Zobrazeno 1 - 10
of 113
pro vyhledávání: '"Astrid Gruber"'
Autor:
Hareth Nahi, Michael Chrobok, Charlotte Gran, Johan Lund, Astrid Gruber, Gösta Gahrton, Per Ljungman, Arnika Kathleen Wagner, Evren Alici
Publikováno v:
PLoS ONE, Vol 14, Iss 2, p e0211927 (2019)
Treatment with Daratumumab (Dara), a monoclonal anti-CD38 antibody of IgG1 subtype, is effective in patients with multiple myeloma (MM). However, Dara also impairs the cellular immunity, which in turn may lead to higher susceptibility to infections.
Externí odkaz:
https://doaj.org/article/8c5c0ffa5f5243c9a13885e7703ab73b
Publikováno v:
IEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing, Vol 9, Iss 3, Pp 1047-1057 (2016)
Since 2010, TanDEM-X and its twin satellite TerraSAR-X fly in a close orbit formation and form a single-pass synthetic aperture radar (SAR) interferometer. The formation was established to acquire a global high-precision digital elevation model (DEM)
Externí odkaz:
https://doaj.org/article/d8faebf4945f4ad98edb0931dffc8b60
Autor:
Irina Cornaciu, Andras Boeszoermenyi, Hanna Lindermuth, Harald M Nagy, Ines K Cerk, Catharina Ebner, Barbara Salzburger, Astrid Gruber, Martina Schweiger, Rudolf Zechner, Achim Lass, Robert Zimmermann, Monika Oberer
Publikováno v:
PLoS ONE, Vol 6, Iss 10, p e26349 (2011)
Adipose triglyceride lipase (ATGL) is the rate-limiting enzyme of lipolysis. ATGL specifically hydrolyzes triacylglycerols (TGs), thereby generating diacylglycerols and free fatty acids. ATGL's enzymatic activity is co-activated by the protein compar
Externí odkaz:
https://doaj.org/article/28a603b136c34ca58a6e7de50c6a8030
Autor:
Hans E. Johnsen, Bo Björkstrand, Tobias W. Klausen, Kari Remes, Astrid Gruber, Lene M. Knudsen, Olav J. Bergmann, Stig Lenhoff
Publikováno v:
Hematology Reports, Vol 1, Iss 1, Pp e2-e2 (2009)
Autologous stem cell transplantation is still considered the standard of care in young patients with multiple myeloma (MM). This disease is the most common indication for high-dose therapy (HDT) supported by hematopoietic stem-cell transplantation an
Externí odkaz:
https://doaj.org/article/3ba753057cae4299b0d208e667b731b2
Autor:
Theocharis Panaretakis, Karin Vanderkerken, Magnus Björkholm, Fredrik Celsing, Dan Grandér, Helena Jernberg-Wiklund, Boris Zhivotovsky, Anders Österborg, Edward Laane, Maria Panzar, Georgia Kokaraki, Per Johnsson, Astrid Gruber, Qiao Li, Charlotte Fristedt, Hendrik De Raeve, Pedram Kharaziha
PDF file - 106K, Immunoblot analysis of the indicated proteins in U-266 and LP-1 pre-treated with 10 muM CQ, 10 muM zVAD.fmk or 4 muM MG132 (for 4h) followed by 10 mu M Sor for 24h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d708b36ecfb7c5123453e60dd89c41d4
https://doi.org/10.1158/0008-5472.22393196.v1
https://doi.org/10.1158/0008-5472.22393196.v1
Autor:
Theocharis Panaretakis, Karin Vanderkerken, Magnus Björkholm, Fredrik Celsing, Dan Grandér, Helena Jernberg-Wiklund, Boris Zhivotovsky, Anders Österborg, Edward Laane, Maria Panzar, Georgia Kokaraki, Per Johnsson, Astrid Gruber, Qiao Li, Charlotte Fristedt, Hendrik De Raeve, Pedram Kharaziha
PDF file - 26K, The indicated myeloma cell lines were treated with 10 muM Sor for 24h and cell cycle distribution was analysed by NucleoCounter NC-3000 (Chemometec).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::346a96b76efa6a16928cbabc549badb2
https://doi.org/10.1158/0008-5472.22393199.v1
https://doi.org/10.1158/0008-5472.22393199.v1
