Single-cell profiling of environmental enteropathy reveals signatures of epithelial remodeling and immune activation.

Autor: Kummerlowe C; Program in Computational and Systems Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.; Institute for Medical Engineering and Science (IMES), Department of Chemistry, and Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.; Ragon Institute of MGH, MIT and Harvard, Cambridge, MA 02139, USA.; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA., Mwakamui S; Tropical Gastroenterology and Nutrition Group, University of Zambia School of Medicine, Lusaka, Zambia., Hughes TK; Institute for Medical Engineering and Science (IMES), Department of Chemistry, and Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.; Ragon Institute of MGH, MIT and Harvard, Cambridge, MA 02139, USA.; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA., Mulugeta N; Institute for Medical Engineering and Science (IMES), Department of Chemistry, and Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.; Ragon Institute of MGH, MIT and Harvard, Cambridge, MA 02139, USA.; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA., Mudenda V; Tropical Gastroenterology and Nutrition Group, University of Zambia School of Medicine, Lusaka, Zambia., Besa E; Tropical Gastroenterology and Nutrition Group, University of Zambia School of Medicine, Lusaka, Zambia., Zyambo K; Tropical Gastroenterology and Nutrition Group, University of Zambia School of Medicine, Lusaka, Zambia., Shay JES; Institute for Medical Engineering and Science (IMES), Department of Chemistry, and Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.; Gastrointestinal Unit, Department of Medicine, Massachusetts General Hospital, Boston, MA 02114, USA., Fleming I; Institute for Medical Engineering and Science (IMES), Department of Chemistry, and Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.; Ragon Institute of MGH, MIT and Harvard, Cambridge, MA 02139, USA.; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA., Vukovic M; Institute for Medical Engineering and Science (IMES), Department of Chemistry, and Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.; Ragon Institute of MGH, MIT and Harvard, Cambridge, MA 02139, USA.; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA., Doran BA; Institute for Medical Engineering and Science (IMES), Department of Chemistry, and Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.; Ragon Institute of MGH, MIT and Harvard, Cambridge, MA 02139, USA.; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.; Department of Pathology, MGH, Harvard Medical School, Boston, MA 02115, USA., Aicher TP; Institute for Medical Engineering and Science (IMES), Department of Chemistry, and Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.; Ragon Institute of MGH, MIT and Harvard, Cambridge, MA 02139, USA.; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA., Wadsworth MH 2nd; Institute for Medical Engineering and Science (IMES), Department of Chemistry, and Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.; Ragon Institute of MGH, MIT and Harvard, Cambridge, MA 02139, USA.; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA., Bramante JT; Ragon Institute of MGH, MIT and Harvard, Cambridge, MA 02139, USA.; Department of Pathology, MGH, Harvard Medical School, Boston, MA 02115, USA.; University of Washington School of Medicine, Seattle, WA 98195, USA., Uchida AM; Division of Gastroenterology, Hepatology and Nutrition, Boston Children's Hospital, Boston, MA 02115, USA.; Cancer Immunology and Virology, Dana-Farber Cancer Institute, Boston, MA, 02115, USA.; Department of Medicine, Harvard Medical School, Boston, MA 02115, USA., Fardoos R; Africa Health Research Institute, Durban 4001, South Africa., Asowata OE; Cancer Immunology and Virology, Dana-Farber Cancer Institute, Boston, MA, 02115, USA.; Africa Health Research Institute, Durban 4001, South Africa.; Center for Biomedical Research, Population Council, Rockefeller University, New York, NY 10065, USA., Herbert N; Africa Health Research Institute, Durban 4001, South Africa., Yilmaz ÖH; Institute for Medical Engineering and Science (IMES), Department of Chemistry, and Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.; Department of Pathology, MGH, Harvard Medical School, Boston, MA 02115, USA., Kløverpris HN; Africa Health Research Institute, Durban 4001, South Africa.; School of Laboratory Medicine and Medical Sciences, University of KwaZulu-Natal, Durban 4041, South Africa.; Department of Immunology and Microbiology, University of Copenhagen, 1017 Copenhagen K, Denmark.; University College London, Division of Infection and Immunity, London WC1E 6BT, UK., Garber JJ; Department of Pathology, MGH, Harvard Medical School, Boston, MA 02115, USA.; Department of Medicine, Harvard Medical School, Boston, MA 02115, USA., Ordovas-Montañes J; Ragon Institute of MGH, MIT and Harvard, Cambridge, MA 02139, USA.; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.; Division of Gastroenterology, Hepatology and Nutrition, Boston Children's Hospital, Boston, MA 02115, USA.; Program in Immunology, Harvard Medical School, Boston, MA 02115, USA.; Harvard Stem Cell Institute, Cambridge, MA 02138, USA., Gartner ZJ; University of California San Francisco, San Francisco, CA 94185, USA.; Chan Zuckerberg Biohub, San Francisco, CA 94158, USA., Wallach T; Department of Pediatrics, SUNY Downstate Health Sciences University, Brooklyn, NY 11203, USA., Shalek AK; Program in Computational and Systems Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.; Institute for Medical Engineering and Science (IMES), Department of Chemistry, and Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.; Ragon Institute of MGH, MIT and Harvard, Cambridge, MA 02139, USA.; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.; Department of Medicine, Harvard Medical School, Boston, MA 02115, USA.; Program in Immunology, Harvard Medical School, Boston, MA 02115, USA., Kelly P; Tropical Gastroenterology and Nutrition Group, University of Zambia School of Medicine, Lusaka, Zambia.; Blizard Institute, Queen Mary University of London, London E1 2AT, UK.

