Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Astrid Clarke"'
Autor:
Hailing Lu, Brian P O’Connor, Ryan A Heiser, Jason D Berndt, Michelle L Ulrich, Bryan M Grogan, Reice D James, Melissa Conerly, Astrid Clarke, Kevin J Hamblett
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/c709d4b04ff94a1e845877d6feb9447b
Publikováno v:
Inflammatory Bowel Diseases. 29:S80-S81
BACKGROUND Inflammatory bowel disease (IBD) causes T cell infiltration of the intestinal mucosa, but the heterogeneity of these cells is not understood at a clonal level. The drug vedolizumab is believed to treat IBD by blocking the entry of circulat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ed444c7bd29885b09ecfca3f779c4d7
https://doi.org/10.1093/ibd/izac247.154
https://doi.org/10.1093/ibd/izac247.154
Autor:
Lord, James D., Shows, Donna, Kongala, Venkata Ramya, Hindmarch, Duncan C., Boden, Elisa K., Astrid, Clarke S.
Publikováno v:
In Gastroenterology 18-21 May 2024 166(5) Supplement:S
Autor:
Elisa Ten Hacken, Zeev Estrov, Kapil N. Bhalla, Astrid Clarke, Mariela Sivina, Philip A. Thompson, Michael J. Keating, Ekaterina Kim, William G. Wierda, Nitin Jain, Alessandra Ferrajoli, Jan A. Burger
Publikováno v:
Leukemia
Despite major improvements in treatment outcome with novel targeted therapies, such as the Bruton tyrosine kinase (BTK) inhibitor ibrutinib, chronic lymphocytic leukemia (CLL) remains incurable in the majority of patients. Activation of PI3K, NF-κB,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4710a87d8de9f51f4a12ca92f9bb2531
https://doi.org/10.1038/s41375-019-0682-7
https://doi.org/10.1038/s41375-019-0682-7
Akademický článek
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Autor:
Vanessa Gorney, Sandra Bonne-Annee, Jean Zhou, Bing Lu, Qin Yue, Bernard Murray, Kevin Currie, Astrid Clarke
Publikováno v:
Gastroenterology. 162:S-515
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2f91f8938b1ffe44d15c6281fc6b6a16
https://doi.org/10.1016/s0016-5085(22)61224-1
https://doi.org/10.1016/s0016-5085(22)61224-1
Publikováno v:
Gastroenterology. 158:S-1212
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::47997d0a3a9304188d2c2aa72f78df40
https://doi.org/10.1016/s0016-5085(20)33690-8
https://doi.org/10.1016/s0016-5085(20)33690-8
Publikováno v:
G3: Genes|Genomes|Genetics
The acetyltransferase Esa1 is essential in the yeast Saccharomyces cerevisiae and plays a critical role in multiple cellular processes. The most well-defined targets for Esa1 are lysine residues on histones. However, an increasing number of nonhiston
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b7b6146ab91704d5067226c67a510ac
https://doi.org/10.1534/g3.112.003558
https://doi.org/10.1534/g3.112.003558
Publikováno v:
G3
G3: Genes|Genomes|Genetics
G3: Genes|Genomes|Genetics
The Shugoshin (Sgo) protein family helps to ensure proper chromosome segregation by protecting cohesion at the centromere by preventing cleavage of the cohesin complex. Some Sgo proteins also influence other aspects of kinetochore-microtubule attachm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c244169bd7c7b829d48dd9d47834832
https://orcid.org/0000-0003-1993-0702
https://orcid.org/0000-0003-1993-0702
Autor:
David G. Breckenridge, Thomas Kenney, Daniel B. Tumas, Astrid Clarke, Stacey Tannheimer, Jamie Bates, Saritha Kusam
Publikováno v:
Blood. 128:5104-5104
Introduction: GS-5829 is a potent and selective inhibitor of the bromodomain and extra-terminal (BET) family of proteins. BET proteins regulate the transcription of key oncogenes including MYC, resulting in cancer cell growth (Yang Z. et. al. Mol Cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b59614438e7f85fbc71207bd455db57b
https://doi.org/10.1182/blood.v128.22.5104.5104
https://doi.org/10.1182/blood.v128.22.5104.5104