h after transient middle cerebral artery o
Externí odkaz:
https://doaj.org/article/99abe6625d9249fc8fd249497b58c841
Publikováno v:
Molecules, Vol 24, Iss 13, p 2388 (2019)
In vivo tissue transparency in the visible light spectrum is beneficial for many research applications that use optical methods, whether it involves in vivo optical imaging of cells or their activity, or optical intervention to affect cells or their
Externí odkaz:
https://doaj.org/article/b09caa7bcb5b4c11b71e1df22a1a54d2
Autor:
Ariana Acevedo-Díaz, Gabriela Ortiz-Soto, Ivette J. Suárez-Arroyo, Astrid Zayas-Santiago, Michelle M. Martínez Montemayor
Publikováno v:
Nutrients, Vol 11, Iss 5, p 1116 (2019)
Breast cancer (BC) is the second leading cause of cancer death among women worldwide. The main cause of BC morbidity and mortality is the invasiveness capacity of cancer cells that may lead to metastasis. Here, we aimed to investigate the therapeutic
Externí odkaz:
https://doaj.org/article/2d733e6d0d5e470a9d1c93eefc0e3ab2
Autor:
Lilia Y. Kucheryavykh, Jescelica Ortiz-Rivera, Yuriy V. Kucheryavykh, Astrid Zayas-Santiago, Amanda Diaz-Garcia, Mikhail Y. Inyushin
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 10, p 2482 (2019)
Immunostaining with specific antibodies has shown that innate amyloid beta (Aβ) is accumulated naturally in glioma tumors and nearby blood vessels in a mouse model of glioma. In immunofluorescence images, Aβ peptide coincides with glioma cells, and
Externí odkaz:
https://doaj.org/article/4f2818a0a01e4006b35f466be85e181b
Autor:
Aixa F Rivera-Pagán, David E Rivera-Aponte, Katya V Melnik-Martínez, Astrid Zayas-Santiago, Lilia Y Kucheryavykh, Antonio H Martins, Luis A Cubano, Serguei N Skatchkov, Misty J Eaton
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0125195 (2015)
Excitotoxicity due to glutamate receptor over-activation is one of the key mediators of neuronal death after an ischemic insult. Therefore, a major function of astrocytes is to maintain low extracellular levels of glutamate. The ability of astrocytic
Externí odkaz:
https://doaj.org/article/31916e1c1dd743fa8bdcf473a6f8b08a
Autor:
Astrid Zayas-Santiago, Silke Agte, Yomarie Rivera, Jan Benedikt, Elke Ulbricht, Anett Karl, José Dávila, Alexey Savvinov, Yuriy Kucheryavykh, Mikhail Inyushin, Luis A Cubano, Thomas Pannicke, Rüdiger W Veh, Mike Francke, Alexei Verkhratsky, Misty J Eaton, Andreas Reichenbach, Serguei N Skatchkov
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e97155 (2014)
Müller cells, the principal glial cells of the vertebrate retina, are fundamental for the maintenance and function of neuronal cells. In most vertebrates, including humans, Müller cells abundantly express Kir4.1 inwardly rectifying potassium channe
Externí odkaz:
https://doaj.org/article/31cfdd52a36b40e396836f8d86511006
Autor:
Jose G. Cirino-Simonet, Mikhail Inyushin, Michelle M. Martínez-Montemayor, Gabriela Ortiz-Soto, Jadier Colón-Vázquez, Astrid Zayas-Santiago
Publikováno v:
FEBS Open Bio, Vol 12, Iss 1, Pp 95-105 (2022)
FEBS Open Bio
FEBS Open Bio
Accumulation of amyloid in breast cancer is a well‐known phenomenon, but only immunoglobulin light‐chain amyloidosis (AL) or transthyretin (TTR) amyloid had been detected in human breast tumor samples previously. We recently reported that another