Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Astrid Roth"'
Publikováno v:
Toxins, Vol 13, Iss 5, p 307 (2021)
AB5 protein toxins are produced by certain bacterial pathogens and are composed of an enzymatically active A-subunit and a B-subunit pentamer, the latter being responsible for cell receptor recognition, cellular uptake, and transport of the A-subunit
Externí odkaz:
https://doaj.org/article/3f6230cff0db447aa6bb5effd9f8c26e
Publikováno v:
Brain Research. 1487:39-53
Glial cells play a crucial role in the pathomechanism of perinatal hypoxic-ischemic brain injury (HI) and are involved in the maintenance of a chronic state of inflammation that causes delayed neuronal damage. Activation of astrocytes is one factor p
Autor:
Joseph G. Vos, Aldert H. Piersma, Leo T.M. van der Ven, Alfons Hack, Hellmuth Lilienthal, Astrid Roth-Härer
Publikováno v:
Human and Ecological Risk Assessment: An International Journal. 15:76-86
The widespread use of brominated flame retardants (BFRs) has led to increasing concentrations in environmental samples. Previous reports suggested endocrine activity of these compounds. Because thyroid hormones and sex steroids are known to regulate
Autor:
Hellmuth Lilienthal, Simone Wichert Grande, Alfons Hack, Astrid Roth-Härer, Chris E. Talsness
Publikováno v:
Environmental Health Perspectives
Increasing concentrations of polybrominated flame retardants, including polybrominated diphenyl ethers (PBDEs), in breast milk cause concern about possible developmental effects in nursed babies. Because previous studies in rats have indicated effect
Autor:
Ivo Volf, Werner Schmid, Thomas Moeslinger, Manfred Zehetgruber, Astrid Roth, Julian Cooper, Elisabeth Koller
Publikováno v:
Thrombosis Research. 97:441-449
Oxidized low density lipoproteins are closely associated with atherosclerosis and also might be directly involved in thrombosis because they have been shown to mediate a stimulating effect on human platelets. In this work, we used biologically modifi
Autor:
Gerhard Winneke, Jürgen Hany, Astrid Roth-Härer, Walter Lichtensteiger, Alexander Sarasin, Lothar Dunemann, Hellmuth Lilienthal, Annemarie Fastabend
Publikováno v:
Toxicology and Applied Pharmacology. 158:231-243
Polychlorinated biphenyls (PCBs) are lipophilic industrial chemicals which are regularly detected in human breast milk, serum, and tissues. They possess hormone-modulating properties, and, when transferred transplacentally to the developing fetus, PC
Autor:
Birger Heinzow, Astrid Roth-Härer, Hellmuth Lilienthal, Gerhard Winneke, Jürgen Hany, Guido Ostendorp
Publikováno v:
Neurotoxicology and Teratology. 21:147-156
The present study has compared the neurobehavioral effects of two structurally different PCB congeners or their combination in rats. Time-mated Long–Evans rats received daily injections of the coplanar PCB 77 (3,4 3′,4′-TCB: 0.5 or 1.5 mg/kg),
Publikováno v:
Environmental toxicology and pharmacology. 19(3)
During development, gonadal steroids exert effects on the nervous system which are long-lasting or organizational, in contrast to the transient activational actions in adulthood. Therefore, disturbance of neuroendocrine functions by developmental exp
Autor:
Arne Jensen, Rolf Dermietzel, Astrid Roth-Haerer, Hubert R. Dinse, Johannes Middelanis, Markus Gantert, B. Wasielewski, Sandra Neuhoff, Carola Meier
Publikováno v:
Pediatric research. 59(2)
Brain damage around birth may cause lifelong neurodevelopmental deficits. We examined the therapeutic potential of human umbilical cord blood-derived mononuclear cells containing multipotent stem cells to facilitate motor recovery after cerebral hypo
Publikováno v:
Geburtshilfe und Frauenheilkunde. 66