Zobrazeno 1 - 10
of 122
pro vyhledávání: '"Astra M Liepa"'
Publikováno v:
Current Oncology, Vol 30, Iss 2, Pp 1869-1881 (2023)
The decision to treat advanced gastroesophageal cancers (GECs) with targeted therapy and immunotherapy is based on key biomarker expression (human epidermal growth factor receptor 2 (HER2), programmed cell death-ligand 1 (PD-L1), microsatellite insta
Externí odkaz:
https://doaj.org/article/b62f2e6a705a40fc8ae2a699bf007a1d
Autor:
Andrea Necchi, Hiroyuki Nishiyama, Nobuaki Matsubara, Jae-Lyun Lee, Daniel P. Petrylak, Ronald de Wit, Alexandra Drakaki, Astra M. Liepa, Huzhang Mao, Katherine Bell-McGuinn, Thomas Powles
Publikováno v:
BMC Urology, Vol 20, Iss 1, Pp 1-11 (2020)
Abstract Background To evaluate patient-reported outcomes with ramucirumab plus docetaxel, a regimen which improved progression-free survival in platinum-refractory advanced urothelial carcinoma (aUC). Methods RANGE—a randomized, double-blinded, ph
Externí odkaz:
https://doaj.org/article/4a6e35606be743dd920d27ac9dcff020
Autor:
Donald M. Bushnell, MA, Thomas M. Atkinson, PhD, Kelly P. McCarrier, PhD, Astra M. Liepa, PharmD, Kendra P. DeBusk, PhD, Stephen Joel Coons, PhD
Publikováno v:
Current Therapeutic Research, Vol 95, Iss , Pp 100642- (2021)
ABSTRACT: Background: The Non–Small Cell Lung Cancer Symptom Assessment Questionnaire (NSCLC-SAQ) was developed to incorporate the patient's perspective into evaluation of clinical benefit in advanced non–small cell lung cancer trials and meet re
Externí odkaz:
https://doaj.org/article/8a6efa162794453a945beaf5008c4499
Autor:
Johannes Clouth, Astra M. Liepa, Guido Moeser, Heiko Friedel, Magdalena Bernzen, Jörg Trojan, Elena Garal-Pantaler
Publikováno v:
Health Economics Review, Vol 8, Iss 1, Pp 1-10 (2018)
Abstract Objective To estimate both the number of patients with hepatocellular carcinoma (HCC) eligible annually for second-line therapy following sorafenib in Germany and the healthcare costs accrued by patients meeting eligibility criteria. Methods
Externí odkaz:
https://doaj.org/article/47474189adb2481bba88e0a6e2808703
Publikováno v:
Future Oncology.
Aim: To describe real-world treatment sequences of ramucirumab relative to immune checkpoint inhibitors (ICIs) in patients with advanced gastroesophageal cancer. Methods: Retrospective, observational study including adult patients treated with ramuci
Autor:
Jessica A, Davis, Zhanglin Lin, Cui, Madiha, Ghias, Xiaohong, Li, Robert, Goodloe, Chunxiao, Wang, Astra M, Liepa, Lisa M, Hess
Publikováno v:
J Gastrointest Oncol
BACKGROUND: Gastric or gastroesophageal junction (GEJ) adenocarcinoma is the most common form of gastric cancer diagnosed in the United States (US) each year. Diagnosis typically is in later stages of disease when it has advanced. Patients have been
Autor:
Alexandra S. Vitko, Pamela A. Martin, Sheng Zhang, Adam F. Johnston, Robert L. Ohsfeldt, Shen Zheng, Astra M. Liepa
Publikováno v:
Cancer Research. 83:P6-07
Background: Despite the good prognosis with treatment for most patients with hormone receptor positive (HR+), human epidermal growth factor receptor 2 negative (HER2-) early breast cancer (EBC), ~ 20–30% of patients experience locoregional or dista
Autor:
Holly Knoderer, Anindya Chatterjee, Paolo Abada, R. Wei, Samuel J. Klempner, Astra M. Liepa, Wasat Mansoor, Aafia Chaudhry, Eric Roeland
Publikováno v:
The Oncologist
Background Weight loss is common in advanced gastric and gastroesophageal junction adenocarcinoma (G/GEA); however, the prognostic implications of weight loss during the first cycle (C1) of chemotherapy remain poorly characterized. In this study, we
Autor:
Lucrezia Silvestro, Ferdinando De Vita, Arndt Vogel, Thomas Jens Ettrich, Eric Van Cutsem, Maria Di Bartolomeo, Yulia D'yachkova, Astra M. Liepa, Natalia Smolyakova, Mariusz Lukanowski, Yu-Jing Huang
Publikováno v:
Journal of Clinical Oncology. 41:341-341
341 Background: The objective was to describe the safety of ramucirumab (Ram) for previously treated advanced gastric cancer under real-world conditions in Europe and North America. Methods: This was a non-interventional, descriptive study of adult p
Autor:
Michael Grabner, Astra M. Liepa, Zhanglin Lin Cui, William R. Schelman, Liya Wang, Lisa M. Hess, Lee Bowman, Xiaohong Ivy Li
Publikováno v:
Pragmatic and Observational Research. 11:27-43
Background As real-world data resources expand and improve, there will increasingly be opportunities to study the effectiveness of interventions. There is a need to ensure that study designs explore potential sources of bias and either acknowledge or