Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Astrid Johannesson Hjelholt"'
Autor:
Mette Madsen, Henrik Støvring, Niels Jessen, Esben Thyssen Vestergaard, Kurt Kristensen, Ida Borreby Pedersen, Mads Kjolby, Astrid Johannesson Hjelholt, Ann-Margrethe Rønholt Christensen, Ditte Adolfsen, Jesper Sand Hjelle, Britta Kremke
Publikováno v:
BMJ Open, Vol 14, Iss 6 (2024)
Introduction Children and adolescents with recent-onset type 1 diabetes (T1D) commonly maintain a certain level of insulin production during the remission phase, which can last months to years. Preserving β-cell function can reduce T1D complications
Externí odkaz:
https://doaj.org/article/43be637eb1614ac797274565c63a08c0
Autor:
Astrid Johannesson Hjelholt, Cecilia Bergh, Deepak L. Bhatt, Ole Fröbert, Mads Fuglsang Kjolby
Publikováno v:
Vaccines, Vol 11, Iss 9, p 1419 (2023)
Influenza vaccines are designed to mimic natural influenza virus exposure and stimulate a long-lasting immune response to future infections. The evolving nature of the influenza virus makes vaccination an important and efficacious strategy to reduce
Externí odkaz:
https://doaj.org/article/8d988456e500461db0e4d2854395e92d
Autor:
Mai C. Arlien-Søborg, Jakob Dal, Michael Alle Madsen, Morten Lyng Høgild, Astrid Johannesson Hjelholt, Steen B. Pedersen, Niels Møller, Niels Jessen, Jens O.L. Jørgensen
Publikováno v:
EBioMedicine, Vol 75, Iss , Pp 103763- (2022)
Summary: Background: Patients with active acromegaly exhibit insulin resistance despite a lean phenotype whereas controlled disease improves insulin sensitivity and increases fat mass. The mechanisms underlying this paradox remain elusive, but growth
Externí odkaz:
https://doaj.org/article/8ec3e8c7332f442d8228529df908499a
Autor:
Astrid Johannesson Hjelholt, Kevin Y. Lee, Mai Christiansen Arlien-Søborg, Steen Bønløkke Pedersen, John J. Kopchick, Vishwajeet Puri, Niels Jessen, Jens Otto L. Jørgensen
Publikováno v:
Molecular Metabolism, Vol 29, Iss , Pp 65-75 (2019)
Objective: Growth hormone (GH) stimulates lipolysis, but the underlying mechanisms remain incompletely understood. We examined the effect of GH on the expression of lipolytic regulators in adipose tissue (AT). Methods: In a randomized, placebo-contro
Externí odkaz:
https://doaj.org/article/df977ca1ec0d4245be3b77f6148036fd
Autor:
Elin Rakvaag, Rasmus Fuglsang-Nielsen, Knud Erik Bach Knudsen, Rikard Landberg, Astrid Johannesson Hjelholt, Esben Søndergaard, Kjeld Hermansen, Søren Gregersen
Publikováno v:
Nutrients, Vol 11, Iss 9, p 2091 (2019)
Abdominal obesity is associated with elevated postprandial triglycerides (TG), an independent risk factor for cardiovascular diseases. Previous studies show that whey protein (WP) and dietary fiber may separately reduce postprandial TG. However, few
Externí odkaz:
https://doaj.org/article/2a1df2ab506940489b880ee39f2a04ac
Autor:
Morten Lyng Høgild, Astrid Johannesson Hjelholt, Jakob Hansen, Steen Bønløkke Pedersen, Niels Møller, Jørgen F P Wojtaszewski, Mogens Johannsen, Niels Jessen, Jens Otto Lunde Jørgensen
Publikováno v:
Høgild, M L, Hjelholt, A J, Hansen, J, Pedersen, S B, Møller, N, Wojtaszewski, J F P, Johannsen, M, Jessen, N & Lunde Jørgensen, J O 2023, ' Ketone Body Infusion abrogates Growth Hormone Induced Lipolysis and Insulin Resistance ', The Journal of clinical endocrinology and metabolism, vol. 108, no. 3, pp. 653-664 . https://doi.org/10.1210/clinem/dgac595
ContextExogenous ketone body administration lowers circulating glucose levels but the underlying mechanisms are uncertain.ObjectiveWe tested the hypothesis that administration of the ketone body β-hydroxybutyrate (βOHB) acutely increases insulin se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fc20c68c3b3f387aa99e20d1ebe736c
