Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Astrid Plenker"'
Publikováno v:
Clinical Drug Investigation. 22:43-52
Objective: To assess the efficacy and safety of desloratadine in the treatment of seasonal allergic rhinitis (SAR) in the clinical setting. Design and Setting: The postmarketing surveillance study was performed in Germany in 47 953 outpatients requir
Publikováno v:
International Clinical Psychopharmacology. 12:S17-S24
Electro-oculogram (including saccadic eye movements), auditory-evoked potentials and visual analogue scales for a subjective impression of effects were used to evaluate some pharmacodynamic properties of RS-8359. In the electro-oculogram, administrat
Publikováno v:
International Clinical Psychopharmacology. 12:S25-S30
The potential liability of RS-8359 for the 'cheese' effect that is characteristic of the classical monoamine oxidase inhibitors has been compared with placebo and moclobemide in the tyramine test. Both RS-8359 and moclobemide reduce the dose of tyram
Publikováno v:
International Clinical Psychopharmacology. 12:S11-S16
RS-8359 is very rapidly absorbed, metabolized and distributed following oral dosing, with significant concentrations of both parent drug and its principal metabolite appearing in plasma within 15 min. Plasma levels were linearly related to doses of u
Publikováno v:
International clinical psychopharmacology. 12
RS-8359 is a new reversible inhibitor of monoamine oxidase A (RIMA). With a selectivity ratio of about 2200 for the A:B enzyme types, it is one of the most specific of this class of compounds. As a result, it shows relatively little effect upon blood
Publikováno v:
International Clinical Psychopharmacology. 12:S31
The safety, tolerability and a preliminary assessment of the efficacy of the new reversible inhibitor of monoamine oxidase A, RS-8359, were evaluated in two studies in hospitalized, depressed patients. Daily doses of 100 and 200 mg divided into two e