Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Assumpcio Bosch"'
Autor:
Alexia Kagiava, Christos Karaiskos, George Lapathitis, Amanda Heslegrave, Irene Sargiannidou, Henrik Zetterberg, Assumpció Bosch, Kleopas A. Kleopa
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 30, Iss , Pp 377-393 (2023)
X-linked Charcot-Marie-Tooth disease type 1 (CMT1X) is a demyelinating neuropathy resulting from loss-of-function mutations affecting the GJB1/connexin 32 (Cx32) gene. We previously showed functional and morphological improvement in Gjb1-null mice fo
Externí odkaz:
https://doaj.org/article/d4f32062b79d47ecacc281e8ce18674a
Autor:
Joan Roig-Soriano, Cristina Sánchez-de-Diego, Jon Esandi-Jauregui, Sergi Verdés, Carmela R. Abraham, Assumpció Bosch, Francesc Ventura, Miguel Chillón
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract The aging-protective gene α-Klotho (KL) produces two main transcripts. The full-length mRNA generates a transmembrane protein that after proteolytic ectodomain shedding can be detected in serum as processed Klotho (p-KL), and a shorter tran
Externí odkaz:
https://doaj.org/article/6d0e213469a84004ae0d9ef85a56bf58
Autor:
Estel Gil, Assumpcio Bosch, David Lampe, Jose M Lizcano, Jose C Perales, Olivier Danos, Miguel Chillon
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e73227 (2013)
DNA transposons are mobile elements with the ability to mobilize and transport genetic information between different chromosomal loci. Unfortunately, most transposons copies are currently inactivated, little is known about mariner elements in humans
Externí odkaz:
https://doaj.org/article/89aa1b2975ed46929838190c38e31688
Autor:
Virginia Haurigot, Pilar Villacampa, Albert Ribera, Assumpcio Bosch, David Ramos, Jesus Ruberte, Fatima Bosch
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e41511 (2012)
Neovascularization associated with diabetic retinopathy (DR) and other ocular disorders is a leading cause of visual impairment and adult-onset blindness. Currently available treatments are merely palliative and offer temporary solutions. Here, we te
Externí odkaz:
https://doaj.org/article/e6c05e1f4d9d48f58b856f4efd74bff3
Publikováno v:
PLoS ONE, Vol 6, Iss 5, p e19564 (2011)
We have previously described a new family of mutant adenoviruses carrying different combinations of attB/attP sequences from bacteriophage PhiC31 flanking the Ad5 packaging domain. These novel helper viruses have a significantly delayed viral life cy
Externí odkaz:
https://doaj.org/article/face692722f548ef84b28f4191e0ef99
Autor:
Armando Almeida, Rita C. Assunção-Silva, Sandra Barata-Antunes, Assumpcio Bosch, Nicholas M. Boulis, Alice Braga, Bing Chen, Miguel Chillon, Jorge E. Collazos-Castro, João Cortinhas, Jianwu Dai, Ignacio Delgado-Martínez, Jaume del Valle, Madalena Esteves, Razan Faraj, Thais Federici, Michael G. Fehlings, Aline M. Fernandes, Miguel Gago, Guillermo García-Alías, Julian L. Gendreau, Eduardo D. Gomes, Alex Greven, Laureen D. Hachem, Regan Hamel, R.M. Ichiyama, Pavla Jendelová, Kristýna Kárová, Kristýna Kekulová, R.W.P. Kissane, Zuzana Kočí, Šárka Kubinová, Hugo Leite-Almeida, Mariah Lelos, Zhijia Liang, Rui Lima, Sara Monteiro Lopes, Alvaro Machado, Cláudia R. Marques, Susana Monteiro, Pedro M.D. Moreno, Xavier Navarro, Itse Onuwaje, Ana P. Pêgo, Inês M. Pereira, Luís Pereira de Almeida, Luca Peruzzotti-Jametti, James B. Phillips, Stefano Pluchino, Sofia Rocha, Nataliya Romanyuk, Carola Rutigliani, António J. Salgado, Nadine Correia Santos, Nuno A. Silva, Jayden A. Smith, Barbora Svobodová, Fábio G. Teixeira, Andreia Teixeira-Castro, Pavlos Texakalidis, Muhibullah S. Tora, Lucia Machova Urdzíková, Zhifeng Xiao, Bryan Yu, Yannan Zhao
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e33877bbd26bf36a71c983a078a4a0fa
https://doi.org/10.1016/b978-0-12-818084-6.00024-6
https://doi.org/10.1016/b978-0-12-818084-6.00024-6
Autor:
Assumpcio Bosch
Publikováno v:
Current Gene Therapy. 17
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::600e80dc1808082f695108ed35ab0d2d
https://doi.org/10.2174/156652321701170706174550
https://doi.org/10.2174/156652321701170706174550
Autor:
Marc Leal-Julià, Jorge J. Vilches, Andrea Onieva, Sergi Verdés, Ángela Sánchez, Miguel Chillón, Xavier Navarro, Assumpció Bosch
Publikováno v:
Molecular Metabolism, Vol 55, Iss , Pp 101408- (2022)
Objective: Peripheral neuropathy is the most common and debilitating complication of type 2 diabetes, leading to sensory loss, dysautonomia, hyperalgesia, and spontaneous noxious sensations. Despite the clinical and economic burden of diabetic neurop
Externí odkaz:
https://doaj.org/article/affdf19c56474612aa5aab5b0da3ff60
Autor:
Guillem Mòdol-Caballero, Mireia Herrando-Grabulosa, Sergi Verdés, Belén García-Lareu, Neus Hernández, Isaac Francos-Quijorna, Rubén López-Vales, Assumpció Bosch, Xavier Navarro
Publikováno v:
Frontiers in Neurology, Vol 12 (2021)
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease affecting the neuromuscular system for which currently there is no effective therapy. Motoneuron (MN) degeneration involves several complex mechanisms, including surrounding gli
Externí odkaz:
https://doaj.org/article/de3aa861366a46a9a56f3e37e6182c97
Autor:
Inmaculada Lopez-Font, Aitana Sogorb-Esteve, Míriam Javier-Torrent, Gunnar Brinkmalm, Mireia Herrando-Grabulosa, Belen García-Lareu, Janina Turon-Sans, Ricardo Rojas-García, Alberto Lleó, Carlos A. Saura, Henrik Zetterberg, Kaj Blennow, Assumpció Bosch, Xavier Navarro, Javier Sáez-Valero
Publikováno v:
Neurobiology of Disease, Vol 124, Iss , Pp 428-438 (2019)
ErbB4 is a transmembrane receptor tyrosine kinase that binds to neuregulins to activate signaling. Proteolytic cleavage of ErbB4 results in release of soluble fragments of ErbB4 into the interstitial fluid. Disruption of the neuregulin-ErbB4 pathway
Externí odkaz:
https://doaj.org/article/2deb1166980c4742a91bd862fb14d184