Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Asma S. Al-Amoodi"'
Autor:
Asma S. Al-Amoodi, Jing Kai, Yanyan Li, Jana S. Malki, Abdullah Alghamdi, Arwa Al-Ghuneim, Alfonso Saera-Vila, Satoshi Habuchi, Jasmeen S. Merzaban
Publikováno v:
iScience, Vol 27, Iss 2, Pp 108882- (2024)
Summary: For almost two decades, clinicians have overlooked the diagnostic potential of CD34neg hematopoietic stem cells because of their limited homing capacity relative to CD34posHSCs when injected intravenously. This has contributed to the lack of
Externí odkaz:
https://doaj.org/article/c801343de13e4f5c9345460b3766853c
Autor:
Ioannis Isaioglou, Mansour M. Aldehaiman, Yanyan Li, Abdellatif Ait Lahcen, Sakandar Rauf, Asma S. Al-Amoodi, Umme Habiba, Abdullah Alghamdi, Shuho Nozue, Satoshi Habuchi, Khaled N. Salama, Jasmeen S. Merzaban
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Exosomes are tiny vesicles released by cells that carry communications to local and distant locations. Emerging research has revealed the role played by integrins found on the surface of exosomes in delivering information once they reach their destin
Externí odkaz:
https://doaj.org/article/0b4c756834594199bd5ff9b99d159032
Autor:
Bader Al Alwan, Karmen AbuZineh, Shuho Nozue, Aigerim Rakhmatulina, Mansour Aldehaiman, Asma S. Al-Amoodi, Maged F. Serag, Fajr A. Aleisa, Jasmeen S. Merzaban, Satoshi Habuchi
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-14 (2021)
Al Alwan et al. describe the tethering and rolling behaviour of leukemic cells by using a microfluidic platform that mimics the endothelial surface under flow conditions. With single-molecule live cell fluorescence imaging, they show that unique spat
Externí odkaz:
https://doaj.org/article/db5aefcd77744f5b97409746ef597d78
Autor:
Dina B. AbuSamra, Fajr A. Aleisa, Asma S. Al-Amoodi, Heba M. Jalal Ahmed, Chee Jia Chin, Ayman F. Abuelela, Ptissam Bergam, Rachid Sougrat, Jasmeen S. Merzaban
Publikováno v:
Blood Advances, Vol 1, Iss 27, Pp 2799-2816 (2017)
Abstract: CD34 is routinely used to identify and isolate human hematopoietic stem/progenitor cells (HSPCs) for use clinically in bone marrow transplantation, but its function on these cells remains elusive. Glycoprotein ligands on HSPCs help guide th
Externí odkaz:
https://doaj.org/article/05774d7f6f8c4c16845a5cd53a787445
Autor:
Abdullah Alghamdi, Amar Tamra, Aigerim Rakhmatulina, Shuho Nozue, Asma S. Al-Amoodi, Mansour M. Aldehaiman, Ioannis Isaioglou, Jasmeen S. Merzaban, Satoshi Habuchi
Publikováno v:
Analytical Chemistry. 95:1958-1966
Autor:
Asma S. Al-Amoodi, Yanyan Li, Arwa Al-Ghuneim, Hanaa Allehaibi, Ioannis Isaioglou, Luke E. Esau, Dina B. AbuSamra, Jasmeen S. Merzaban
Publikováno v:
Blood Advances. 6:4373-4391
In contrast to the short-term (ST) CD34+ stem cells, studies have suggested that long-term (LT) hematopoietic stem cells (HSCs) found in the CD34− stem cell pool have trouble migrating and engrafting when introduced through IV. To understand why th
Publikováno v:
Analytical Chemistry. 92:6200-6206
The parallel plate flow chamber assay is widely utilized to study physiological cell-cell adhesive interactions under dynamic flow that mimics the bloodstream. In this technique, the cells are perfused under defined shear stresses over a monolayer of
Autor:
Muhammad Tehseen, Mo Li, Amal J. Ali, Kosuke Sakashita, Juan Carlos Izpisua Belmonte, Asma S. Al-Amoodi, Jasmeen S. Merzaban, Jae Man Lee, Ruoyu Zhou, Takahiro Kusakabe
Publikováno v:
Biochemistry. 59(39)
Recruitment of circulating cells toward target sites is primarily dependent on selectin/ligand adhesive interactions. Glycosyltransferases are involved in the creation of selectin ligands on proteins and lipids. α1,3-Fucosylation is imperative for t
Autor:
Maged F. Serag, Fajr A. Aleisa, Asma S. Al-Amoodi, Mansour Aldehaiman, Shuho Nozue, Satoshi Habuchi, Jasmeen S. Merzaban, Aigerim Rakhmatulina, Bader Al Alwan, Karmen AbuZineh
Publikováno v:
SSRN Electronic Journal.
Hematopoietic stem/progenitor cell (HSPC) homing is initiated by tethering and rolling of the cells on endothelium through selectin-ligand interactions. Although multiple factors that affect the rolling behaviour of the cells have been identified, mo
Autor:
Jasmeen S. Merzaban, Hanaa Allehaibi, Arwa A Alghuneim, Yanyan Li, Luke Esau, Asma S. Al-Amoodi
Publikováno v:
Blood. 138:1084-1084
CD34 has traditionally been used as a marker to enrich human bone marrow stem cells for clinical bone marrow transplants for over five decades. However, several studies support that the most primitive hematopoietic stem cells (HSCs) responsible for l