Zobrazeno 1 - 10
of 230
pro vyhledávání: '"Assay systems"'
Autor:
David Fleischer, Vasant Chellappa, Olivia Alley, Adi Gilboa-Geffen, Sarah Stidham, Wayne G. Shreffler, Hugh A. Sampson, Jonathan M. Spergel, Lucas Yoder, Valerie Villareal
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Scientific Reports
Scientific Reports
Aptamers, due to their small size, strong target affinity, and ease of chemical modification, are ideally suited for molecular detection technologies. Here, we describe successful use of aptamer technology in a consumer device for the detection of pe
Autor:
Jiandong Yang, Yoshikazu Hirai, Kei Iida, Shinji Ito, Marika Trumm, Shiho Terada, Risako Sakai, Toshiyuki Tsuchiya, Osamu Tabata, Ken-ichiro Kamei
Publikováno v:
Communications Biology. 6
Non-alcoholic fatty liver disease (NAFLD) afflicts a significant percentage of the population; however, no effective treatments have yet been established because of the unsuitability of in vitro assays and animal experimental models. Here, we present
Autor:
Atiya Mansoor, Stefano Cairo, Sandra Rugonyi, Charles Keller, Noah E. Berlow, Samuel Rasmussen, Lisa Hudson Price
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-8 (2021)
Scientific Reports
Scientific Reports
Preclinical cancer research ranges from in vitro studies that are inexpensive and not necessarily reflective of the tumor microenvironment to mouse studies that are better models but prohibitively expensive at scale. Chorioallantoic membrane (CAM) as
Autor:
Daniel Fraiman, Hugo G Menzella, José M. Martínez, Silvina Ponce Dawson, Pablo A. Ferrari, Inés Armendáriz
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Scientific Reports
Scientific Reports
The progress of the SARS-CoV-2 pandemic requires the design of large-scale, cost-effective testing programs. Pooling samples provides a solution if the tests are sensitive enough. In this regard, the use of the gold standard, RT-qPCR, raises some con
Autor:
Yu-Jui Chiu, Eugene Tu, Sadik C. Esener, Ajay Sapre, Kyle T. Gustafson, Jesus Bueno Alvarez, Brett S. Walker, Melissa H. Wong, Jared M. Fischer, Jose L. Montoya Mira
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-9 (2021)
Communications Biology
Communications Biology
Cellular circulating biomarkers from the primary tumor such as circulating tumor cells (CTCs) and circulating hybrid cells (CHCs) have been described to harbor tumor-like phenotype and genotype. CHCs are present in higher numbers than CTCs supporting
Autor:
Yuhei Tanaka, Kenji Shimoda, Kazufumi Sakamoto, Yoshitsune Hondo, Mitsuru Sentoku, Rikuto Sekine, Kenji Yasuda, Takahito Kikuchi, Haruki Watanabe
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Scientific Reports
Scientific Reports
Conventional neuronal network pattern formation techniques cannot control the arrangement of axons and dendrites because network structures must be fixed before neurite differentiation. To overcome this limitation, we developed a non-destructive step
Autor:
Tahmineh Jalali, Mohammad Hassan Pouriayevali, Mostafa Salehi-Vaziri, Seyed Latif Mousavi Gargari
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Scientific Reports
Scientific Reports
Crimean-Congo hemorrhagic fever (CCHF) is an acute viral zoonotic disease. The widespread geographic distribution of the disease and the increase in the incidence of the disease from new regions, placed CCHF in a list of public health emergency conte
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-9 (2021)
Nature Communications
Nature Communications
The need for rapid, accurate, and scalable testing systems for COVID-19 diagnosis is clear and urgent. Here, we report a rapid Scalable and Portable Testing (SPOT) system consisting of a rapid, highly sensitive, and accurate assay and a battery-power
Autor:
Lukas Bokelmann, Stephan Riesenberg, Svante Pääbo, Stephan Borte, Tomislav Maricic, Matthias Meyer, Olaf Nickel
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-8 (2021)
Nature Communications
Nature Communications
Efforts to contain the spread of SARS-CoV-2 have spurred the need for reliable, rapid, and cost-effective diagnostic methods which can be applied to large numbers of people. However, current standard protocols for the detection of viral nucleic acids
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
Nature Communications
Nature Communications
Much effort has been expended on building cellular computational devices for different applications. Despite the significant advances, there are still several addressable restraints to achieve the necessary technological transference. These improveme