Zobrazeno 1 - 1
of 1
pro vyhledávání: '"Astrid Polier"'
Autor:
Ralf Dittrich, Michael G. Schrauder, Matthias W. Beckmann, Ben Fabry, Sonja Oeser, Juergen Dittmer, Astrid Polier, Michael P. Lux, Inge Hoffmann, David L. Wachter, Peter A. Fasching, Pamela L. Strissel, Christian R. Loehberg, Ina Brandt, Nicole Groh, Angela Dittmer, Thorsten Koch, Florentine Koppitz, Reiner Strick, Willi A. Kalender, Andreas Mueller, Laura Lotz
Publikováno v:
Biochemical pharmacology. 83(4)
PI3K/Akt/mTOR and p53 signaling pathways are frequently deregulated in tumors. The anticancer drug RAD001 (everolimus) is a known mTOR-inhibitor, but mTOR-inhibition leads to phosphorylation of Akt inducing resistance against RAD001 treatment. There
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4c63e9ba0cc1877e39c77e0e9b00fbf
https://pubmed.ncbi.nlm.nih.gov/22142888
https://pubmed.ncbi.nlm.nih.gov/22142888
