Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Asmaa El-Kenawi"'
Autor:
Hao Wu, Veronica Estrella, Matthew Beatty, Dominique Abrahams, Asmaa El-Kenawi, Shonagh Russell, Arig Ibrahim-Hashim, Dario Livio Longo, Yana K. Reshetnyak, Anna Moshnikova, Oleg A. Andreev, Kimberly Luddy, Mehdi Damaghi, Krithika Kodumudi, Smitha R. Pillai, Pedro Enriquez-Navas, Shari Pilon-Thomas, Pawel Swietach, Robert J. Gillies
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
T-cell activation primarily occurs in the lymph nodes, highly organized and specialized secondary lymphoid organs. Here the authors show that the acidic extracellular pH in lymph node paracortical zones limits cytokine production by effector T-cells,
Externí odkaz:
https://doaj.org/article/8a725d35fbca44839f00a263e2a935bc
Autor:
Nicholas H Chakiryan, Gregory J Kimmel, Youngchul Kim, Ali Hajiran, Ahmet M Aydin, Logan Zemp, Esther Katende, Jonathan Nguyen, Neale Lopez-Blanco, Jad Chahoud, Philippe E Spiess, Michelle Fournier, Jasreman Dhillon, Liang Wang, Carlos Moran-Segura, Asmaa El-Kenawi, James Mulé, Philipp M Altrock, Brandon J Manley
Publikováno v:
PLoS ONE, Vol 16, Iss 4, p e0245415 (2021)
Immune infiltration is typically quantified using cellular density, not accounting for cellular clustering. Tumor-associated macrophages (TAM) activate oncogenic signaling through paracrine interactions with tumor cells, which may be better reflected
Externí odkaz:
https://doaj.org/article/805e9012c35c46a7a9bcfa1b146ddd89
Autor:
Asmaa El-Kenawi, Anders Berglund, Veronica Estrella, Yonghong Zhang, Min Liu, Ryan M. Putney, Sean J. Yoder, Joseph Johnson, Joel Brown, Robert Gatenby
Publikováno v:
Cancer Research. 83:720-734
Induction of cell death represents a primary goal of most anticancer treatments. Despite the efficacy of such approaches, a small population of “persisters” develop evasion strategies to therapy-induced cell death. While previous studies have ide
Autor:
Brian Ruffell, Robert A. Gatenby, Kosj Yamoah, John M. Koomen, Xiaoqing Yu, Robert J. Gillies, Jasreman Dhillon, Amparo N. Serna, Leenil Noel, KayLee K. Steiner, Aysenur Keske, Julieta Abraham-Miranda, Shivanshu Awasthi, Min Liu, William Dominguez-Viqueira, Asmaa El-Kenawi
Castration-resistant prostate cancer (CRPC) is a lethal stage of disease in which androgen receptor (AR) signaling is persistent despite androgen deprivation therapy (ADT). Most studies have focused on investigating cell-autonomous alterations in CRP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ea51d3dbf021bef272ce167a1a2594f
https://doi.org/10.1158/0008-5472.c.6513003
https://doi.org/10.1158/0008-5472.c.6513003
Autor:
Robert Gatenby, Joel Brown, Joseph Johnson, Sean J. Yoder, Ryan M. Putney, Min Liu, Yonghong Zhang, Veronica Estrella, Anders Berglund, Asmaa El-Kenawi
Induction of cell death represents a primary goal of most anticancer treatments. Despite the efficacy of such approaches, a small population of “persisters” develop evasion strategies to therapy-induced cell death. While previous studies have ide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c056409d8acb774d2019af55e1a902e
https://doi.org/10.1158/0008-5472.c.6514344.v1
https://doi.org/10.1158/0008-5472.c.6514344.v1
Autor:
Brian Ruffell, Robert A. Gatenby, Kosj Yamoah, John M. Koomen, Xiaoqing Yu, Robert J. Gillies, Jasreman Dhillon, Amparo N. Serna, Leenil Noel, KayLee K. Steiner, Aysenur Keske, Julieta Abraham-Miranda, Shivanshu Awasthi, Min Liu, William Dominguez-Viqueira, Asmaa El-Kenawi
Key resources
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1146d13364523cfaba7a775335f33fa
https://doi.org/10.1158/0008-5472.22428375
https://doi.org/10.1158/0008-5472.22428375
Autor:
Brian Ruffell, Robert A. Gatenby, Kosj Yamoah, John M. Koomen, Xiaoqing Yu, Robert J. Gillies, Jasreman Dhillon, Amparo N. Serna, Leenil Noel, KayLee K. Steiner, Aysenur Keske, Julieta Abraham-Miranda, Shivanshu Awasthi, Min Liu, William Dominguez-Viqueira, Asmaa El-Kenawi
Abundance of lipids in macrophages and importance of mevalonate pathway in prostate cancer cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6987b0f8d935deb045fef4b86ba7bda8
https://doi.org/10.1158/0008-5472.22428387
https://doi.org/10.1158/0008-5472.22428387
Supplementary Data from Elevated Methionine Flux Drives Pyroptosis Evasion in Persister Cancer Cells
Autor:
Robert Gatenby, Joel Brown, Joseph Johnson, Sean J. Yoder, Ryan M. Putney, Min Liu, Yonghong Zhang, Veronica Estrella, Anders Berglund, Asmaa El-Kenawi
Supplemental Materials Methods with additional references.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d4c4627d5ddc7e6723b44c9bbd02693
https://doi.org/10.1158/0008-5472.22433337
https://doi.org/10.1158/0008-5472.22433337
Autor:
Brian Ruffell, Robert A. Gatenby, Kosj Yamoah, John M. Koomen, Xiaoqing Yu, Robert J. Gillies, Jasreman Dhillon, Amparo N. Serna, Leenil Noel, KayLee K. Steiner, Aysenur Keske, Julieta Abraham-Miranda, Shivanshu Awasthi, Min Liu, William Dominguez-Viqueira, Asmaa El-Kenawi
Additional details on LC-MS/MS sample preparation and RNA sequencing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::305aabaf3cd3f180ca58a00bfd1894a7
https://doi.org/10.1158/0008-5472.22428378.v1
https://doi.org/10.1158/0008-5472.22428378.v1
Autor:
Asmaa El-Kenawi, Ryan Putney, Shivanshu Awasthi, Amparo Serna, Corrado Caslini, Jasreman Dhillon, Kosj Yamoah
Publikováno v:
Cancer Research. 83:1956-1956
Prostate cancer (PCa) is the second leading cause of cancer-related death in men in United States. African American men (AAM) have higher rates of PCa incidence and mortality compared with European American men (EAM). While socioeconomics, access to