Genetic Analysis of mcr-1-Carrying Plasmids From Gram-Negative Bacteria in a Dutch Tertiary Care Hospital: Evidence for Intrapatient and Interspecies Transmission Events

Autor: Nikolaos Strepis, Anne F. Voor in ’t holt, Margreet C. Vos, Willemien H. A. Zandijk, Astrid P. Heikema, John P. Hays, Juliëtte A. Severin, Corné H. W. Klaassen

Publikováno v: Frontiers in Microbiology, Vol 12 (2021)

The role of plasmids in the complex pandemic of antimicrobial resistance is increasingly being recognized. In this respect, multiple mobile colistin resistance (mcr) gene-carrying plasmids have been described. However, the characteristics and epidemi

Externí odkaz: https://doaj.org/article/3172cafd8d0e439c9c5a6807983e8cc6

Biomolecule sulphation and novel methylations related to Guillain-Barré syndrome-associated

Autor: Astrid P, Heikema, Nikolaos, Strepis, Deborah, Horst-Kreft, Steven, Huynh, Aldert, Zomer, David J, Kelly, Kerry K, Cooper, Craig T, Parker

Publikováno v: Microbial Genomics

Campylobacter jejuni strains that produce sialylated lipooligosaccharides (LOS) can cause the immune-mediated disease Guillain-Barré syndrome (GBS). The risk of GBS after infection with C. jejuni Penner serotype HS:19 is estimated to be at least six

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::37520924f20b17f1956e3cda79c2a444
https://pubmed.ncbi.nlm.nih.gov/34723785

The Role of the Respiratory Microbiome and Viral Presence in Lower Respiratory Tract Infection Severity in the First Five Years of Life

Autor: Astrid P. Heikema, Janine Punt, John P. Hays, Gerdien A. Tramper-Stranders, Frank J Smit, Anne-Marie van Wermerskerken, Willem de Koning, Ivo Hoefnagels, Annemarie M. C. van Rossum, Rianne Oostenbrink, Charlie C. Obihara, Andrew P. Stubbs, Josephine van de Maat, Deborah Horst-Kreft, Jeroen J. A. van Kampen, GJ Driessen, Jeroen G. Noordzij

Publikováno v: Microorganisms, Vol 9, Iss 1446, p 1446 (2021)
Microorganisms, 9(7). Multidisciplinary Digital Publishing Institute (MDPI)
Microorganisms, 9(7):1446. Multidisciplinary Digital Publishing Institute (MDPI)
Microorganisms
Volume 9
Issue 7

Lower respiratory tract infections (LRTIs) in children are common and, although often mild, a major cause of mortality and hospitalization. Recently, the respiratory microbiome has been associated with both susceptibility and severity of LRTI. In thi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f59311a48c2a3bcbfd5f79015063fd70
https://www.mdpi.com/2076-2607/9/7/1446

Lessons learnt from the introduction of nanopore sequencing

Autor: John P. Hays, Astrid P. Heikema, W. de Koning, Andrew P. Stubbs, Yunlei Li

Publikováno v: Clinical Microbiology and Infection, 26(10), 1286-1288. Elsevier Ltd.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bca86d43aee3e8c741eae11e70e32512
https://pubmed.ncbi.nlm.nih.gov/32505585

Comparison of Illumina versus Nanopore 16S rRNA Gene Sequencing of the Human Nasal Microbiota

Autor: Maria A. J. de Ridder, Willem de Koning, Chantal B. van Houten, Deborah Horst-Kreft, Rick Jansen, Andrew P. Stubbs, John P. Hays, Astrid P. Heikema, Robert Kraaij, Stefan A. Boers, Saskia Hiltemann, Louis Bont

Publikováno v: Genes
Genes, Vol 11, Iss 1105, p 1105 (2020)
Genes, 11(9):E1105. Multidisciplinary Digital Publishing Institute (MDPI)
Volume 11
Issue 9

Illumina and nanopore sequencing technologies are powerful tools that can be used to determine the bacterial composition of complex microbial communities. In this study, we compared nasal microbiota results at genus level using both Illumina and nano

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92a294d372c47d851d9723acb6f0ac1a
https://doi.org/10.3390/genes11091105