Gingival fibroblasts produce paracrine signals that affect osteoclastogenesis in vitro

Autor: Solen Novello, Ton Schoenmaker, Teun J. de Vries, Behrouz Zandieh Doulabi, Astrid D. Bakker, Marja L. Laine, Ineke D.C. Jansen

Publikováno v: Bone Reports, Vol 22, Iss , Pp 101798- (2024)

In periodontitis, gingival fibroblasts (GF) appear to produce a multitude of paracrine factors. However, the influence of GF-derived soluble factors on osteoclastogenesis remains unclear. In this case study, production of paracrine factors by GF was

Externí odkaz: https://doaj.org/article/35a6187bd3644276a5dd88494107e699

Shear loaded osteocyte-like-cells affect epithelial and mesenchymal gene expression in DU145 prostate cancer cells, while decreasing their invasion in vitro

Autor: Victor J.B. van Santen, Jianfeng Jin, Jolanda M.A. Hogervorst, Astrid D. Bakker

Publikováno v: Biochemical and Biophysical Research Communications, 646, 70-77. Academic Press Inc.
van Santen, V J B, Jin, J, Hogervorst, J M A & Bakker, A D 2023, ' Shear loaded osteocyte-like-cells affect epithelial and mesenchymal gene expression in DU145 prostate cancer cells, while decreasing their invasion in vitro ', Biochemical and Biophysical Research Communications, vol. 646, pp. 70-77 . https://doi.org/10.1016/j.bbrc.2023.01.066

Once prostate cancer (PC) metastasizes towards bone the 5-year survival rates drop with 70%, but it is largely unknown why. Bone is continuously mechanically loaded, which likely modulates the paracrine signaling from osteocytes towards PC cells to a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e70726434f56d5bbf1cc0a464229b37
https://hdl.handle.net/1871.1/2412e453-ce06-4699-b471-1d2d618dd2c0

Fluid shear stress-induced mechanotransduction in myoblasts

Autor: Mohammad Haroon, Niek G.C. Bloks, Louise Deldicque, Katrien Koppo, Hadi Seddiqi, Astrid D. Bakker, Jenneke Klein-Nulend, Richard T. Jaspers

Publikováno v: Experimental cell research, Vol. 417, no.1, p. 113204 (2022)
Haroon, M, Bloks, N G C, Deldicque, L, Koppo, K, Seddiqi, H, Bakker, A D, Klein-Nulend, J & Jaspers, R T 2022, ' Fluid shear stress-induced mechanotransduction in myoblasts : Does it depend on the glycocalyx? ', Experimental Cell Research, vol. 417, no. 1, 113204, pp. 1-13 . https://doi.org/10.1016/j.yexcr.2022.113204
Experimental Cell Research, 417(1):113204, 1-13. Academic Press Inc.
Experimental Cell Research, 417(1):113204. Academic Press Inc.

Muscle stem cells (MuSCs) are involved in muscle maintenance and regeneration. Mechanically loaded MuSCs within their native niche undergo tensile and shear deformations, but how MuSCs sense mechanical stimuli and translate these into biochemical sig

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39657a6875d6595563a888640fb201c3
https://research.vu.nl/en/publications/c68c4533-4e87-40a9-88a9-ef4ebf52840f

Accuracy and reproducibility of mouse cortical bone microporosity as quantified by desktop microcomputed tomography.

Autor: Haniyeh Hemmatian, Michaël R Laurent, Samaneh Ghazanfari, Dirk Vanderschueren, Astrid D Bakker, Jenneke Klein-Nulend, G Harry van Lenthe

Publikováno v: PLoS ONE, Vol 12, Iss 8, p e0182996 (2017)

Bone's microporosity plays important roles in bone biology and bone mechanical quality. In this study, we explored the accuracy and reproducibility of nondestructive desktop μCT for 3D visualization and subsequent morphometric analysis of mouse cort

Externí odkaz: https://doaj.org/article/2e61b3934e904787bf30aa6ab2a55857

Temporomandibular joint synovial chondromatosis

Autor: Zhiqiang Song, Shanshan Yuan, Junjie Liu, Astrid D. Bakker, Jenneke Klein-Nulend, Janak L. Pathak, Qingbin Zhang

Publikováno v: Song, Z, Yuan, S, Liu, J, Bakker, A D, Klein-Nulend, J, Pathak, J L & Zhang, Q 2022, ' Temporomandibular joint synovial chondromatosis : An analysis of 7 cases and literature review ', Science Progress, vol. 105, no. 3, pp. 1-12 . https://doi.org/10.1177/00368504221115232
Science Progress, 105(3), 1-12. Science Reviews Ltd

Objective: To investigate the diagnosis and treatment procedure of synovial chondromatosis (SC) of the temporomandibular joint (TMJ). Methods: Clinical features, imaging features, surgical methods, and prognosis of 7 patients with SC of the TMJ were

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b0ef2f7c23024c897ee6672be12382c
https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85134556695&origin=inward