Zobrazeno 1 - 10
of 58
pro vyhledávání: '"Astrid, Liedert"'
Autor:
Jan-Moritz Ramge, Chen Xiangxu, Verena Fischer, Melanie Haffner-Luntzer, Jan Tuckermann, Karin Scharfetter-Kochanek, Anita Ignatius, Astrid Liedert
Publikováno v:
Bone Reports, Vol 14, Iss , Pp 100775- (2021)
Externí odkaz:
https://doaj.org/article/5fdf0de92a804b929160a93ecd89d72d
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 8 (2020)
Bone is a mechanosensitive tissue for which mechanical stimuli are crucial in maintaining its structure and function. Bone cells react to their biomechanical environment by activating molecular signaling pathways, which regulate their proliferation,
Externí odkaz:
https://doaj.org/article/234257f0593c498aa47381c00dfda9bc
Publikováno v:
European Journal of Medical Research, Vol 22, Iss 1, Pp 1-11 (2017)
Abstract Background Fracture healing is known to be delayed in postmenopausal, osteoporotic females under oestrogen-deficient conditions. Confirming this, experimental studies demonstrated impaired callus formation in ovariectomised animals. Oestroge
Externí odkaz:
https://doaj.org/article/488c5bc4aa7840ec8a3bf71578a98a51
Autor:
Esther Wehrle, Astrid Liedert, Aline Heilmann, Tim Wehner, Ronny Bindl, Lena Fischer, Melanie Haffner-Luntzer, Franz Jakob, Thorsten Schinke, Michael Amling, Anita Ignatius
Publikováno v:
Disease Models & Mechanisms, Vol 8, Iss 1, Pp 93-104 (2015)
Fracture healing is impaired in aged and osteoporotic individuals. Because adequate mechanical stimuli are able to increase bone formation, one therapeutical approach to treat poorly healing fractures could be the application of whole-body vibration,
Externí odkaz:
https://doaj.org/article/fb30b52c1fc14355a952e84ac998a367
Autor:
Stephanie Bergdolt, Anna Kovtun, Yvonne Hägele, Astrid Liedert, Thorsten Schinke, Michael Amling, Markus Huber-Lang, Anita Ignatius
Publikováno v:
PLoS ONE, Vol 12, Iss 6, p e0179512 (2017)
The anaphylatoxin receptor C5aR1 plays an important role not only in innate immune responses, but also in bone metabolism and fracture healing, being highly expressed on immune and bone cells, including osteoblasts and osteoclasts. C5aR1 induces oste
Externí odkaz:
https://doaj.org/article/77bcb5753f0644aebe52ca503de24622
Autor:
Melanie Haffner-Luntzer, Julia Kemmler, Verena Heidler, Katja Prystaz, Thorsten Schinke, Michael Amling, Anna Kovtun, Anna E Rapp, Anita Ignatius, Astrid Liedert
Publikováno v:
PLoS ONE, Vol 11, Iss 7, p e0159278 (2016)
The heparin-binding growth and differentiation factor midkine (Mdk) is proposed to negatively regulate osteoblast activity and bone formation in the adult skeleton. As Mdk-deficient mice were protected from ovariectomy (OVX)-induced bone loss, this f
Externí odkaz:
https://doaj.org/article/1c17257ca9324cfd979d1e405be25b4e
Autor:
Melanie Haffner-Luntzer, Aline Heilmann, Anna Elise Rapp, Simon Beie, Thorsten Schinke, Michael Amling, Anita Ignatius, Astrid Liedert
Publikováno v:
PLoS ONE, Vol 9, Iss 12, p e116282 (2014)
The growth and differentiation factor midkine (Mdk) plays an important role in bone development and remodeling. Mdk-deficient mice display a high bone mass phenotype when aged 12 and 18 months. Furthermore, Mdk has been identified as a negative regul
Externí odkaz:
https://doaj.org/article/5861f873763a481785f4823453b3fba9
Autor:
Astrid Liedert, Viktoria Röntgen, Thorsten Schinke, Peggy Benisch, Regina Ebert, Franz Jakob, Ludger Klein-Hitpass, Jochen K Lennerz, Michael Amling, Anita Ignatius
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e103250 (2014)
The canonical Wnt/β-catenin pathway plays a key role in the regulation of bone remodeling in mice and humans. Two transmembrane proteins that are involved in decreasing the activity of this pathway by binding to extracellular antagonists, such as Di
Externí odkaz:
https://doaj.org/article/d07ae21fecbd41798f58a7610da764ba
Autor:
Aline Heilmann, Thorsten Schinke, Ronny Bindl, Tim Wehner, Anna Rapp, Melanie Haffner-Luntzer, Claudia Nemitz, Astrid Liedert, Michael Amling, Anita Ignatius
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e84232 (2013)
Wnt signaling is a key regulator of bone metabolism and fracture healing. The canonical Wnt/β-catenin pathway is regarded as the dominant mechanism, and targeting this pathway has emerged as a promising strategy for the treatment of osteoporosis and
Externí odkaz:
https://doaj.org/article/4f1e5ff611a745c59d528d3817ec24fc
Autor:
Tim Rolvien, Laura Brylka, Michaela Schweizer, David J. Beech, Astrid Liedert, Udo Schumacher, Gretl Hendrickx, Mona Neven, Melanie Haffner-Luntzer, Eva Pawlus, Anita Ignatius, Timur A. Yorgan, Verena Fischer, Michael Amling, Anke Baranowsky, Thorsten Schinke, Kroge Simon von
Publikováno v:
Journal of bone and mineral research
The skeleton is a dynamic tissue continuously adapting to mechanical stimuli. Although matrix-embedded osteocytes are considered as the key mechanoresponsive bone cells, all other skeletal cell types are principally exposed to macroenvironmental and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62daaa241566d0886578a48bbb42fb1b
https://lirias.kuleuven.be/handle/20.500.12942/710935
https://lirias.kuleuven.be/handle/20.500.12942/710935
