Aluminum chloride impairs learning and memory by P2X7 and A2A-receptor stimulations in hippocampus of mice

Autor: Heidrich G, Assmann Ce, Reichert Kp, Costa Pd, Silva ADd, Bottari Nb, Dressler, Lopes Tf, Schetinger Mrc, Morsch Vmm

Aluminum (Al) is considered a neurotoxic agent for biological systems and is recognized as a risk factor for neurodegenerative diseases. Al exposure occurs through the environment, water and human diet. The Al cationic form (Al3+) has been associated

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1e8622cb006764e17d2a68d92c8739b1
https://doi.org/10.21203/rs.3.rs-329182/v1

Effects of Free and Nanoencapsulated Benznidazole in Acute Trypanosoma cruzi Infection: Role of Cholinergic Pathway and Redox Status.

Autor: da Silva AD; Department of Biochemistry and Molecular Biology, Universidade Federal de Santa Maria, Santa Maria 97105-900, RS, Brazil., Fracasso M; Department of Biochemistry and Molecular Biology, Universidade Federal de Santa Maria, Santa Maria 97105-900, RS, Brazil., Bottari NB; Department of Microbiology and Parasitology, Universidade Federal de Pelotas, Pelotas 96015-560, Brazil., Palma TV; Department of Biochemistry and Molecular Biology, Universidade Federal de Santa Maria, Santa Maria 97105-900, RS, Brazil., Engelmann AM; Department of Biochemistry and Molecular Biology, Universidade Federal de Santa Maria, Santa Maria 97105-900, RS, Brazil., Castro MFV; Department of Biochemistry and Molecular Biology, Universidade Federal de Santa Maria, Santa Maria 97105-900, RS, Brazil., Assmann CE; Department of Biochemistry and Molecular Biology, Universidade Federal de Santa Maria, Santa Maria 97105-900, RS, Brazil., Mostardeiro V; Department of Biochemistry and Molecular Biology, Universidade Federal de Santa Maria, Santa Maria 97105-900, RS, Brazil., Reichert KP; Department of Biochemistry and Molecular Biology, Universidade Federal de Santa Maria, Santa Maria 97105-900, RS, Brazil., Nauderer J; Department of Biochemistry and Molecular Biology, Universidade Federal de Santa Maria, Santa Maria 97105-900, RS, Brazil., da Veiga ML; Department of Pathology, Universidade Federal de Santa Maria, Santa Maria 97105-900, RS, Brazil., da Rocha MIUM; Department of Pathology, Universidade Federal de Santa Maria, Santa Maria 97105-900, RS, Brazil., Milleti LC; Department of Animal Production, Universidade do Estado de Santa Catarina, Lages 88520-000, SC, Brazil., das Neves GB; Department of Animal Production, Universidade do Estado de Santa Catarina, Lages 88520-000, SC, Brazil., Gundel S; Center Science Heath, Universidade Franciscana, Santa Maria 97010-491, RS, Brazil., Ourique AF; Center Science Heath, Universidade Franciscana, Santa Maria 97010-491, RS, Brazil., Monteiro SG; Department of Microbiology and Parasitology, Universidade Federal de Santa Maria, Santa Maria 97105-900, RS, Brazil., Morsch VM; Department of Biochemistry and Molecular Biology, Universidade Federal de Santa Maria, Santa Maria 97105-900, RS, Brazil., Chitolina MR; Department of Biochemistry and Molecular Biology, Universidade Federal de Santa Maria, Santa Maria 97105-900, RS, Brazil., Da Silva AS; Department of Animal Science, Universidade do Estado de Santa Catarina, Chapecó 89815-630, SC, Brazil.

Publikováno v: Pharmaceuticals (Basel, Switzerland) [Pharmaceuticals (Basel)] 2024 Oct 19; Vol. 17 (10). Date of Electronic Publication: 2024 Oct 19.

Waterborne atenolol disrupts neurobehavioral and neurochemical responses in adult zebrafish.

