Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Astrid Ooms"'
Autor:
Kenichi Kimura, Astrid Ooms, Kathrin Graf-Riesen, Maithreyan Kuppusamy, Andreas Unger, Julia Schuld, Jan Daerr, Achim Lother, Caroline Geisen, Lutz Hein, Satoru Takahashi, Guang Li, Wilhelm Röll, Wilhelm Bloch, Peter F. M. van der Ven, Wolfgang A. Linke, Sean M. Wu, Pitter F. Huesgen, Jörg Höhfeld, Dieter O. Fürst, Bernd K. Fleischmann, Michael Hesse
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
An amino acid exchange (P209L) in the human co-chaperone BAG3 gives rise to severe childhood restrictive cardiomyopathy. Here the authors describe humanized transgenic mouse models which phenocopy the disease and provide insight into the pathogenic m
Externí odkaz:
https://doaj.org/article/6cdac892607d45f6a6225c942b322a42
Autor:
Astrid Ooms, Michael Hesse, Sean M. Wu, Lutz Hein, Wolfgang A. Linke, Kenichi Kimura, Achim Lother, Dieter O. Fürst, Andreas Unger, Julia Braune, Guang Li, Jörg Höhfeld, Kathrin Graf-Riesen, Jan Daerr, Bernd K. Fleischmann
Publikováno v:
Circulation Research. 125
The co-chaperone BAG3 (Bcl-2 associated athanogene 3) is strongly expressed in cross-striated muscles and plays a key role in the turnover of muscle-proteins as a member of the CASA (chaperone-assisted selected autophagy) complex. An amino acid excha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::462b8fc67db195c1de91515ffec8d726
https://doi.org/10.1161/res.125.suppl_1.466
https://doi.org/10.1161/res.125.suppl_1.466