https://pure.au.dk/portal/da/publications/ketone-body-infusion-abrogates-growth-hormone-induced-lipolysis-and-insulin-resistance(ea7429e3-b1dd-45fe-a47e-1448b31bab75).html
https://pure.au.dk/portal/da/publications/ketone-body-infusion-abrogates-growth-hormone-induced-lipolysis-and-insulin-resistance(ea7429e3-b1dd-45fe-a47e-1448b31bab75).html
Autor:
Niels Møller, Jens Otto Lunde Jørgensen, Julian L. Griffin, Niels Jessen, Henriette Pilegaard, Astrid Johannesson Hjelholt, Anders Gudiksen, Steen B. Pedersen, Evelina Charidemou
Publikováno v:
Hjelholt, A J, Charidemou, E, Griffin, J L, Pedersen, S B, Gudiksen, A, Pilegaard, H, Jessen, N, Møller, N & Jørgensen, J O L 2020, ' Insulin resistance induced by growth hormone is linked to lipolysis and associated with suppressed pyruvate dehydrogenase activity in skeletal muscle : a 2x2 factorial, randomised, crossover study in human individuals ', Diabetologia, vol. 63, no. 12, pp. 2641-2653 . https://doi.org/10.1007/s00125-020-05262-w
AIMS/HYPOTHESIS: Growth hormone (GH) causes insulin resistance that is linked to lipolysis, but the underlying mechanisms are unclear. We investigated if GH-induced insulin resistance in skeletal muscle involves accumulation of diacylglycerol (DAG) a
Publikováno v:
Ugeskrift for laeger. 183(21)
This case report describes a 57-year-old male with symptoms of tardive akathisia after long-term metoclopramide treatment. As metoclopramide is a dopamine receptor antagonist, it has the potential to cause drug-induced movement disorders, including a
Autor:
John J. Kopchick, Jens Otto Lunde Jørgensen, Astrid Johannesson Hjelholt, Mai Christiansen Arlien-Søborg, Kevin Y. Lee, Niels Jessen, Steen B. Pedersen, Vishwajeet Puri
Publikováno v:
Molecular Metabolism
Hjelholt, A J, Lee, K Y, Arlien-Søborg, M C, Pedersen, S B, Kopchick, J J, Puri, V, Jessen, N & Jørgensen, J O L 2019, ' Temporal patterns of lipolytic regulators in adipose tissue after acute growth hormone exposure in human subjects : A randomized controlled crossover trial ', Molecular Metabolism, vol. 29, pp. 65-75 . https://doi.org/10.1016/j.molmet.2019.08.013
Molecular Metabolism, Vol 29, Iss, Pp 65-75 (2019)
Hjelholt, A J, Lee, K Y, Arlien-Søborg, M C, Pedersen, S B, Kopchick, J J, Puri, V, Jessen, N & Jørgensen, J O L 2019, ' Temporal patterns of lipolytic regulators in adipose tissue after acute growth hormone exposure in human subjects : A randomized controlled crossover trial ', Molecular Metabolism, vol. 29, pp. 65-75 . https://doi.org/10.1016/j.molmet.2019.08.013
Molecular Metabolism, Vol 29, Iss, Pp 65-75 (2019)
Objective Growth hormone (GH) stimulates lipolysis, but the underlying mechanisms remain incompletely understood. We examined the effect of GH on the expression of lipolytic regulators in adipose tissue (AT). Methods In a randomized, placebo-controll
Autor:
Steen B. Pedersen, Morten Hogild, Niels Møller, Niels Jessen, Bjørn Richelsen, Ann Mosegaard Bak, Astrid Johannesson Hjelholt, Amanda Bæk, Mai Christiansen Arlien-Søborg, Jens Otto Lunde Jørgensen
Publikováno v:
Hjelholt, A, Høgild, M, Bak, A M, Arlien-Søborg, M C, Bæk, A, Jessen, N, Richelsen, B, Pedersen, S B, Møller, N & Lunde Jørgensen, J O 2020, ' Growth Hormone and Obesity ', Endocrinology and Metabolism Clinics of North America, vol. 49, no. 2, pp. 239-250 . https://doi.org/10.1016/j.ecl.2020.02.009
Growth hormone (GH) exerts IGF-I dependent protein anabolic and direct lipolytic effects. Obesity reversibly suppresses GH secretion driven by elevated FFA levels, whereas serum IGF-I levels remain normal or elevated due to elevated portal insulin le
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c62a15ef7c3c7e03d284674b9919bfbd
https://pure.au.dk/portal/da/publications/growth-hormone-and-obesity(eb3746bd-be4a-42c0-9bca-638f7635c0a9).html
https://pure.au.dk/portal/da/publications/growth-hormone-and-obesity(eb3746bd-be4a-42c0-9bca-638f7635c0a9).html