Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Astrid Roth-Härer"'
Publikováno v:
Brain Research. 1487:39-53
Glial cells play a crucial role in the pathomechanism of perinatal hypoxic-ischemic brain injury (HI) and are involved in the maintenance of a chronic state of inflammation that causes delayed neuronal damage. Activation of astrocytes is one factor p
Autor:
Joseph G. Vos, Aldert H. Piersma, Leo T.M. van der Ven, Alfons Hack, Hellmuth Lilienthal, Astrid Roth-Härer
Publikováno v:
Human and Ecological Risk Assessment: An International Journal. 15:76-86
The widespread use of brominated flame retardants (BFRs) has led to increasing concentrations in environmental samples. Previous reports suggested endocrine activity of these compounds. Because thyroid hormones and sex steroids are known to regulate
Autor:
Hellmuth Lilienthal, Simone Wichert Grande, Alfons Hack, Astrid Roth-Härer, Chris E. Talsness
Publikováno v:
Environmental Health Perspectives
Increasing concentrations of polybrominated flame retardants, including polybrominated diphenyl ethers (PBDEs), in breast milk cause concern about possible developmental effects in nursed babies. Because previous studies in rats have indicated effect
Autor:
Gerhard Winneke, Jürgen Hany, Astrid Roth-Härer, Walter Lichtensteiger, Alexander Sarasin, Lothar Dunemann, Hellmuth Lilienthal, Annemarie Fastabend
Publikováno v:
Toxicology and Applied Pharmacology. 158:231-243
Polychlorinated biphenyls (PCBs) are lipophilic industrial chemicals which are regularly detected in human breast milk, serum, and tissues. They possess hormone-modulating properties, and, when transferred transplacentally to the developing fetus, PC
Autor:
Birger Heinzow, Astrid Roth-Härer, Hellmuth Lilienthal, Gerhard Winneke, Jürgen Hany, Guido Ostendorp
Publikováno v:
Neurotoxicology and Teratology. 21:147-156
The present study has compared the neurobehavioral effects of two structurally different PCB congeners or their combination in rats. Time-mated Long–Evans rats received daily injections of the coplanar PCB 77 (3,4 3′,4′-TCB: 0.5 or 1.5 mg/kg),
Publikováno v:
Environmental toxicology and pharmacology. 19(3)
During development, gonadal steroids exert effects on the nervous system which are long-lasting or organizational, in contrast to the transient activational actions in adulthood. Therefore, disturbance of neuroendocrine functions by developmental exp
Publikováno v:
Geburtshilfe und Frauenheilkunde. 66
Autor:
Hatice Kaya, Annemarie Fastabend, Jürgen Hany, Astrid Roth-Härer, Hellmuth Lilienthal, Gerhard Winneke
Publikováno v:
Toxicology and applied pharmacology. 178(2)
In a previous experiment, maternal exposure to a polychlorinated biphenyl (PCB) mixture reconstituted according to the congener pattern found in human breast milk resulted in decreased aromatase activity in the brain of newborn male rats, together wi
Autor:
Thomas R. Ward, Hilke Winterhoff, Hellmuth Lilienthal, Ulrich O. Kronthaler, Astrid Roth-Härer, Michael Bubser, Werner J. Schmidt, William R. Mundy, Gerhard Winneke
Publikováno v:
Environmental toxicology and pharmacology. 9(3)
Polychlorinated biphenyls (PCBs) are environmental contaminants, which accumulate in the food chain and are transferred to the offspring during prenatal development through the placenta and postnatally via breast milk. It is reported that PCBs exert
Autor:
Hatice Kaya, Hellmuth Lilienthal, Astrid Roth-Härer, Gerhard Winneke, Jürgen Hany, Annemarie Fastabend, Lothar Dunemann
Publikováno v:
Toxicological sciences : an official journal of the Society of Toxicology. 57(2)
Previous studies revealed effects of polychlorinated biphenyls (PCBs) and other polyhalogenated hydrocarbons on steroid hormone levels and hormone-dependent functions including behavior. In the present study serum concentrations of the vitamin D 3 me