Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Assiatu Crossman"'
Autor:
Praveen Prakhar, Jaylene Alvarez-DelValle, Hilary Keller, Assiatu Crossman, Xuguang Tai, Yoo Kyoung Park, Jung-Hyun Park
Publikováno v:
JCI Insight, Vol 6, Iss 21 (2021)
Foxp3+ Tregs are potent immunosuppressive CD4+ T cells that are critical to maintain immune quiescence and prevent autoimmunity. Both the generation and maintenance of Foxp3+ Tregs depend on the cytokine IL-2. Hence, the expression of the IL-2 recept
Externí odkaz:
https://doaj.org/article/39d57058e50c4456b7e8dac266f6cb2d
CD138 expression is a molecular signature but not a developmental requirement for RORγt+ NKT17 cells
Publikováno v:
JCI Insight, Vol 6, Iss 18 (2021)
Invariant NKT (iNKT) cells are potent immunomodulatory cells that acquire effector function during their development in the thymus. IL-17–producing iNKT cells are commonly referred to as NKT17 cells, and they are unique among iNKT cells to express
Externí odkaz:
https://doaj.org/article/9b2aac04b82f466aa66b9a6715a68b16
Autor:
Hee Yeun Won, Hye Kyung Kim, Assiatu Crossman, Parirokh Awasthi, Ronald E. Gress, Jung-Hyun Park
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Invariant NKT (iNKT) cells are thymus-generated innate-like T cells, comprised of three distinct subsets with divergent effector functions. The molecular mechanism that drives the lineage trifurcation of immature iNKT cells into the NKT1, NKT2, and N
Externí odkaz:
https://doaj.org/article/a6a1f114551b40de9ad8b15c0a680468
Autor:
Xuguang Tai, Alyssa Indart, Mirelle Rojano, Jie Guo, Nicolai Apenes, Tejas Kadakia, Marco Craveiro, Amala Alag, Ruth Etzensperger, Mohamed Elsherif Badr, Flora Zhang, Zhongmei Zhang, Jie Mu, Terry Guinter, Assiatu Crossman, Larry Granger, Susan Sharrow, Xuyu Zhou, Alfred Singer
Publikováno v:
Nature Immunology. 24:637-651
Thymocytes bearing autoreactive T cell receptors (TCRs) are agonist-signaled by TCR/co-stimulatory molecules to either undergo clonal deletion or to differentiate into specialized regulatory T (Treg) or effector T (Teff) CD4+ cells. How these differe
Autor:
Can Li, Hye Kyung Kim, Praveen Prakhar, Shunqun Luo, Assiatu Crossman, Davinna L. Ligons, Megan A. Luckey, Parirokh Awasthi, Ronald E. Gress, Jung-Hyun Park
Publikováno v:
Mucosal Immunology. 15:882-895
Autor:
Shunqun Luo, Nurcin Liman, Can Li, Assiatu Crossman, Eddie C. Y. Wang, Françoise Meylan, Jung-Hyun Park
Publikováno v:
Cellular and Molecular Life Sciences. 80
Autor:
Assiatu Crossman, Vanja Lazarevic, Su Jin Hwang, Can Li, Davinna L. Ligons, Jung-Hyun Park, Praveen Prakhar, Nurcin Liman, Hilary R. Keller, Yoo Kyoung Park, Megan A. Luckey
Publikováno v:
Cell Mol Life Sci
Integrin CD103 mediates the adhesion and tissue retention of T cells by binding to E-cadherin which is abundant on epithelial cells. Notably, CD103 is highly expressed on CD8 T cells but conspicuously absent on most CD4 T cells. The mechanism control
Autor:
Can, Li, Hye Kyung, Kim, Praveen, Prakhar, Shunqun, Luo, Assiatu, Crossman, Davinna L, Ligons, Megan A, Luckey, Parirokh, Awasthi, Ronald E, Gress, Jung-Hyun, Park
Publikováno v:
Mucosal immunology. 15(5)
The chemokine receptor CCR9 equips T cells with the ability to respond to CCL25, a chemokine that is highly expressed in the thymus and the small intestine (SI). Notably, CCR9 is mostly expressed on CD8 but not on CD4 lineage T cells, thus imposing d
Autor:
Jaylene Alvarez-DelValle, Hilary R. Keller, Xuguang Tai, Assiatu Crossman, Praveen Prakhar, Yoo Kyoung Park, Jung-Hyun Park
Publikováno v:
JCI Insight
Foxp3+ Tregs are potent immunosuppressive CD4+ T cells that are critical to maintain immune quiescence and prevent autoimmunity. Both the generation and maintenance of Foxp3+ Tregs depend on the cytokine IL-2. Hence, the expression of the IL-2 recept
Invariant natural killer T (iNKT) cells are thymus-generated T cells with innate-like characteristics and effector function. Several functionally distinct iNKT subsets have been identified, but NKT17 is the only iNKT subset that produces the proinfla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ffdc3133c5d704e23fe8c63615334e67
https://doi.org/10.1101/2021.09.27.461992
https://doi.org/10.1101/2021.09.27.461992