Výsledky vyhledávání - "Astrid Grosche"

Akademický článek

Advancing peristalsis deciphering in mouse small intestine by multi-parameter tracking

Autor: Anusree Sasidharan, Breman Anil Peethambar, Keerthi Santhosh Kumar, Ashok V. Kumar, Arun Hiregange, Neil Fawkes, James F. Collins, Astrid Grosche, Sadasivan Vidyasagar

Publikováno v: Communications Biology, Vol 6, Iss 1, Pp 1-15 (2023)

Abstract Assessing gastrointestinal motility lacks simultaneous evaluation of intraluminal pressure (ILP), circular muscle (CM) and longitudinal muscle (LM) contraction, and lumen emptying. In this study, a sophisticated machine was developed that sy

Externí odkaz: https://doaj.org/article/25cae9c107664f3b995093b4aaa2006d

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Akademický článek

Select amino acids recover cytokine-altered ENaC function in human bronchial epithelial cells.

Autor: Anusree Sasidharan, Astrid Grosche, Xiaodong Xu, T Bernard Kinane, Damiano Angoli, Sadasivan Vidyasagar

Publikováno v: PLoS ONE, Vol 19, Iss 7, p e0307809 (2024)

The airway epithelium plays a pivotal role in regulating mucosal immunity and inflammation. Epithelial barrier function, homeostasis of luminal fluid, and mucociliary clearance are major components of mucosal defense mechanisms. The epithelial sodium

Externí odkaz: https://doaj.org/article/f7be3765adc842a7b1f1f643a8531d4f

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Akademický článek

Amino acid solution mitigates hypothermia response and intestinal damage following exertional heat stroke in male mice

Autor: Michelle A. King, Astrid Grosche, Shauna M. Ward, Jermaine A. Ward, Anusree Sasidharan, Thomas A. Mayer, Mark L. Plamper, Xiaodong Xu, Matthew D. Ward, Thomas L. Clanton, Sadasivan Vidyasagar

Publikováno v: Physiological Reports, Vol 11, Iss 10, Pp n/a-n/a (2023)

Abstract Increased gut permeability is implicated in the initiation and extent of the cytokine inflammatory response associated with exertional heat stroke (EHS). The primary objective of this study was to determine if a five amino acid oral rehydrat

Externí odkaz: https://doaj.org/article/3d38e6261ba14746adbd931dad9aa400

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An Amino Acid–Based Oral Rehydration Solution Regulates Radiation-Induced Intestinal Barrier Disruption in Mice

Autor: Liangjie Yin, Shanshan Lin, Paul Okunieff, Lauren Vaught, Sadasivan Vidyasagar, Reshu Gupta, Xiaodong Xu, Jing Guo, Astrid Grosche

Publikováno v: The Journal of Nutrition. 150:1100-1108

BACKGROUND Radiotherapy inadvertently affects gastrointestinal (GI) epithelial cells, causing intestinal barrier disruption and increased permeability. OBJECTIVE We examined the effect of amino acid-based oral rehydration solution (AA-ORS) on radiati

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d28a29f93a892fa9648210d197d055e9
https://doi.org/10.1093/jn/nxaa025

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Intestinal DMT1 Is Essential for Optimal Assimilation of Dietary Copper in Male and Female Mice with Iron-Deficiency Anemia

Autor: Shireen R.L. Flores, James F. Collins, Astrid Grosche, Regina R. Woloshun, Caglar Doguer, Jung-Heun Ha, Ping Xiang, Sadasivan Vidyasagar, Xiaoyu Wang

Publikováno v: The Journal of Nutrition. 148:1244-1252

BACKGROUND: Divalent metal-ion transporter 1 (DMT1) may transport copper, but studies to date on this topic have been equivocal. Previously, an ex vivo experiment showed that intestinal copper transport was impaired in Dmt1-mutant Belgrade rats. OBJE

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ed4152a4a8aa54ef0ba04dc7251b561
https://doi.org/10.1093/jn/nxy111

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