Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Assaf Ezra"'
Autor:
Riccardo Rampado, Gonna Somu Naidu, Olga Karpov, Meir Goldsmith, Preeti Sharma, Assaf Ezra, Lior Stotsky, Dor Breier, Dan Peer
Publikováno v:
Advanced Science, Vol 12, Iss 3, Pp n/a-n/a (2025)
Abstract Lipid Nanoparticles (LNPs) recently emerged as an invaluable RNA delivery platform. With many LNP‐based therapeutics in the pre‐clinical and clinical pipelines, there is extensive research dedicated to improving LNPs. These efforts focus
Externí odkaz:
https://doaj.org/article/f968c49a919b47b189577ee709728981
Autor:
Gonna Somu Naidu, Seok‐Beom Yong, Srinivas Ramishetti, Riccardo Rampado, Preeti Sharma, Assaf Ezra, Meir Goldsmith, Inbal Hazan‐Halevy, Sushmita Chatterjee, Anjaiah Aitha, Dan Peer
Publikováno v:
Advanced Science, Vol 10, Iss 19, Pp n/a-n/a (2023)
Abstract Ionizable lipid‐based nanoparticles (LNPs) are the most advanced non‐viral drug delivery systems for RNA therapeutics and vaccines. However, cell type‐specific, extrahepatic mRNA delivery is still a major hurdle, hampering the developm
Externí odkaz:
https://doaj.org/article/8f0b4086caf74fd7a771aab230a4d877
Autor:
Polina Rabinovich-Toidman, Inna Rabinovich-Nikitin, Assaf Ezra, Beka Barbiro, Hilla Fogel, Inna Slutsky, Beka Solomon
Publikováno v:
PLoS ONE, Vol 10, Iss 11, p e0143420 (2015)
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease and it is the most common adult onset neurodegenerative disorder affecting motor neurons. There is currently no effective treatment for ALS and our understanding of the patholog
Externí odkaz:
https://doaj.org/article/9ba59100d7f749ccb8bde0b5b544fa61
Autor:
Sushmita Chatterjee, Gonna Somu Naidu, Inbal Hazan-Halevy, Hanna Grobe, Assaf Ezra, Preeti Sharma, Meir Goldsmith, Srinivas Ramishetti, David Sprinzak, Ronen Zaidel-Bar, Dan Peer
Publikováno v:
Science Advances. 9
The potential of microtubule-associated protein targets for cancer therapeutics remains largely unexplored due to the lack of target-specific agents. Here, we explored the therapeutic potential of targeting cytoskeleton-associated protein 5 (CKAP5),
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d69bf0cc7299dd16cf48da0dd90387f4
https://doi.org/10.1126/sciadv.ade4800
https://doi.org/10.1126/sciadv.ade4800
Autor:
Edo Kon, Yinon Levy, Uri Elia, Hila Cohen, Inbal Hazan-Halevy, Moshe Aftalion, Assaf Ezra, Erez Bar-Haim, Gonna Somu Naidu, Yael Diesendruck, Shahar Rotem, Nitay Ad-El, Meir Goldsmith, Emanuelle Mamroud, Dan Peer, Ofer Cohen
Publikováno v:
Science Advances. 9
Messenger RNA (mRNA) lipid nanoparticle (LNP) vaccines have emerged as an effective vaccination strategy. Although currently applied toward viral pathogens, data concerning the platform’s effectiveness against bacterial pathogens are limited. Here,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3f9e9397ac423e9f1c7aafe6f2703076
https://doi.org/10.1126/sciadv.adg1036
https://doi.org/10.1126/sciadv.adg1036
Autor:
Edo Kon, Yinon Levy, Uri Elia, Hila Cohen, Inbal Hazan-Halevy, Moshe Aftalion, Assaf Ezra, Erez Bar-Haim, Gonna Somu Naidu, Yael Diesendruck, Shahar Rotem, Nitay Ad-El, Meir Goldsmith, Emanuelle Mamroud, Dan Peer, Ofer Cohen
Plague is a rapidly deteriorating contagious disease that has killed millions of people during the history of mankind and is caused by the gram-negative bacterium Yersinia pestis. Currently, the disease is treated effectively with antibiotics. Howeve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e7ce8b8b9ce6b96dd9c809e7a47a5f6b
https://doi.org/10.1101/2022.08.07.503096
https://doi.org/10.1101/2022.08.07.503096
Autor:
Sushmita Chatterjee, Gonna Somu Naidu, Inbal Hazan-Halevy, Hanna Grobe, Assaf Ezra, Srinivas Ramishetti, David Sprinzak, Ronen Zaidel-Bar, Dan Peer
Cell mitosis is an attractive target for cancer therapy. Presently, anti-mitotic drugs are limited to tubulin binding agents and kinase inhibitors. While there is a long list of potential microtubule associated protein targets that play an important
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1033950c8050972a2f22b41baf1070f4
https://doi.org/10.21203/rs.3.rs-1898494/v1
https://doi.org/10.21203/rs.3.rs-1898494/v1
Autor:
Xizhou Liu, Tuomas P. J. Knowles, Lee Schnaider, Ehud Gazit, Zenon Toprakcioglu, Assaf Ezra, Darya Bychenko, Aviad Levin
Publikováno v:
Nano Letters. 20:1590-1597
Self-assembling peptides and proteins have the potential to serve as multifunctional building blocks for the generation of versatile materials for a wide range of biomedical applications. In particular, supramolecular hydrogels comprised of self-asse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::199eb58fa9582b72e606befa14963383
https://doi.org/10.1021/acs.nanolett.9b04290
https://doi.org/10.1021/acs.nanolett.9b04290
Autor:
Seok‐Beom Yong, Srinivas Ramishetti, Meir Goldsmith, Yael Diesendruck, Inbal Hazan‐Halevy, Sushmita Chatterjee, Gonna Somu Naidu, Assaf Ezra, Dan Peer
Publikováno v:
Advanced materials (Deerfield Beach, Fla.). 34(13)
Chemo-immunotherapy is a combination of "standard-of-care" chemotherapy with immunotherapy and it is considered the most advanced therapeutic modality for various types of cancers. However, many cancer patients still poorly respond to current regimen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88a4ebc9f02617de53fc7deaf47d4605
https://pubmed.ncbi.nlm.nih.gov/35044699
https://pubmed.ncbi.nlm.nih.gov/35044699
Publikováno v:
Journal of Alzheimer's disease : JAD. 78(2)
Background: Alzheimer’s disease (AD), the prevalent dementia in the elderly, involves many related and interdependent pathologies that manifest simultaneously, leading to cognitive impairment and death. Amyloid-β (Aβ) accumulation in the brain tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fcdfd53f5557fae2e47fcf21744393e
https://pubmed.ncbi.nlm.nih.gov/33016905
https://pubmed.ncbi.nlm.nih.gov/33016905