Profiling of peripheral blood B-cell transcriptome in children who developed coeliac disease in a prospective studyResearch in context

Autor: Astrid Oras, Henna Kallionpää, Tomi Suomi, Satu Koskinen, Asta Laiho, Laura L. Elo, Mikael Knip, Riitta Lahesmaa, Alar Aints, Raivo Uibo

Publikováno v: Heliyon, Vol 9, Iss 2, Pp e13147- (2023)

Background: In coeliac disease (CoD), the role of B-cells has mainly been considered to be production of antibodies. The functional role of B-cells has not been analysed extensively in CoD. Methods: We conducted a study to characterize gene expressio

Externí odkaz: https://doaj.org/article/94febd692ccf486ebc7319ba6a3af836

Maternal gluten, cereal, and dietary fiber intake during pregnancy and lactation and the risk of islet autoimmunity and type 1 diabetes in the child

Autor: Anna, Eurén, Heikki, Hyöty, Kalle, Kurppa, Jutta, Laiho, Olli, Laitinen, Jussi, Lehtonen, Katri, Lindfors, Maria, Lönnrot, Johannes, Malkamäki, Noora, Nurminen, Matti, Nykter, Sami, Oikarinen, Leena, Puustinen, Amirbabak, Sioofy-Khojine, Keijo, Viiri, Daniel, Agardh, Andrén, Aronsson Carin, Markus, Lundgren, Iida, Mäkelä, Martin, Romantschuk, Laura, Soininen, Nicolai A, Lund-Blix, Maria, Magnus, Aino-Kaisa, Rantala, Lars, Stene, Ketil, Størdal, German, Tapia, Laura, Elo, Sini, Junttila, Riitta, Lahesmaa, Johanna, Lempainen, Robert, Moulder, Omid, Rasool, Tomi, Suomi, Jorma, Toppari, Ubaid, Ullah, Riitta, Veijola, Aleksandr, Peet, Kärt, Simre, Vallo, Tillmann, Elena, Bargagli, Francesco, Dotta, Laura, Nigi, Guido, Sebastiani, Leena, Hakola, Hannu, Kiviranta, Panu, Rantakokko, Suvi M, Virtanen, Ondrej, Cinek, Eva, Fronkova, Jaroslav, Havlik, Matthieu, Molinier, Juha, Pajula, Eija, Parmes, Juha, Pärkkä, Petri, Saviranta, Peter, Ylén, Alar, Aints, Anu, Bärenson, Anne, Kirss, Ivo, Laidmäe, Astrid, Oras, Aili, Tagoma, Raivo, Uibo, Tamara, Vorobjova, Loïc, Burr, Stefano, Cattaneo, Hui, Chai-Gao, Peter, Cristofollini, Silvia, Generelli, Samantha, Paoletti, Edith, Ruth, Gabriele, Berg, Wisnu, Wicaksono, Joseph, Petrosino, Rainer, Thiel, Schmidtmann, Daniel, Rosanna, Salo, Lauri, Häme, Alexander, Berler, Korina, Papadopoulou, Hans, Bisgaard, Klaus, Bonnelykke, Sarah, Brandt, Astrid, Sevelsted, Jakob, Stokholm, Jonathan, Thorsen, Mikael, Knip, Aki, Sinkkonen, Marja, Roslund, Hakola, Leena, Lund-Blix, Nicolai A., Takkinen, Hanna-Mari, Tapanainen, Heli, Niinistö, Sari, Korhonen, Tuuli E., Stene, Lars C., Hyöty, Heikki, Toppari, Jorma, Ilonen, Jorma, Knip, Mikael, Veijola, Riitta, Virtanen, Suvi M.

Publikováno v: In Clinical Nutrition ESPEN August 2024 62:22-27

A study of 51 subtypes of peripheral blood immune cells in newly diagnosed young type 1 diabetes patients

Autor: Vallo Tillmann, Astrid Oras, Aleksandr Peet, Raivo Uibo, T Giese

Publikováno v: Clin Exp Immunol

Summary Type 1 diabetes (T1D) results from autoimmune destruction of insulin-producing beta cells in pancreatic islets. Various immune cell populations are involved in disease development and natural course. However, to our knowledge, so far there ar

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8148936fcb908446660d7f637889dfe
https://doi.org/10.1111/cei.13332

Celiac Disease in Children, Particularly with Accompanying Type 1 Diabetes, Is Characterized by Substantial Changes in the Blood Cytokine Balance, Which May Reflect Inflammatory Processes in the Small Intestinal Mucosa

Autor: Aili Tagoma, Astrid Oras, Kristi Alnek, Raivo Uibo, Oivi Uibo, Kalle Kisand, Ija Talja, Tamara Vorobjova

Publikováno v: Journal of Immunology Research, Vol 2019 (2019)
Journal of Immunology Research

Cytokines play a pivotal role in the maintenance of intestinal homeostasis inducing pro- or anti-inflammatory response and mucosal barrier function in celiac disease (CD) and type 1 diabetes (T1D). We aimed to compare the levels of pro- and anti-infl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66e7c5aeb09d5bd9f0f694cde31617fc
https://doaj.org/article/c36172974fcd425b967487396ecfc967