Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Astressin-B"'
Akademický článek
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Autor:
Jean Rivier
Publikováno v:
Current Molecular Pharmacology. 10
It is noteworthy that thirty three years of efforts in corticotropin releasing factor (CRF) research by academia and the pharmaceutical industry resulted in several thousand papers and patents, yet little progress has been made to identify and market
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07e0f26a0fb654c73b49886fd7945aa5
https://doi.org/10.2174/1874467210666170110112914
https://doi.org/10.2174/1874467210666170110112914
Autor:
Florence P. Varodayan, George Luu, Christopher S. Oleata, Dean Kirson, Diego Correia, Paul Schweitzer, Sophia Khom, Marisa Roberto
Publikováno v:
Neuropharmacology. 125
Corticotropin-releasing factor (CRF) signaling in the central nucleus of the amygdala (CeA) is hypothesized to drive the development of alcohol dependence, as it regulates ethanol intake and several anxiogenic behaviors linked to withdrawal. Excitato
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2da68aa361d400df66d5570b0731efd6
https://pubmed.ncbi.nlm.nih.gov/28807676
https://pubmed.ncbi.nlm.nih.gov/28807676
Autor:
Catherine Rivier, Jean Rivier
Publikováno v:
Frontiers in Neuroendocrinology. 35:161-170
Elusive for more than half a century, corticotropin-releasing factor (CRF) was finally isolated and characterized in 1981 from ovine hypothalami and shortly thereafter, from rat brain. Thirty years later, much has been learned about the function and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ba5e789e74b6ba635dae705b40988d2
https://doi.org/10.1016/j.yfrne.2013.10.006
https://doi.org/10.1016/j.yfrne.2013.10.006
Autor:
J. Gulyas, Judit Erchegyi, Charleen Miller, Seiichi Yakabi, Hiroshi Karasawa, Marilyn H. Perrin, Catherine Rivier, William Low, Joan Vaughan, Wolfgang H. Fischer, Lixin Wang, Manoj P. Samant, Yvette Taché, Kathy A. Lewis, Jean Rivier, Cynthia J. Donaldson
Publikováno v:
Journal of medicinal chemistry, vol 59, iss 3
CRF mediates numerous stress-related endocrine, autonomic, metabolic, and behavioral responses. We present the synthesis and chemical and biological properties of astressin B analogues {cyclo(30-33)[D-Phe(12),Nle(21,38),C(α)MeLeu(27,40),Glu(30),Lys(
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b91daf36fc1e87be7c63c294749f9b4c
https://escholarship.org/uc/item/6j08p9tn
https://escholarship.org/uc/item/6j08p9tn
Publikováno v:
Journal of the American Chemical Society. 129:16102-16114
Members of the corticoliberin family include the corticotropin releasing factors (CRFs), sauvagine, the urotensins, and urocortin 1 (Ucn1), which bind to both the CRF receptors CRF-R1 and CRF-R2, and the urocortins 2 (Ucn2) and 3 (Ucn3), which are se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb952827a89d8a75439b0239fbd4d4d7
https://doi.org/10.1021/ja0760933
https://doi.org/10.1021/ja0760933
Autor:
Andrew Luckey, David Heber, Lixin Wang, Almaas Shaikh, Yvette Taché, Nicole R. Basa, David H. St-Pierre
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 291:G611-G620
LPS injected intraperitoneally decreases fasted plasma levels of ghrelin at 3 h postinjection in rats. We characterized the inhibitory action of LPS on plasma ghrelin and whether exogenous ghrelin restores LPS-induced suppression of food intake and g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ffd3a626a87559b297ba9cb562e05f5
https://doi.org/10.1152/ajpgi.00533.2005
https://doi.org/10.1152/ajpgi.00533.2005
Akademický článek
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Publikováno v:
Neuropsychopharmacology. 29:1112-1121
The present study compares the activity of two chemically distinct corticotropin-releasing hormone (CRH) antagonists at the level of the pituitary gland in rhesus monkeys, using exogenous CRH-stimulated increases in adrenocorticotropin (ACTH) and cor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1c5418c0c3e27f6a07afb2931eb1cca
https://doi.org/10.1038/sj.npp.1300410
https://doi.org/10.1038/sj.npp.1300410
Publikováno v:
Endocrinology. 144:2396-2403
We investigated the contribution of corticotropin-releasing factor (CRF) receptors types 1 and 2 (CRF(1) and CRF(2)) in mediating the ACTH response to shock, alcohol injection, or endotoxemia in the rat. Peptidic (Astressin B and Astressin(2)-B) and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4bbefa1abb9cd96fe17f606663eeafa
https://doi.org/10.1210/en.2002-0117
https://doi.org/10.1210/en.2002-0117