Vγ9Vδ2 T cell activation by strongly agonistic nucleotidic phosphoantigens

Autor: Eric Champagne, Asmaa Mehtougui, Erin J. Adams, Javier Alguacil, Suzanne Peyrottes, Morgane Moulin, Siyi Gu

Publikováno v: Cellular and Molecular Life Sciences
Cellular and Molecular Life Sciences, Springer Verlag, 2017, 74 (23), pp.4353-4367. ⟨10.1007/s00018-017-2583-0⟩

Human Vγ9Vδ2 T cells can sense through their TCR tumor cells producing the weak endogenous phosphorylated antigen isopentenyl pyrophosphate (IPP), or bacterially infected cells producing the strong agonist hydroxyl dimethylallyl pyrophosphate (HDMA

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::229074718b17c9fc35e3449b5a26162c
https://hal.archives-ouvertes.fr/hal-02408365