Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Assaad Semaan"'
Autor:
Sanjeev Kumar, Sudeshna Bandyopadhyay, Assaad Semaan, Jay P Shah, Haider Mahdi, Robert Morris, Adnan Munkarah, Rouba Ali-Fehmi
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e21912 (2011)
BACKGROUND: The role of frozen section (FS) in intraoperative decision making for surgical staging of endometrial cancer is controversial. Objective of this study is to assess the agreement rate between the FS and paraffin section (PS); and the poten
Externí odkaz:
https://doaj.org/article/fc478078b65d432b9052467437ef02f0
Publikováno v:
Pharmacogenetics and genomics. 27(7)
Background Alterations in nuclear pore complex (NPC) genes have been previously associated with response to chemotherapy. Using agnostic exome sequencing, we envisioned that new alleles in NPC genes, predictive of sensitivity to platinum treatment, c
Autor:
Shelly Seward, Sreedhar Chamala, David L. Bouwman, Assaad Semaan, Donald W. Weaver, Aamer Qazi, Ramesh B. Batchu, Scott A. Gruber, Oksana V. Gruzdyn, Vasu B. Dhulipala
Publikováno v:
Surgery. 154:739-747
Purpose Enhancer of zeste homologue 2 (EZH2), a component of the chromatin modification protein complex, is upregulated in pancreatic ductal adenocarcinoma (PDAC), whereas loss of p53 and its downstream target, p21 waf1/cip1 , is also observed freque
Autor:
Donald W. Weaver, Seema Sethi, David L. Bouwman, Robert T. Morris, Shelly Seward, Aamer Qazi, Assaad Semaan, Sreedhar Chamala, Ramesh B. Batchu, Scott A. Gruber, David Cameron, Rouba Ali-Fehmi, Oksana V. Gruzdyn, Adnan R. Munkarah, Sanjeev Kumar, Christopher C. Bryant
Publikováno v:
Cancer Letters. 336:53-60
The enhancer of zeste homolog 2 (EZH2) methyltransferase is a transcriptional repressor. EZH2 is abnormally elevated in epithelial ovarian cancer (EOC). We demonstrated that EZH2 knockdown inhibited cell growth, activated apoptosis, and enhanced chem
Publikováno v:
International Journal of Gynecological Cancer. 23:1118-1126
We aimed to compare the differences in demographic features, clinicopathologic features, and survival in patients with vulvar/vaginal melanoma versus cutaneous melanoma with a special emphasis on race.Data were obtained from the Surveillance Epidemio
Autor:
Robert T. Morris, Daniel Schultz, Yaser R. Hussein, Marisa R. Nucci, Baraa Alosh, Ira Winer, Esther Oliva, Rouba Ali-Fehmi, Faisal Quershi, Adnan R. Munkarah, Sudeshna Bandyopadhyay, Koen Van de Vijver, Farah Tabassum, Haider Mahdi, Kinda Hayek, Assaad Semaan, Michele L. Cote, Ismail Mert
Publikováno v:
International Journal of Gynecological Pathology, 32(2), 181-187. LIPPINCOTT WILLIAMS & WILKINS
The objective of this study was to analyze the clinical and pathologic factors in patients with uterine serous carcinoma confined to the endometrium. A total of 236 uterine serous carcinoma patients from the pathology databases of 4 large academic in
Autor:
Baraa Alosh, Adnan R. Munkarah, Assaad Semaan, Anil K. Sood, Rouba Ali-Fehmi, Kinda Hayek, Jun Zhou, Zhengming Chen, Tarek Jazaerly, Yaser R. Hussein, Ju Won Roh, Sudeshna Bandyopadhyay
Publikováno v:
Gynecologic Oncology. 128:344-348
The deregulation of E-cadherin is associated with Src/FAK signaling axis and histone deacetylase (HDAC)/EZH2 activity. However, the association between EZH2 and FAK and its clinical significance in endometrial carcinoma has not been reported.202 arch
Autor:
Fadi W. Abdul-Karim, Kinda Hayek, Richard Morris, Baraa Alosh, Adnan R. Munkarah, D. Schulz, Assaad Semaan, Haider Mahdi, Michele L. Cote, Faisal Qureshi, Esther Oliva, Marisa R. Nucci, K. K. Van de Vijver, Sudeshna Bandyopadhyay, Rouba Ali-Fehmi, Ira Winer, Yaser R. Hussein
Publikováno v:
Gynecologic Oncology, 128(2), 316-321. Elsevier Science
Uterine serous carcinoma (USC) constitutes 10% of uterine cancers but ~40% of deaths. Tumor size is a known prognostic factor in other solid tumors. In endometriod cancers it is one element used to identify the need for complete staging, while its si
Autor:
Z. Al-Wahab, Robert T. Morris, Shelly Seward, Michele L. Cote, Adnan R. Munkarah, Rouba Ali-Fehmi, Sudeshna Bandyopadhyay, Mohamed A. Elshaikh, Assaad Semaan
Publikováno v:
International Journal of Gynecologic Cancer. 22:452-456
ObjectiveOur aim was to evaluate the prognostic significance of the revised 2009 International Federation of Gynecology and Obstetrics (FIGO) staging criteria in patients with uterine serous carcinoma (USC).Materials and MethodsWe retrieved clinical
Autor:
Robert T. Morris, Rouba Ali-Fehmi, Julie J. Ruterbusch, Adnan R. Munkarah, Sara Rizk, Assaad Semaan, Ismail Mert, Sudeshna Bandyopadhyay, Michele L. Cote
Publikováno v:
Gynecologic Oncology. 124:265-269
Analyze tumor characteristics and outcomes in patients with endometrial carcinoma (EC)40 years of age and compare them to the characteristics of patients ≥ 40 years of age.10,700 patients (305 patients40 years of age) diagnosed between 1988 and 200