Autor:
Theocharis Panaretakis, Karin Vanderkerken, Magnus Björkholm, Fredrik Celsing, Dan Grandér, Helena Jernberg-Wiklund, Boris Zhivotovsky, Anders Österborg, Edward Laane, Maria Panzar, Georgia Kokaraki, Per Johnsson, Astrid Gruber, Qiao Li, Charlotte Fristedt, Hendrik De Raeve, Pedram Kharaziha
PDF file - 36K, A, Quantitative analysis of Annexin V/PI positive murine 5T33MMvitro cells treated the indicated concentrations of sorafenib for 24h and 48h; B, Immunoblot analysis of the indicated proteins from the 5T33MMvitro cell line treated with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6da9d4edfd158c29e96729acacb6ea11
https://doi.org/10.1158/0008-5472.22393193
https://doi.org/10.1158/0008-5472.22393193
Autor:
Birgit Wessel, Martin Huber, Christian Wohlfart, Ursula Marschalk, Adina Bertram, Felix Reuß, Sahra Abdullahi, Isabel Georg, Achim Roth, Nicole Osterkamp, Astrid Gruber
We present the generation and validation of an updated version of the TanDEM-X digital elevation model (DEM) of Antarctica: the TanDEM-X PolarDEM 90 m of Antarctica. Improvements compared to the global TanDEM-X DEM version comprise filling gaps with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bad162867e8a1dfca0c0275005d76e4
https://tc.copernicus.org/articles/15/5241/2021/
https://tc.copernicus.org/articles/15/5241/2021/
Autor:
Astrid Gruber, Markus Hansson, Agneta Swedin, Johan Lund, Gösta Gahrton, Adil Doganay Duru, Lucia Ahlberg, Anders Waage, Ulf-Henrik Mellqvist, Peter Gimsing, Birgitta Lauri, Mats Hardling, Ulf Christian Frølund, Karin Forsberg, Erik Holmberg, Evren Alici, Conny Carlsson, Hareth Nahi, Annette Juul Vangsted, Cecilie Blimark
Publikováno v:
Cancer Medicine
Lund, J, Gruber, A, Lauri, B, Duru, A D, Blimark, C, Swedin, A, Hansson, M, Forsberg, K, Ahlberg, L, Carlsson, C, Waage, A, Gimsing, P, Vangsted, A J, Frølund, U, Holmberg, E, Gahrton, G, Alici, E, Hardling, M, Mellqvist, U-H & Nahi, H 2018, ' Lenalidomide versus lenalidomide + dexamethasone prolonged treatment after second-line lenalidomide + dexamethasone induction in multiple myeloma ', Cancer Medicine, vol. 7, no. 6, pp. 2256-2268 . https://doi.org/10.1002/cam4.1422
Lund, J, Gruber, A, Lauri, B, Duru, A D, Blimark, C, Swedin, A, Hansson, M, Forsberg, K, Ahlberg, L, Carlsson, C, Waage, A, Gimsing, P, Vangsted, A J, Frølund, U, Holmberg, E, Gahrton, G, Alici, E, Hardling, M, Mellqvist, U-H & Nahi, H 2018, ' Lenalidomide versus lenalidomide + dexamethasone prolonged treatment after second-line lenalidomide + dexamethasone induction in multiple myeloma ', Cancer Medicine, vol. 7, no. 6, pp. 2256-2268 . https://doi.org/10.1002/cam4.1422
Lenalidomide (Len) plus dexamethasone (Dex) is approved for the treatment of relapsed or refractory multiple myeloma (RRMM). It is possible that single‐agent Len may be effective as prolonged treatment regimen in RRMM once patients demonstrate an i
Autor:
Evren Alici, Johan Lund, Conny Carlsson, Cecilie Blimark, Hareth Nahi, Astrid Gruber, Ulf-Henrik Mellqvist, Ingrid Jakobsen Falk, Agneta Swedin, Kourosh Lotfi, Lucia Ahlberg, Mats Hardling, Karin Forsberg, Henrik Gréen, Birgitta Lauri
Publikováno v:
Cancer Chemotherapy and Pharmacology
Purpose Despite therapeutic advances, patients with multiple myeloma (MM) continue to experience disease relapse and treatment resistance. The gene ABCB1 encodes the drug transporter P-glycoprotein, which confers resistance through drug extrusion acr