Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Assmaa ElSheikh"'
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract ATP-sensitive potassium (KATP) channels, composed of four pore-lining Kir6.2 subunits and four regulatory sulfonylurea receptor 1 (SUR1) subunits, control insulin secretion in pancreatic β-cells. KATP channel opening is stimulated by PIP2 a
Externí odkaz:
https://doaj.org/article/51943945f40e4fbd84e1af7be3d9f24b
Publikováno v:
Channels, Vol 18, Iss 1 (2024)
ABSTRACTKATP channels are ligand-gated potassium channels that couple cellular energetics with membrane potential to regulate cell activity. Each channel is an eight subunit complex comprising four central pore-forming Kir6 inward rectifier potassium
Externí odkaz:
https://doaj.org/article/ae5b90c7be9645178e9ac3531c0fa733
Autor:
Assmaa ElSheikh, Show-Ling Shyng
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
Congenital hyperinsulinism (CHI) is the most common cause of persistent hypoglycemia in infancy/childhood and is a serious condition associated with severe recurrent attacks of hypoglycemia due to dysregulated insulin secretion. Timely diagnosis and
Externí odkaz:
https://doaj.org/article/bcfafffee5fa466bad972e67f318d309
Autor:
Hua-Qian Yang, Fabio A. Echeverry, Assmaa ElSheikh, Ivan Gando, Sophia Anez Arredondo, Natalie Samper, Timothy Cardozo, Mario Delmar, Show-Ling Shyng, William A. Coetzee
Publikováno v:
Am J Physiol Cell Physiol
Sarcolemmal/plasmalemmal ATP-sensitive K+ (KATP) channels have key roles in many cell types and tissues. Hundreds of studies have described how the KATP channel activity and ATP sensitivity can be regulated by changes in the cellular metabolic state,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::011749ed2fbef18c0573653ae17c6815
https://europepmc.org/articles/PMC9169827/
https://europepmc.org/articles/PMC9169827/
Autor:
Jeremy Dunford, Assmaa ElSheikh, Yi Wu, Zhongying Yang, Show Ling Shyng, Dale A. Fortin, Paul Kievit, Veronica A. Cochrane
Publikováno v:
J Biol Chem
The adipocyte-derived hormone leptin increases trafficking of K(ATP) and Kv2.1 channels to the pancreatic β-cell surface, resulting in membrane hyperpolarization and suppression of insulin secretion. We have previously shown that this effect of lept
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f97fe8e1d16ae8627e3af12a0557c952
https://pubmed.ncbi.nlm.nih.gov/33037073
https://pubmed.ncbi.nlm.nih.gov/33037073
Autor:
Wallach, Izhar1 (AUTHOR), Bernard, Denzil1 (AUTHOR), Nguyen, Kong1 (AUTHOR), Ho, Gregory1 (AUTHOR), Morrison, Adrian1 (AUTHOR), Stecula, Adrian1 (AUTHOR), Rosnik, Andreana1 (AUTHOR), O'Sullivan, Ann Marie1 (AUTHOR), Davtyan, Aram1 (AUTHOR), Samudio, Ben1 (AUTHOR), Thomas, Bill1 (AUTHOR), Worley, Brad1 (AUTHOR), Butler, Brittany1 (AUTHOR), Laggner, Christian1 (AUTHOR), Thayer, Desiree1 (AUTHOR), Moharreri, Ehsan1 (AUTHOR), Friedland, Greg1 (AUTHOR), Truong, Ha1 (AUTHOR), van den Bedem, Henry1 (AUTHOR), Ng, Ho Leung1 (AUTHOR)
Publikováno v:
Scientific Reports. 9/16/2024, Vol. 14 Issue 1, p1-2. 2p.
Autor:
Cheng-Ting Lee, Wen-Hao Tsai, Chien-Ching Chang, Pei-Chun Chen, Cathy Shen-Jang Fann, Hsueh-Kai Chang, Shih-Yao Liu, Mu-Zon Wu, Pao-Chin Chiu, Wen-Ming Hsu, Wei-Shiung Yang, Ling-Ping Lai, Wen-Yu Tsai, Shi-Bing Yang, Pei-Lung Chen
Publikováno v:
Frontiers in Endocrinology; 2023, p1-12, 12p
Autor:
ElSheikh, Assmaa, Show-Ling Shyng
Publikováno v:
Frontiers in Endocrinology; 3/28/2023, Vol. 14, p1-12, 12p
Autor:
Hua-Qian Yang, Echeverry, Fabio A., ElSheikh, Assmaa, Gando, Ivan, Arredondo, Sophia Anez, Samper, Natalie, Cardozo, Timothy, Delmar, Mario, Show-Ling Shyng, Coetzee, William A.
Publikováno v:
American Journal of Physiology: Cell Physiology; Jun2022, Vol. 322 Issue 6, pC1230-C1247, 18p