Publikováno v: Science translational medicine [Sci Transl Med] 2022 Aug 31; Vol. 14 (660), pp. eabi8633. Date of Electronic Publication: 2022 Aug 31.

Will Africans take COVID-19 vaccination?

Autor: Anjorin AA; Department of Microbiology (Virology Research), Lagos State University, Lagos, Nigeria., Odetokun IA; Department of Veterinary Public Health & Preventive Medicine, University of Ilorin, Ilorin, Nigeria., Abioye AI; Harvard University, Boston, Massachusetts, United States of America., Elnadi H; Tours University, Tours, France., Umoren MV; Cincinnati Children's Hospital, Cincinnati, Ohio, United States of America., Damaris BF; Hannover Medical School, Hannover, Germany., Eyedo J; Department of Microbiology (Virology Research), Lagos State University, Lagos, Nigeria., Umar HI; Department of Biochemistry, Federal University of Technology, Akure, Ondo State, Nigeria., Nyandwi JB; Department of Pharmacy, University of Rwanda & Department of Pharmacology, College of Medicine, Gyeongsang National University, Gyeongsang, Republic of Korea., Abdalla MM; Department of Obstetrics and Gynaecology, Minya Health Insurance Hospital, Minya, Egypt., Tijani SO; Department of Medical Microbiology and Parasitology, College of Medicine University of Lagos, Idi Araba, Lagos, Nigeria., Awiagah KS; Accident and Emergency Centre, Korle Bu Teaching Hospital, Accra, Ghana., Idowu GA; Department of Mathematics, Lagos State University, Lagos, Nigeria., Fabrice SNA; Health Research Foundation, Buea, Cameroon., Maisara AMO; Department of Nephrology and Hemodialysis Center, Bahre Teaching Hospital, & Faculty of Medicine, International University of Africa, Khartoum, Sudan., Razouqi Y; Biological Engineering Laboratory, Sultan Moulay Slimane University Beni Mellal, Beni Mellal, Morocco., Mhgoob ZE; Department of Public Health & Infection Control, Aljawda Hospital & El Nileen University Community Development College, Khartoum, Sudan., Parker S; Division of Infectious Disease & HIV Medicine, University of Cape Town, Cape Town, South Africa., Asowata OE; Africa Health Research Institute, University of KwaZulu-Natal, Durban, South Africa., Adesanya IO; US Army Reserve & Hospitalist, BayouCity Physicians, Spring, Texas, United States of America., Obara MA; Hannover Medical School, Hannover, Germany., Jaumdally S; University of Cape Town Lung Institute, Cape Town, South Africa., Kitema GF; Department of Ophthalmology, University of Rwanda, Kigali, Rwanda.; St-Andrews University, St Andrews, United Kingdom., Okuneye TA; Department of Family Medicine, General Hospital Odan, Lagos, Nigeria., Mbanzulu KM; Department of Tropical Medicine, Parasitic and Infectious Diseases, University of Kinshasa, Kinshasa, Democratic Republic of Congo., Daitoni H; HIV and Malaria Research Unit, Malawi and Islamic Health Association of Malawi, Limbe, Malawi., Hallie EF; Department of Pharmacology and Toxicology, School of Pharmacy, University of Liberia, Monrovia, Liberia., Mosbah R; Infection Control Unit, Zagazig University, Zagazig, Egypt.; Faculty of Oral and Dental Medicine, Ahram Canadian University, 6th of October City, Egypt., Fasina FO; Department of Veterinary Tropical Diseases, Emergency Centre for Transboundary Animal Diseases (ECTAD), Food and Agricultural Organization of the United Nations (FAO), University of Pretoria, Pretoria, South Africa.

Publikováno v: PloS one [PLoS One] 2021 Dec 01; Vol. 16 (12), pp. e0260575. Date of Electronic Publication: 2021 Dec 01 (Print Publication: 2021).

HIV infection drives interferon signaling within intestinal SARS-CoV-2 target cells.

