Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Aspasia Thodou Krokidi"'
Autor:
Thirupura S. Shankar, Dinesh K. A. Ramadurai, Kira Steinhorst, Salah Sommakia, Rachit Badolia, Aspasia Thodou Krokidi, Dallen Calder, Sutip Navankasattusas, Paulina Sander, Oh Sung Kwon, Aishwarya Aravamudhan, Jing Ling, Andreas Dendorfer, Changmin Xie, Ohyun Kwon, Emily H. Y. Cheng, Kevin J. Whitehead, Thomas Gudermann, Russel S. Richardson, Frank B. Sachse, Johann Schredelseker, Kenneth W. Spitzer, Dipayan Chaudhuri, Stavros G. Drakos
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
The authors found that VDAC2 plays a crucial role in influencing mitochondrial calcium dynamics and cellular calcium signalling. A VDAC2 agonist, efsevin, rescued the heart failure phenotype, identifying a new potential therapeutic target for heart f
Externí odkaz:
https://doaj.org/article/5def0b8a41bf407088eed68a7df3942d
Autor:
Rachit Badolia, Salah Sommakia, Aishwarya Aravamudhan, Aspasia Thodou Krokidi, Dipayan Chaudhuri, Thomas Gudermann, Paulina Sander, Kira Steinhorst, Ohyun Kwon, Stavros G. Drakos, Dinesh K. A. Ramadurai, Kenneth W. Spitzer, Sutip Navankasattusas, Andreas Dendorfer, Frank B. Sachse, Jing Ling, Emily H. Cheng, Thirupura S. Shankar, Johann Schredelseker, Dallen Calder, Kevin J. Whitehead, Changmin Xie, Oh Sung Kwon, Russel S. Richardson
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Nature Communications
Nature Communications
Voltage dependent anion channel 2 (VDAC2) is an outer mitochondrial membrane porin known to play a significant role in apoptosis and calcium signaling. Abnormalities in calcium homeostasis often leads to electrical and contractile dysfunction and can
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7d495aa6c7828ba2d150d39fc03e980
https://doaj.org/article/5def0b8a41bf407088eed68a7df3942d
https://doaj.org/article/5def0b8a41bf407088eed68a7df3942d
Autor:
Johann Schredelseker, Dipayan Chaudhuri, Ohyun Kwon, Dinesh K. A. Ramadurai, Kira Steinhorst, Dallen Calder, Salah Sommakia, Rachit Badolia, Thirupura S. Shankar, Emily Cheng, Sutip Navankasattusas, Aspasia Thodou Krokidi, Kenneth W. Spitzer, Frank B. Sachse, Stavros G. Drakos, Jing Ling, Russel S. Richardson
Publikováno v:
Circulation Research. 129
Voltage dependent anion channel 2 (VDAC2) is a mitochondrial outer membrane porin known to play a significant role in apoptosis and calcium signaling. Abnormalities in cellular calcium homeostasis often leads to electrical and contractile dysfunction
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::905add0c3f8705c9b62352ff04d34bb2
https://doi.org/10.1161/res.129.suppl_1.p467
https://doi.org/10.1161/res.129.suppl_1.p467
Autor:
Thirupura S. Shankar, Stephen H. McKellar, Craig H. Selzman, Dipayan Chaudhuri, Aspasia Thodou Krokidi, James C. Fang, Abdallah G. Kfoury, Iosif Taleb, Dinesh K. A. Ramadurai, E. Dale Abel, Peter Ferrin, Omar Wever-Pinzon, Rachit Badolia, Jared Rutter, Sutip Navankasattusas, Michael Yin, Stavros G. Drakos
Publikováno v:
Circulation
Background: Significant improvements in myocardial structure and function have been reported in some patients with advanced heart failure (termed responders [R]) following left ventricular assist device (LVAD)–induced mechanical unloading. This the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4787226c6ce50230915fc879ee9fb89a
https://pubmed.ncbi.nlm.nih.gov/32351122
https://pubmed.ncbi.nlm.nih.gov/32351122
Autor:
Ahmad A. Cluntun, Xuejing Yu, Corey N. Cunningham, Sarah Fogarty, Shannon Merx, Wojciech I. Swiatek, Bai Luo, Aspasia Thodou Krokidi, William L. Holland, Alex J. Bott, Gregory S. Ducker, Tyler Van Ry, Sophia Skedros, Kristofor A. Olson, Rachit Badolia, Sean M. Tatum, Stavros G. Drakos, Sandra Lettlova, Sutip Navankasattusas, Jared Rutter, Iosif Taleb, Nikolaos A. Diakos, Stephen H. McKellar, Thirupura S. Shankar, James E. Cox, Jordan A. Berg, K. Mark Parnell
Publikováno v:
Cell Metab
The metabolic rewiring of cardiomyocytes is a widely accepted hallmark of heart failure (HF). These metabolic changes include a decrease in mitochondrial pyruvate oxidation and an increased export of lactate. We identify the Mitochondrial Pyruvate Ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d68e7e4180bbb5a90d441073b0cc337d
https://doi.org/10.1016/j.cmet.2020.12.003
https://doi.org/10.1016/j.cmet.2020.12.003