Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Astrid Hoebertz"'
Autor:
Erwin F. Wagner, Candace E. Elliott, Astrid Hoebertz, Silvia Marino, Bettina Wagner, Maria Sibilia, Wolfram Jochum
Publikováno v:
Development (Cambridge, England). 143(24)
There was an error published in Development 130 , [4515-4525][1]. In Fig. 6, owing to an error in figure assembly during preparation of the proofs, the incorrect image (a duplication of panel D) was displayed in panel G. The corrected figure appears
Autor:
Niamh Keon, Astrid Hoebertz, Marina Schorpp-Kistner, Peter Angel, Florian A. Karreth, Robert Eferl, Lukas Kenner, Erwin F. Wagner, F. Timo Beil, Agnieszka P. Szremska, Harald Scheuch, Michael Amling
Publikováno v:
The Journal of Cell Biology
Because JunB is an essential gene for placentation, it was conditionally deleted in the embryo proper. JunBDelta/Delta mice are born viable, but develop severe low turnover osteopenia caused by apparent cell-autonomous osteoblast and osteoclast defec
Autor:
Bettina Wagner, Astrid Hoebertz, Candace E. Elliott, Maria Sibilia, Erwin F. Wagner, Silvia Marino, Wolfram Jochum
Publikováno v:
Development. 130:4515-4525
Mice lacking the epidermal growth factor receptor (EGFR) develop epithelial defects and a neurodegenerative disease and die within the first month of birth. By employing a conditional knock-in approach using the human EGFR cDNA mice humanised for EGF
Autor:
Astrid Hoebertz, Latifa Bakiri, Colin L. Stewart, Erwin F. Wagner, Vukoslav Komnenovic, Michael Amling, Aline Bozec, Matthias Priemel, Robert Eferl, Arndt F. Schilling, Harald Scheuch
Publikováno v:
Nature. 454(7201)
Osteoclasts are cells that resorb bone. Too many of them, and osteoporosis — a common metabolic disorder of the skeleton — can result, as well as several other diseases. Although the protein c-Fos plays an essential part in the formation of osteo
Publikováno v:
Development (Cambridge, England). 131(22)
The Fos-related AP1 transcription factor Fra2 (encoded by Fosl2)is expressed in various epithelial cells as well as in cartilaginous structures. We studied the role of Fra2 in cartilage development. The absence of Fra2 in embryos and newborns leads t
Autor:
Florian A. Karreth, Robert Eferl, Martina Rath, Erwin F. Wagner, Lukas Kenner, Astrid Hoebertz, Arndt F. Schilling, Michael Amling
Publikováno v:
The EMBO journal. 23(14)
Ectopic expression of the transcription factor Fra-1 in transgenic mice leads to osteosclerosis, a bone disorder characterized by increased bone mass. The molecular basis for this phenotype is unknown and Fra-1 functions cannot be studied by a conven
Autor:
Astrid, Hoebertz, Timothy R, Arnett
Publikováno v:
Methods in molecular medicine. 80
Autor:
Timothy R. Arnett, Daniel C. Gibbons, Jennifer C. Utting, Isabel R. Orriss, Astrid Hoebertz, Martin Rosendaal, Sajeda Meghji
Publikováno v:
Journal of Cellular Physiology; Jul2003, Vol. 196 Issue 1, p2-8, 7p
Autor:
Astrid Hoebertz, Erwin F. Wagner, Aline Bozec, Florian A. Karreth, Michael Amling, Robert Eferl, Matthias Priemel, Arndt F. Schilling, Harald Scheuch
Publikováno v:
Bone. 38:9
Publikováno v:
Arthritis Research & Therapy. 5:49
Fos proteins such as Fos, FosB, Fra-1 and Fra-2 are key regulators of bone development. Transgenic mice expressing Fos develop osteoblastic bone tumors, whereas mice lacking Fos (Fos-/-) are osteopetrotic and lack bone-resorbing osteoclasts [1]. The