Autor: Adedara IA; Department of Food Technology and Science, Center of Rural Sciences, Federal University of Santa Maria, Camobi, Santa Maria, RS, 97105-900, Brazil. isaac.adedara@ufsm.br.; Drug Metabolism and Toxicology Research Laboratories, Department of Biochemistry, College of Medicine, University of Ibadan, Ibadan, Nigeria. isaac.adedara@ufsm.br.; Laboratory of Experimental Neuropsychobiology, Department of Biochemistry and Molecular Biology, Natural and Exact Sciences Center, Federal University of Santa Maria, Camobi, 1000 Roraima Avenue, Santa Maria, RS, 97105-900, Brazil. isaac.adedara@ufsm.br., Gonçalves FL; Laboratory of Experimental Neuropsychobiology, Department of Biochemistry and Molecular Biology, Natural and Exact Sciences Center, Federal University of Santa Maria, Camobi, 1000 Roraima Avenue, Santa Maria, RS, 97105-900, Brazil.; Graduate Program in Biological Sciences: Toxicological Biochemistry, Federal University of Santa Maria, Camobi, 1000 Roraima Avenue, Santa Maria, RS, 97105-900, Brazil., Mohammed KA; Laboratory of Experimental Neuropsychobiology, Department of Biochemistry and Molecular Biology, Natural and Exact Sciences Center, Federal University of Santa Maria, Camobi, 1000 Roraima Avenue, Santa Maria, RS, 97105-900, Brazil.; Graduate Program in Biological Sciences: Toxicological Biochemistry, Federal University of Santa Maria, Camobi, 1000 Roraima Avenue, Santa Maria, RS, 97105-900, Brazil., Borba JV; Laboratory of Experimental Neuropsychobiology, Department of Biochemistry and Molecular Biology, Natural and Exact Sciences Center, Federal University of Santa Maria, Camobi, 1000 Roraima Avenue, Santa Maria, RS, 97105-900, Brazil.; Graduate Program in Biological Sciences: Toxicological Biochemistry, Federal University of Santa Maria, Camobi, 1000 Roraima Avenue, Santa Maria, RS, 97105-900, Brazil., Canzian J; Laboratory of Experimental Neuropsychobiology, Department of Biochemistry and Molecular Biology, Natural and Exact Sciences Center, Federal University of Santa Maria, Camobi, 1000 Roraima Avenue, Santa Maria, RS, 97105-900, Brazil.; Graduate Program in Biological Sciences: Toxicological Biochemistry, Federal University of Santa Maria, Camobi, 1000 Roraima Avenue, Santa Maria, RS, 97105-900, Brazil., Resmim CM; Laboratory of Experimental Neuropsychobiology, Department of Biochemistry and Molecular Biology, Natural and Exact Sciences Center, Federal University of Santa Maria, Camobi, 1000 Roraima Avenue, Santa Maria, RS, 97105-900, Brazil.; Graduate Program in Biological Sciences: Toxicological Biochemistry, Federal University of Santa Maria, Camobi, 1000 Roraima Avenue, Santa Maria, RS, 97105-900, Brazil., Claro MT; Graduate Program in Biological Sciences: Toxicological Biochemistry, Federal University of Santa Maria, Camobi, 1000 Roraima Avenue, Santa Maria, RS, 97105-900, Brazil., Macedo GT; Graduate Program in Biological Sciences: Toxicological Biochemistry, Federal University of Santa Maria, Camobi, 1000 Roraima Avenue, Santa Maria, RS, 97105-900, Brazil., Mostardeiro VB; Graduate Program in Biological Sciences: Toxicological Biochemistry, Federal University of Santa Maria, Camobi, 1000 Roraima Avenue, Santa Maria, RS, 97105-900, Brazil., Assmann CE; Graduate Program in Biological Sciences: Toxicological Biochemistry, Federal University of Santa Maria, Camobi, 1000 Roraima Avenue, Santa Maria, RS, 97105-900, Brazil., Monteiro CS; Department of Food Technology and Science, Center of Rural Sciences, Federal University of Santa Maria, Camobi, Santa Maria, RS, 97105-900, Brazil., Emanuelli T; Department of Food Technology and Science, Center of Rural Sciences, Federal University of Santa Maria, Camobi, Santa Maria, RS, 97105-900, Brazil., Schetinger MRC; Graduate Program in Biological Sciences: Toxicological Biochemistry, Federal University of Santa Maria, Camobi, 1000 Roraima Avenue, Santa Maria, RS, 97105-900, Brazil., Barbosa NV; Graduate Program in Biological Sciences: Toxicological Biochemistry, Federal University of Santa Maria, Camobi, 1000 Roraima Avenue, Santa Maria, RS, 97105-900, Brazil., Rosemberg DB; Laboratory of Experimental Neuropsychobiology, Department of Biochemistry and Molecular Biology, Natural and Exact Sciences Center, Federal University of Santa Maria, Camobi, 1000 Roraima Avenue, Santa Maria, RS, 97105-900, Brazil.; Graduate Program in Biological Sciences: Toxicological Biochemistry, Federal University of Santa Maria, Camobi, 1000 Roraima Avenue, Santa Maria, RS, 97105-900, Brazil.; The International Zebrafish Neuroscience Research Consortium (ZNRC), 309 Palmer Court, Slidell, LA, 70458, USA.

Publikováno v: Environmental science and pollution research international [Environ Sci Pollut Res Int] 2024 Aug; Vol. 31 (36), pp. 49200-49213. Date of Electronic Publication: 2024 Jul 25.

Purinergic signaling influences the neuroinflammatory outcomes of a testosterone-derived synthetic in female rats: Resistance training protective effects on brain health.

