Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Asmaa Hachim"'
Autor:
Jaime S. Rosa Duque, Xiwei Wang, Daniel Leung, Samuel M. S. Cheng, Carolyn A. Cohen, Xiaofeng Mu, Asmaa Hachim, Yanmei Zhang, Sau Man Chan, Sara Chaothai, Kelvin K. H. Kwan, Karl C. K. Chan, John K. C. Li, Leo L. H. Luk, Leo C. H. Tsang, Wilfred H. S. Wong, Cheuk Hei Cheang, Timothy K. Hung, Jennifer H. Y. Lam, Gilbert T. Chua, Winnie W. Y. Tso, Patrick Ip, Masashi Mori, Niloufar Kavian, Wing Hang Leung, Sophie Valkenburg, Malik Peiris, Wenwei Tu, Yu Lung Lau
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
There are adverse events associated with COVID-19 vaccines, such as myocarditis for adolescents following receipt of SARS-CoV-2 mRNA vaccines. Here the authors compare the immunogenicity and reactogenicity of two widely available SARS-CoV-2 vaccines
Externí odkaz:
https://doaj.org/article/f4b9f38e2cf744f5a91a3b8ac36a6c70
Autor:
Asmaa Hachim, Haogao Gu, Otared Kavian, Masashi Mori, Mike Y. W. Kwan, Wai Hung Chan, Yat Sun Yau, Susan S. Chiu, Owen T. Y. Tsang, David S. C. Hui, Chris K. P. Mok, Fionn N. L. Ma, Eric H. Y. Lau, Gaya K. Amarasinghe, Abraham J. Qavi, Samuel M. S. Cheng, Leo L. M. Poon, J. S. Malik Peiris, Sophie A. Valkenburg, Niloufar Kavian
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
The antibody response of children to SARS-CoV-2 is less well studied than in adults. Here Hachim et al. show that children have reduced antibody levels to structural proteins and suggest that the predominance of antibody responses to non-structural p
Externí odkaz:
https://doaj.org/article/aed0696ee41047fda9efd9c5bf8bf330
Autor:
Carolyn A. Cohen, Athena P. Y. Li, Asmaa Hachim, David S. C. Hui, Mike Y. W. Kwan, Owen T. Y. Tsang, Susan S. Chiu, Wai Hung Chan, Yat Sun Yau, Niloufar Kavian, Fionn N. L. Ma, Eric H. Y. Lau, Samuel M. S. Cheng, Leo L. M. Poon, Malik Peiris, Sophie A. Valkenburg
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Why children are generally less susceptible than adults to COVID-19 is unclear and has not extensively been examined longitudinally. Here the authors compare antibodies, cytokines and immune cell responses in adults and children over 6 months post-in
Externí odkaz:
https://doaj.org/article/4a06b354eca4474d953f5855491515f4
Publikováno v:
Emerging Infectious Diseases, Vol 27, Iss 12, Pp 3173-3175 (2021)
The infectivity of severe acute respiratory syndrome coronavirus 2 in deceased persons and organisms remains unclear. We studied transgenic K18 hACE2 mice to determine the kinetics of virus infectivity after host death. Five days after death, virus i
Externí odkaz:
https://doaj.org/article/33d483af54364b9b8169613a2ccb12cf
Autor:
Chao Wu, Abraham J. Qavi, Austin B. Moyle, Nicole D. Wagner, Asmaa Hachim, Niloufar Kavian, Aidan R. Cole, Joyce Sweeney-Gibbons, Henry W. Rohrs, J.S. Malik Peiris, Christopher F. Basler, Michael L. Gross, Sophie A. Valkenburg, Christopher W. Farnsworth, Gaya K. Amarasinghe, Daisy W. Leung
Publikováno v:
STAR Protocols, Vol 2, Iss 4, Pp 100906- (2021)