Autor: Fardoos R; Africa Health Research Institute, Durban, South Africa.; Department of Immunology and Microbiology, University of Copenhagen, Copenhagen, Denmark., Asowata OE; Africa Health Research Institute, Durban, South Africa.; School of Laboratory Medicine and Medical Sciences, University of KwaZulu-Natal, Durban, South Africa., Herbert N; Africa Health Research Institute, Durban, South Africa.; School of Laboratory Medicine and Medical Sciences, University of KwaZulu-Natal, Durban, South Africa., Nyquist SK; Institute for Medical Engineering & Science, Department of Chemistry, and Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology (MIT), Cambridge, Massachusetts, USA.; Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.; Ragon Institute of MGH, MIT and Harvard, Cambridge, Massachusetts, USA.; Program in Computational and Systems Biology, MIT, Cambridge, Massachusetts, USA., Zungu Y; Africa Health Research Institute, Durban, South Africa.; School of Laboratory Medicine and Medical Sciences, University of KwaZulu-Natal, Durban, South Africa., Singh A; Africa Health Research Institute, Durban, South Africa., Ngoepe A; Africa Health Research Institute, Durban, South Africa., Mbano IM; Africa Health Research Institute, Durban, South Africa.; School of Laboratory Medicine and Medical Sciences, University of KwaZulu-Natal, Durban, South Africa., Mthabela N; Africa Health Research Institute, Durban, South Africa., Ramjit D; Africa Health Research Institute, Durban, South Africa., Karim F; Africa Health Research Institute, Durban, South Africa., Kuhn W; ENT Department, General Justice Gizenga Mpanza Regional Hospital (Stanger Hospital), University of KwaZulu-Natal, Durban, South Africa., Madela FG; Discipline of General Surgery, Inkosi Albert Luthuli Central Hospital, University of KwaZulu-Natal, Durban, South Africa., Manzini VT; Discipline of General Surgery, Inkosi Albert Luthuli Central Hospital, University of KwaZulu-Natal, Durban, South Africa., Anderson F; Discipline of General Surgery, Inkosi Albert Luthuli Central Hospital, University of KwaZulu-Natal, Durban, South Africa., Berger B; Computer Science and Artificial Intelligence Laboratory and Department of Mathematics, MIT, Cambridge, Massachusetts, USA., Pers TH; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Shalek AK; Institute for Medical Engineering & Science, Department of Chemistry, and Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology (MIT), Cambridge, Massachusetts, USA.; Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.; Ragon Institute of MGH, MIT and Harvard, Cambridge, Massachusetts, USA., Leslie A; Africa Health Research Institute, Durban, South Africa.; School of Laboratory Medicine and Medical Sciences, University of KwaZulu-Natal, Durban, South Africa.; Division of Infection and Immunity, University College London, London, United Kingdom., Kløverpris HN; Africa Health Research Institute, Durban, South Africa.; Department of Immunology and Microbiology, University of Copenhagen, Copenhagen, Denmark.; School of Laboratory Medicine and Medical Sciences, University of KwaZulu-Natal, Durban, South Africa.; Division of Infection and Immunity, University College London, London, United Kingdom.

Publikováno v: JCI insight [JCI Insight] 2021 Aug 23; Vol. 6 (16). Date of Electronic Publication: 2021 Aug 23.

Comorbidities and the COVID-19 pandemic dynamics in Africa.

Autor: Anjorin AA; Department of Microbiology (Virology Research), Lagos State University, Ojo, Lagos, Nigeria., Abioye AI; Population Health Science Program & Department of Nutrition, Harvard T.H. Chan School of Public Health, Boston, MA, USA., Asowata OE; Africa Health Research Institute, Durban, South Africa.; School of Laboratory Medicine and Medical Sciences, University of KwaZulu-Natal, Durban, South Africa., Soipe A; Department of Medicine, Division of Nephrology, Upstate Medical University, Syracuse, NY, USA., Kazeem MI; Department of Biochemistry, Lagos State University, Ojo, Lagos, Nigeria., Adesanya IO; Bayou City Physicians, Houston, TX, USA., Raji MA; Department of Microbiology and Immunology, College of Medicine, Alfaisal University, Riyadh, Saudi Arabia., Adesanya M; Department of Microbiology and Immunology, College of Medicine, Alfaisal University, Riyadh, Saudi Arabia.; CPT US Army Reserve, Houston, TX, USA.; Nursing Department, University of Texas at Arlington, Arlington, TX, USA., Oke FA; Department of Internal Medicine, Brookdale University Hospital Medical Centre, New York City, NY, USA., Lawal FJ; Department of Infectious Diseases, Medical College of Georgia, Augusta University, Augusta, GA, USA., Kasali BA; Independent Researcher, Seattle, WA, USA., Omotayo MO; Centre for Global Health and Division of Pediatric Global Health, Massachusetts General Hospital, Boston, MA, USA.; Department of Pediatrics, Harvard Medical School, Boston, MA, USA.

Publikováno v: Tropical medicine & international health : TM & IH [Trop Med Int Health] 2021 Jan; Vol. 26 (1), pp. 2-13. Date of Electronic Publication: 2020 Oct 23.

Sustained gut dysbiosis and intestinal inflammation show correlation with weight gain in person with chronic HIV infection on antiretroviral therapy.

Autor: Ishizaka, Aya¹ (AUTHOR), Koga, Michiko¹ (AUTHOR), Mizutani, Taketoshi² (AUTHOR) mizutanitaketoshi@g.ecc.u-tokyo.ac.jp, Suzuki, Yutaka² (AUTHOR), Matano, Tetsuro^3,4 (AUTHOR), Yotsuyanagi, Hiroshi^1,5 (AUTHOR) yotsudid@ims.u-tokyo.ac.jp

Publikováno v: BMC Microbiology. 7/24/2024, p1-13. 13p.