Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Astrid S. Jørgensen"'
Autor:
Astrid S. Jørgensen, Viktorija Daugvilaite, Katia De Filippo, Christian Berg, Masa Mavri, Tau Benned-Jensen, Goda Juzenaite, Gertrud Hjortø, Sara Rankin, Jon Våbenø, Mette M. Rosenkilde
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-12 (2021)
Jørgensen et al. investigate the effects of the CXCR4 targeting agents, AMD3100 (Plerixafor) and AMD11070, and show that AMD3100, unlike AMD11070, is biased with intrinsic β-arrestin recruitment agonism and full G protein antagonism. They finally p
Externí odkaz:
https://doaj.org/article/d920693ad8d842c78b29bd1b15141947
Autor:
Astrid S. Jørgensen, Olav Larsen, Edith Uetz-von Allmen, Michael Lückmann, Daniel F. Legler, Thomas M. Frimurer, Christopher T. Veldkamp, Gertrud M. Hjortø, Mette M. Rosenkilde
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Chemokine receptors play important roles in the immune system and are linked to several human diseases. Targeting chemokine receptors have so far shown very little success owing to, to some extent, the promiscuity of the immune system and the high de
Externí odkaz:
https://doaj.org/article/adc9d50f5c624485a70b0f829f9929bd
Autor:
Viktoria M. S. Kjær, Viktorija Daugvilaite, Tomasz M. Stepniewski, Christian M. Madsen, Astrid S. Jørgensen, Kaustubh R. Bhuskute, Asuka Inoue, Trond Ulven, Tau Benned-Jensen, Siv A. Hjorth, Gertrud M. Hjortø, Ee Von Moo, Jana Selent, Mette M. Rosenkilde
Publikováno v:
Science Signaling. 16
The chemotactic G protein–coupled receptor GPR183 and its most potent endogenous oxysterol ligand 7α,25-dihydroxycholesterol (7α,25-OHC) are important for immune cell positioning in secondary lymphoid tissues. This receptor-ligand pair is associa
Autor:
Sune K Jensen, Simone I Pærregaard, Emma P Brandum, Astrid S Jørgensen, Gertrud M Hjortø, Benjamin A H Jensen
Publikováno v:
Jensen, S K, Pærregaard, S I, Brandum, E P, Jørgensen, A S, Hjortø, G M & Jensen, B A H 2022, ' Rewiring host–microbe interactions and barrier function during gastrointestinal inflammation ', Gastroenterology Report, vol. 10, goac008, pp. 1-15 . https://doi.org/10.1093/gastro/goac008
Organismal survival depends on a well-balanced immune system and maintenance of host–microbe mutualism. The fine-tuned relationship between the gut microbiota and host immunity is constantly challenged by opportunistic bacteria testing the integrit