Summary: Nucleocapsid proteins are essential for SARS-CoV-2 life cycle. Here, we describe protocols to gather domain-specific insights about essential properties of nucleocapsids. These assays include dynamic light scattering to characterize oligomer
Externí odkaz:
https://doaj.org/article/e32263235f994b63906d2a8175965a34
Autor:
Thi H. O. Nguyen, Carolyn A. Cohen, Louise C. Rowntree, Maireid B. Bull, Asmaa Hachim, Katherine Kedzierska, Sophie A. Valkenburg
Publikováno v:
Frontiers in Medicine, Vol 8 (2021)
T cell responses are a key cornerstone to viral immunity to drive high-quality antibody responses, establishing memory for recall and for viral clearance. Inefficient recruitment of T cell responses plays a role in the development of severe COVID-19
Externí odkaz:
https://doaj.org/article/bc9ee59db72b419eb4d06a615c8602be
Autor:
Paul K.S. Chan, Grace Lui, Asmaa Hachim, Ronald L.W. Ko, Siaw S. Boon, Timothy Li, Niloufar Kavian, Fion Luk, Zigui Chen, Emily M. Yau, Kin H. Chan, Chi-hang Tsang, Samuel M.S. Cheng, Daniel K.W. Chu, Ranawaka A.P.M. Perera, Wendy C.S. Ho, Apple C.M. Yeung, Chit Chow, Leo L.M. Poon, Sophie A. Valkenburg, David S.C. Hui, Malik Peiris
Publikováno v:
Emerging Infectious Diseases, Vol 26, Iss 12, Pp 3076-3078 (2020)
In March 2020, mild signs and symptoms of coronavirus disease developed in a healthy 33-year-old man in Hong Kong. His first infection did not produce virus neutralizing antibodies. In August, he had asymptomatic reinfection, suggesting that persons
Externí odkaz:
https://doaj.org/article/784946f56f33434aa0a8f00946c5624c
Autor:
Chao Wu, Abraham J. Qavi, Asmaa Hachim, Niloufar Kavian, Aidan R. Cole, Austin B. Moyle, Nicole D. Wagner, Joyce Sweeney-Gibbons, Henry W. Rohrs, Michael L. Gross, J. S. Malik Peiris, Christopher F. Basler, Christopher W. Farnsworth, Sophie A. Valkenburg, Gaya K. Amarasinghe, Daisy W. Leung
Publikováno v:
iScience, Vol 24, Iss 6, Pp 102681- (2021)
Summary: Nucleocapsid (N) encoded by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) plays key roles in the replication cycle and is a critical serological marker. Here, we characterize essential biochemical properties of N and describe
Externí odkaz:
https://doaj.org/article/71038b426324461c9d77c5db5fc76df9
Autor:
Jaime S. Rosa Duque, Xiwei Wang, Daniel Leung, Samuel M. S. Cheng, Carolyn A. Cohen, Xiaofeng Mu, Asmaa Hachim, Yanmei Zhang, Sau Man Chan, Sara Chaothai, Kelvin K. H. Kwan, Karl C. K. Chan, John K. C. Li, Leo L. H. Luk, Leo C. H. Tsang, Wilfred H. S. Wong, Cheuk Hei Cheang, Timothy K. Hung, Jennifer H. Y. Lam, Gilbert T. Chua, Winnie W. Y. Tso, Patrick Ip, Masashi Mori, Niloufar Kavian, Wing Hang Leung, Sophie Valkenburg, Malik Peiris, Wenwei Tu, Yu Lung Lau
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-1 (2022)
Externí odkaz:
https://doaj.org/article/e0161bcd3cb542a29c245989383f4cf8
Publikováno v:
Clinical & Translational Immunology, Vol 10, Iss 6, Pp n/a-n/a (2021)
Abstract Objectives Current inactivated influenza vaccines provide suboptimal protection against antigenic drift, and repeated annual vaccinations shape antibody specificity but the effect on protection from infection is not well understood. Methods
Externí odkaz:
https://doaj.org/article/d46cb13abfd64259a8f9d4192437a9da