Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Asmerom T. Sengal"'
Autor:
Asmerom T. Sengal, Vanessa Bonazzi, Deborah Smith, Cristian P. Moiola, Rohan Lourie, Rebecca Rogers, Eva Colas, Antonio Gil-Moreno, Sophia Frentzas, Naven Chetty, Lewis Perrin, Pamela M. Pollock
Publikováno v:
npj Precision Oncology, Vol 7, Iss 1, Pp 1-18 (2023)
Abstract Endometrial cancer (EC) patients with metastatic/recurrent disease have limited treatment options and poor survival outcomes. Recently, we discovered the FGFR2c splice isoform is associated with poor prognosis in EC patients. Here we report
Externí odkaz:
https://doaj.org/article/b9b1b53e0c77425bb2b8f73a70dc9aaa
Autor:
Vanessa F. Bonazzi, Olga Kondrashova, Deborah Smith, Katia Nones, Asmerom T. Sengal, Robert Ju, Leisl M. Packer, Lambros T. Koufariotis, Stephen H. Kazakoff, Aimee L. Davidson, Priya Ramarao-Milne, Vanessa Lakis, Felicity Newell, Rebecca Rogers, Claire Davies, James Nicklin, Andrea Garrett, Naven Chetty, Lewis Perrin, John V. Pearson, Ann-Marie Patch, Nicola Waddell, Pamela M. Pollock
Publikováno v:
Genome Medicine, Vol 14, Iss 1, Pp 1-19 (2022)
Abstract Background Endometrial cancer (EC) is a major gynecological cancer with increasing incidence. It comprises four molecular subtypes with differing etiology, prognoses, and responses to chemotherapy. In the future, clinical trials testing new
Externí odkaz:
https://doaj.org/article/4b680dfc6fbc449d935cd19fb75a3b51
Autor:
Asmerom T Sengal, Deborah Smith, Cameron E Snell, Samuel Leung, Aline Talhouk, Elizabeth D Williams, Jessica N McAlpine, Pamela M Pollock
Publikováno v:
The Journal of Pathology: Clinical Research, Vol 8, Iss 6, Pp 521-537 (2022)
Abstract Endometrial carcinoma (EC) is the most common gynecological malignancy and fibroblast growth factor receptor 2 (FGFR2) is a frequently dysregulated receptor tyrosine kinase. FGFR2b and FGFR2c are the two main splice isoforms of FGFR2 and are
Externí odkaz:
https://doaj.org/article/4847d837df14472782a00eb999c1ccf3
Autor:
Pamela M. Pollock, Jessica N. McAlpine, Elizabeth D. Williams, Aline Talhouk, Samuel C.Y. Leung, Deborah S. Smith, Cameron E. Snell, Ann-Marie Patch, Asmerom T. Sengal
Supplementary Figures 1_6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14117600659185c4ff2a6a2a370fb12f
https://doi.org/10.1158/1078-0432.22477950.v1
https://doi.org/10.1158/1078-0432.22477950.v1
Autor:
A-M Patch, Andrea Garrett, Lambros T. Koufariotis, Asmerom T. Sengal, Leisl M. Packer, Priya Ramarao-Milne, Naven Chetty, Katia Nones, Felicity Newell, Deborah Smith, Vanessa Lakis, Aimee L Davidson, Robert J. Ju, Olga Kondrashova, James L. Nicklin, Rebecca Rogers, Vanessa F. Bonazzi, Pamela M. Pollock, Claire M. Davies, Lewis Perrin, John V. Pearson, Stephen H. Kazakoff, Nicola Waddell
BackgroundEndometrial cancer (EC) is a major gynecological cancer with increasing incidence. It comprised of four molecular subtypes with differing etiology, prognoses, and response to chemotherapy. In the future, clinical trials testing new single a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b57cb172bea0339f6a78562c3d0f253d
https://doi.org/10.1101/2021.03.30.436914
https://doi.org/10.1101/2021.03.30.436914
Autor:
Cameron Snell, Asmerom T. Sengal, Deborah Smith, Rebecca Rogers, Elizabeth D. Williams, Pamela M. Pollock
Publikováno v:
Cancers
Volume 13
Issue 7
Cancers, Vol 13, Iss 1703, p 1703 (2021)
Volume 13
Issue 7
Cancers, Vol 13, Iss 1703, p 1703 (2021)
