Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Asmiti, Sura"'
Autor:
Mehaben Patel, Yorick Post, Natalie Hill, Asmiti Sura, Jay Ye, Trevor Fisher, Nicholas Suen, Mengrui Zhang, Leona Cheng, Ariel Pribluda, Hui Chen, Wen-Chen Yeh, Yang Li, Hélène Baribault, Russell B. Fletcher
Publikováno v:
Respiratory Research, Vol 25, Iss 1, Pp 1-12 (2024)
Abstract Background Wnt/β-catenin signaling is critical for lung development and AT2 stem cell maintenance in adults, but excessive pathway activation has been associated with pulmonary fibrosis, both in animal models and human diseases such as idio
Externí odkaz:
https://doaj.org/article/f27d31a51f9a492fa22352567892c341
Autor:
Jie Ding, Sung-Jin Lee, Lukas Vlahos, Kanako Yuki, Cara C. Rada, Vincent van Unen, Meghah Vuppalapaty, Hui Chen, Asmiti Sura, Aaron K. McCormick, Madeline Tomaske, Samira Alwahabi, Huy Nguyen, William Nowatzke, Lily Kim, Lisa Kelly, Douglas Vollrath, Andrea Califano, Wen-Chen Yeh, Yang Li, Calvin J. Kuo
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Derangements of the blood-brain barrier (BBB) or blood-retinal barrier (BRB) occur in disorders ranging from stroke, cancer, diabetic retinopathy, and Alzheimer’s disease. The Norrin/FZD4/TSPAN12 pathway activates WNT/β-catenin signaling,
Externí odkaz:
https://doaj.org/article/31df630cc0d74d1eb51da2d91c5e7f3c
Autor:
Hui Chen, Sung-Jin Lee, Ryan Li, Asmiti Sura, Nicholas Suen, Archana Dilip, Yan Pomogov, Meghah Vuppalapaty, Timothy T Suen, Chenggang Lu, Yorick Post, Yang Li
Publikováno v:
eLife, Vol 12 (2024)
Systemic toxicity is a major challenge in the development of therapeutics. Consequently, cell-type-specific targeting is needed to improve on-target efficacy while reducing off-target toxicity. Here, we describe a cell-targeting system we have termed
Externí odkaz:
https://doaj.org/article/b18a4fedb9594fe39bd8ab03b0fe2af9
Autor:
Liqin Xie, Russell B. Fletcher, Diksha Bhatia, Darshini Shah, Jacqueline Phipps, Shalaka Deshmukh, Haili Zhang, Jingjing Ye, Sungjin Lee, Lucas Le, Maureen Newman, Hui Chen, Asmiti Sura, Suhani Gupta, Laura E. Sanman, Fan Yang, Weixu Meng, Helene Baribault, Geertrui F. Vanhove, Wen-Chen Yeh, Yang Li, Chenggang Lu
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology. 14:435-464
Current management of inflammatory bowel disease leaves a clear unmet need to treat the severe epithelial damage. Modulation of Wnt signaling might present an opportunity to achieve histological remission and mucosal healing when treating IBD. Exogen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2328b014de90d749bf328ce57fad9c13
https://doi.org/10.1016/j.jcmgh.2022.05.003
https://doi.org/10.1016/j.jcmgh.2022.05.003
Autor:
Jie Ding, Sung-Jin Lee, Lukas Vlahos, Kanako Yuki, Cara C. Rada, Vincent van Unen, Meghah Vuppalapaty, Hui Chen, Asmiti Sura, Aaron K. McCormick, Madeline Tomaske, Samira Alwahabi, Huy Nguyen, William Nowatzke, Lily Kim, Lisa Kelly, Douglas Vollrath, Andrea J. Califano, Wen-Chen Yeh, Yang Li, Calvin J. Kuo
Derangements of the blood-brain barrier (BBB) or blood-retinal barrier (BRB) occur in disorders ranging from stroke, cancer, diabetic retinopathy, and Alzheimer’s disease. The Norrin/FZD4/TSPAN12 pathway activates WNT/β-catenin signaling, which is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::19bbbd11a56b64e460faffbbd6fab7fb
https://doi.org/10.1101/2022.10.13.510564
https://doi.org/10.1101/2022.10.13.510564
Autor:
Huy, Nguyen, Hui, Chen, Meghah, Vuppalapaty, Elizabeth, Whisler, Kelsey Ronarda, Logas, Parthasarathy, Sampathkumar, Russell Byron, Fletcher, Asmiti, Sura, Nicholas, Suen, Suhani, Gupta, Tom, Lopez, Jay, Ye, Shengjiang, Tu, Menaka, Bolaki, Wen-Chen, Yeh, Yang, Li, Sung-Jin, Lee
Publikováno v:
Translational Vision Science & Technology. 11:19
There remains a high unmet need for therapies with new mechanisms of action to achieve reperfusion of ischemic retina in diabetic retinopathy. We examined whether a novel frizzled class receptor 4 (FZD4) agonist could promote regeneration of function
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8ad1de27f5c99c1e91d27a01b5d7a97
https://doi.org/10.1167/tvst.11.9.19
https://doi.org/10.1167/tvst.11.9.19
Autor:
Russell Fletcher, Liqin Xie, Jacqueline L. Phipps, Laura E. Sanman, Shalaka Deshmukh, Darshini Shah, Natalie Hill, Angela Liu, Suhani Gupta, Asmiti Sura, Hui Chen, Jay Ye, Wen-Chen Yeh, Yang Li, Chenggang Lu
Publikováno v:
Gastroenterology. 162:S-78
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::75b5b348026ccbfe45761e214e1262da
https://doi.org/10.1016/s0016-5085(22)60198-7
https://doi.org/10.1016/s0016-5085(22)60198-7
Autor:
Chenggang Lu, Helene Baribault, Jacqueline Phipps, Jay Tibbitts, Suhani Gupta, Russell Fletcher, Hui Chen, Wen-Chen Yeh, Darshini Shah, Geertrui F. Vanhove, Mehaben Patel, Shalaka Deshmukh, Jay Ye, Asmiti Sura, Yang Li
Publikováno v:
Gastroenterology. 160:S-799
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::37a6092971541d2af36afb4f2221dd16
https://doi.org/10.1016/s0016-5085(21)02629-9
https://doi.org/10.1016/s0016-5085(21)02629-9
Autor:
Laura E. Sanman, Asmiti Sura, Wen-Chen Yeh, Shalaka Deshmukh, Jay Ye, Suhani Gupta, Darshini Shah, Liqin Xie, Chenggang Lu, Jacqueline Phipps, Ray Guigni, Hui Chen, Yang Li, Russell Fletcher
Publikováno v:
Gastroenterology. 160:S-233
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6dd52daae8a27406ad8b87f31a48c10b
https://doi.org/10.1016/s0016-5085(21)01296-8
https://doi.org/10.1016/s0016-5085(21)01296-8
Autor:
Wen-Chen Yeh, Yang Li, Zhong Huang, Asmiti Sura, Darshini Shah, Diksha Bhatia, Haili Zhang, Sung-Jin Lee, Brian Ouyang, Chenggang Lu, Hui Chen
Publikováno v:
Cell Chemical Biology. 27:598-609.e4
WNTs regulate myriad biological processes during embryonic development and are key regulators of stem cell function, tissue homeostasis, and injury repair in adults. The creation of WNT-based therapies has been hampered by challenges in developing so
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de68657bdaeba8e0ae994445293a435e
https://doi.org/10.1016/j.chembiol.2020.02.009
https://doi.org/10.1016/j.chembiol.2020.02.009