Autor: Pereira ADS; Graduate Program in Toxicological Biochemistry, Department of Biochemistry and Molecular Biology, Federal University of Santa Maria (UFSM), Santa Maria, RS, Brazil. Electronic address: aline.s_pereira@hotmail.com., Bottari NB; Graduate Program in Toxicological Biochemistry, Department of Biochemistry and Molecular Biology, Federal University of Santa Maria (UFSM), Santa Maria, RS, Brazil., Nauderer JN; Graduate Program in Toxicological Biochemistry, Department of Biochemistry and Molecular Biology, Federal University of Santa Maria (UFSM), Santa Maria, RS, Brazil., Assmann CE; Graduate Program in Toxicological Biochemistry, Department of Biochemistry and Molecular Biology, Federal University of Santa Maria (UFSM), Santa Maria, RS, Brazil., Copetti PM; Graduate Program in Toxicological Biochemistry, Department of Biochemistry and Molecular Biology, Federal University of Santa Maria (UFSM), Santa Maria, RS, Brazil., Reichert KP; Graduate Program in Toxicological Biochemistry, Department of Biochemistry and Molecular Biology, Federal University of Santa Maria (UFSM), Santa Maria, RS, Brazil., Mostardeiro VB; Graduate Program in Toxicological Biochemistry, Department of Biochemistry and Molecular Biology, Federal University of Santa Maria (UFSM), Santa Maria, RS, Brazil., da Silveira MV; Graduate Program in Toxicological Biochemistry, Department of Biochemistry and Molecular Biology, Federal University of Santa Maria (UFSM), Santa Maria, RS, Brazil., Morsch VMM; Graduate Program in Toxicological Biochemistry, Department of Biochemistry and Molecular Biology, Federal University of Santa Maria (UFSM), Santa Maria, RS, Brazil., Schetinger MRC; Graduate Program in Toxicological Biochemistry, Department of Biochemistry and Molecular Biology, Federal University of Santa Maria (UFSM), Santa Maria, RS, Brazil. Electronic address: mariachitolina@gmail.com.

Publikováno v: Steroids [Steroids] 2024 Mar; Vol. 203, pp. 109352. Date of Electronic Publication: 2023 Dec 20.

Trypanosoma cruzi: Does the intake of nanoencapsulated benznidazole control acute infections?

Autor: Dutra da Silva A; Programa de Pós-Graduação em Bioquímica Toxicológica, Universidade Federal de Santa Maria, Santa Maria, Rio Grande do Sul, Brazil. Electronic address: anielen.dutra@gmail.com., Fracasso M; Programa de Pós-Graduação em Bioquímica Toxicológica, Universidade Federal de Santa Maria, Santa Maria, Rio Grande do Sul, Brazil., Bottari NB; Programa de Pós-Graduação em Bioquímica Toxicológica, Universidade Federal de Santa Maria, Santa Maria, Rio Grande do Sul, Brazil., Gundel S; Ciências das Saúde, Universidade Franciscana, Santa Maria, Rio Grande do Sul, Brazil., Ourique AF; Ciências das Saúde, Universidade Franciscana, Santa Maria, Rio Grande do Sul, Brazil., Assmann CE; Programa de Pós-Graduação em Bioquímica Toxicológica, Universidade Federal de Santa Maria, Santa Maria, Rio Grande do Sul, Brazil., Ferreira DASP; Programa de Pós-Graduação em Bioquímica Toxicológica, Universidade Federal de Santa Maria, Santa Maria, Rio Grande do Sul, Brazil., Castro MFV; Programa de Pós-Graduação em Bioquímica Toxicológica, Universidade Federal de Santa Maria, Santa Maria, Rio Grande do Sul, Brazil., Reichert KP; Programa de Pós-Graduação em Bioquímica Toxicológica, Universidade Federal de Santa Maria, Santa Maria, Rio Grande do Sul, Brazil., de Souza LAF; Universidade Federal do Paraná, Curitiba, Paraná, Brazil., da Veiga ML; Departamento de Morfologia, Universidade Federal de Santa Maria, Santa Maria, Rio Grande do Sul, Brazil., da Rocha MIUM; Departamento de Morfologia, Universidade Federal de Santa Maria, Santa Maria, Rio Grande do Sul, Brazil., Monteiro SG; Departamento de Microbiologia e Parasitologia, Universidade Federal de Santa Maria, Santa Maria, Rio Grande do Sul, Brazil., Morsch VM; Programa de Pós-Graduação em Bioquímica Toxicológica, Universidade Federal de Santa Maria, Santa Maria, Rio Grande do Sul, Brazil., Chitolina Schetinger MR; Programa de Pós-Graduação em Bioquímica Toxicológica, Universidade Federal de Santa Maria, Santa Maria, Rio Grande do Sul, Brazil., da Silva AS; Programa de Pós-Graduação em Bioquímica Toxicológica, Universidade Federal de Santa Maria, Santa Maria, Rio Grande do Sul, Brazil; Departamento de Zootecnia, Universidade do Estado de Santa Catarina, Chapecó, Santa Catarina, Brazil. Electronic address: aleksandro_ss@yahoo.com.br.

Publikováno v: Experimental parasitology [Exp Parasitol] 2023 Jun; Vol. 249, pp. 108520. Date of Electronic Publication: 2023 Mar 29.