Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Asne R. Bauskin"'
Autor:
Mary-Ann Murikami, Peter Bárány, Wei Luo, Lele Jiang, Juan Jesus Carrero, Shu Lin, Vicky Wang-Wei Tsai, Amanda Sainsbury, Samuel N. Breit, Fred S. Apple, Christopher P. Marquis, Laurence Macia, Herbert Herzog, Matthew Law, Tamara Kuffner, Liyun Wu, Nasreen Yagoutifam, Asne R. Bauskin, Olof Heimbürger, Peter Stenvinkel, David Brown
Publikováno v:
Nephrology Dialysis Transplantation. 27:70-75
Background Elevated macrophage inhibitory cytokine-1 (MIC-1/GDF15) levels in serum mediate anorexia and weight loss in some cancer patients and similarly elevated levels occur in chronic kidney disease (CKD). Serum MIC-1/GDF15 is also elevated in chr
Publikováno v:
Journal of Interferon & Cytokine Research. 30:389-397
Macrophage inhibitory cytokine-1/growth differentiation factor 15 (MIC-1/GDF15), a divergent member of the TGF-beta superfamily is induced by a range of proinflammatory cytokines and oxidized low-density lipoprotein (oxLDL) and is highly expressed in
Autor:
Savita Wakchoure, David Brown, Katri S. Selander, Teuvo Hentunen, Asne R. Bauskin, Telisha M. Swain, Katri S. Vuopala, Samuel N. Breit, Kevin W. Harris
Publikováno v:
The Prostate. 69:652-661
BACKGROUND Macrophage inhibitory cytokine-1 (MIC-1) belongs to the bone morphogenic protein/transforming growth factor-β (BMP/TGF-β) superfamily. Serum MIC-1 concentrations are elevated in patients with advanced prostate cancer. The effects of MIC-
Autor:
Malcolm D. Smith, Heiko Johnen, Paul P. Tak, Samuel N. Breit, Tom J. M. Smeets, Asne R. Bauskin, John Moore, David Brown, Tamara Kuffner, Helen Weedon, Sam Milliken
Publikováno v:
Arthritis and rheumatism, 56(3), 753-764. John Wiley and Sons Inc.
Objective The transforming growth factor β superfamily member macrophage inhibitory cytokine 1 (MIC-1) is expressed upon macrophage activation, regulated by the p53 pathway, and linked to clinical events in atherosclerosis and cancer. Since rheumato
Autor:
David Brown, Heiko Johnen, Asne R. Bauskin, Samuel N. Breit, Tamara Kuffner, Mark Hunter, X. Wei Luo
Publikováno v:
Cancer Research. 66:4983-4986
Macrophage inhibitory cytokine-1 (MIC-1), a transforming growth factor-β superfamily cytokine, is involved in tumor pathogenesis, and its measurement can be used as a clinical tool for the diagnosis and management of a wide range of cancers. Althoug
Autor:
David Brown, Jeffery D. Molkentin, Timothy E. Hewett, Jian Xu, Samuel N. Breit, John N. Lorenz, Raisa Klevitsky, Asne R. Bauskin, Thomas R. Kimball
Publikováno v:
Circulation Research. 98:342-350
Here we identified growth-differentiation factor 15 (GDF15) (also known as MIC-1), a secreted member of the transforming growth factor (TGF)-β superfamily, as a novel antihypertrophic regulatory factor in the heart. GDF15 is not expressed in the nor
Autor:
Janaki Amin, Mathew Law, Garret M. Hampton, Eleftherios P. Diamandis, Asne R. Bauskin, Mark Hunter, Klaus Jung, Graham G. Giles, David Brown, Robyn L. Ward, Carsten Stephan, Pamela J. Russell, Samuel N. Breit
Publikováno v:
Clinical Cancer Research. 12:89-96
Purpose: Current serum testing for the detection of prostate cancer (PCa) lacks specificity. On diagnosis, the optimal therapeutic pathway is not clear and tools for adequate risk assessment of localized PCa progression are not available. This leads
Autor:
Louise J. Brown, Greg J. Pankhurst, W. Douglas Fairlie, Paul M. G. Curmi, Asne R. Bauskin, Dene R. Littler, S. Pankhurst, Raffaella Tonini, Stephen J. Harrop, Matthew Z. DeMaere, Michele Mazzanti, Terence J. Campbell, Samuel N. Breit
Publikováno v:
Journal of Biological Chemistry. 279:9298-9305
Most proteins adopt a well defined three-dimensional structure; however, it is increasingly recognized that some proteins can exist with at least two stable conformations. Recently, a class of intracellular chloride ion channel proteins (CLICs) has b
Autor:
Jane A. Bursill, Philip W. Kuchel, Paramjit S. Bansal, Catherine E. Clarke, Jamie I. Vandenberg, Samuel N. Breit, Margaret Sunde, Allan M. Torres, Asne R. Bauskin, Terence J. Campbell, Paul F. Alewood, David Smith
Publikováno v:
Journal of Biological Chemistry. 278:42136-42148
The HERG K+ channel has very unusual kinetic behavior that includes slow activation but rapid inactivation. These features are critical for normal cardiac repolarization as well as in preventing lethal ventricular arrhythmias. Mutagenesis studies hav