Women with atypical hyperplasia (AH) or well-differentiated early-stage endometrioid endometrial carcinoma (EEC) who wish to retain fertility and/or with comorbidities precluding surgery, are treated with progestin. Clinically approved predictive bio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e5d8d1a64c193378a4e5893db13afc9
https://pubmed.ncbi.nlm.nih.gov/33916719
https://pubmed.ncbi.nlm.nih.gov/33916719
Autor:
Vanessa F. Bonazzi, Olga Kondrashova, Deborah Smith, Katia Nones, Asmerom T. Sengal, Robert Ju, Leisl M. Packer, Lambros T. Koufariotis, Stephen H. Kazakoff, Aimee L. Davidson, Priya Ramarao-Milne, Vanessa Lakis, Felicity Newell, Rebecca Rogers, Claire Davies, James Nicklin, Andrea Garrett, Naven Chetty, Lewis Perrin, John V. Pearson, Ann-Marie Patch, Nicola Waddell, Pamela M. Pollock
Publikováno v:
Genome Medicine
Genome Medicine, Vol 14, Iss 1, Pp 1-19 (2022)
Genome Medicine, Vol 14, Iss 1, Pp 1-19 (2022)
Background Endometrial cancer (EC) is a major gynecological cancer with increasing incidence. It comprises four molecular subtypes with differing etiology, prognoses, and responses to chemotherapy. In the future, clinical trials testing new single ag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::328f669720875c73e354033fe79df4de
https://pubmed.ncbi.nlm.nih.gov/35012638
https://pubmed.ncbi.nlm.nih.gov/35012638
Autor:
Asmerom T Sengal, Vanessa Bonazzi, Olga Kondrashova, Lewis Perrin, Naven Chetty, Deborah Smith, Antonio Gil-Moreno, Eva Colas, Pamela M Pollock
Publikováno v:
Molecular Cancer Therapeutics. 20:LBA020-LBA020
Purpose: Endometrial cancer (EC) is the most frequently diagnosed gynaecological cancer. The majority of women with EC are treated surgically and have a good outcome, however 25-30% of patients presenting with metastases or recurrent disease do not h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::26551512113fd041ec3a2b49ad681f3d
https://doi.org/10.1158/1535-7163.targ-21-lba020
https://doi.org/10.1158/1535-7163.targ-21-lba020
Autor:
Pamela M. Pollock, Cameron Snell, Rebecca Rogers, Asmerom T. Sengal, Deborah A. Smith, Elizabeth D. Williams
Publikováno v:
Clinical Cancer Research. 27:PO033-PO033
Introduction: Women with atypical hyperplasia (AH) or well-differentiated endometrioid endometrial carcinoma (EEC) who wish to retain fertility and/or with severe comorbidities that preclude surgery, are treated with progestin. Previously, we reporte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::038c1281de3c10c1dfa2a7b4f4b5c69a
https://doi.org/10.1158/1557-3265.endomet20-po033
https://doi.org/10.1158/1557-3265.endomet20-po033
Autor:
Andrea Garrett, Katia Nones, Naven Chetty, Deborah A. Smith, Vanessa F. Bonazzi, Lambros T. Koufariotis, Aimee L Davidson, Rebecca Rogers, Robert J. Ju, Asmerom T. Sengal, Lewis Perrin, John F. Pearson, Priya Ramarao-Milne, Pamela M. Pollock, Ann-Marie Patch, Vanessa Lakis, Olga Kondrashova, Felicity Newell, Leisl M. Packer, James L. Nicklin, Claire M. Davies, Stephen H. Kazakoff, Nicola Waddell
Publikováno v:
Clinical Cancer Research. 27:PR007-PR007
Endometrial cancer is a major gynaecological cancer with a high incidence resulting in over 500 Australian women dying every year. Good pre-clinical models are urgently needed to study the biology of this disease, and to develop and test novel treatm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1c355c98c1e9f91600a70f33e4ac858a
https://doi.org/10.1158/1557-3265.endomet20-pr007
https://doi.org/10.1158/1557-3265.endomet20-pr007