Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Asma Rizvi"'
Publikováno v:
The Journal of Biological Chemistry
Macroautophagy dysregulation is implicated in multiple neurological disorders, such as Parkinson's disease. While autophagy pathways are heavily researched in heterologous cells and neurons, regulation of autophagy in the astrocyte, the most abundant
Autor:
James M. Slater, James D. Crapo, Michael J. Pecaut, Asma Rizvi, T. L. Freeman, Shalini Mehrotra, Daila S. Gridley, Xian Luo-Owen
Publikováno v:
Technology in Cancer Research & Treatment. 11:447-457
Due to radiation-induced immune depression and development of pathologies such as cancer, there is increasing urgency to identify radiomitigators that are effective when administered after radiation exposure. The main goal of this study was to determ
Autor:
Jian Tian, Asma Rizvi, Michael J. Pecaut, Adeola Y. Makinde, Xian Luo-Owen, Xiao Wen Mao, Jason M. Slater, Daila S. Gridley
Publikováno v:
International Journal of Radiation Biology. 89:26-35
The major goal was to evaluate effects of various radiation regimens on leukocyte populations relatively long-term after whole-body irradiation.C57BL/6 mice were exposed to-low-dose/low-dose rate (LDR) (57)Co γ-rays (0.01 Gy, 0.03 cGy/h), with and w
Publikováno v:
Journal of Radiation Research. 52:701-711
The goal was to investigate the T helper (Th) response in splenocytes of mice exposed to low-dose/low-dose-rate (LDR) γ-rays, simulated solar particle event protons (sSPE), or combination of both. C57BL/6 mice were exposed to LDR γ-radiation ((57)C
Publikováno v:
Journal of Radiation Research. 50:139-150
A better understanding of low dose radiation effects is needed to accurately estimate health risks. In this study, C57BL/6 mice were gamma-irradiated to total doses of 0, 0.01, 0.05, and 0.1 Gy ((57)Co; ~0.02 cGy/h). Subsets per group were euthanized
Autor:
Louis S. Stodieck, Michael J. Pecaut, Asma Rizvi, James M. Slater, Virginia L. Ferguson, Daila S. Gridley, Stephen K. Chapes, Xian Luo-Owen
Publikováno v:
Journal of Applied Physiology. 106:194-202
The immune system is highly sensitive to stressors present during spaceflight. The major emphasis of this study was on the T lymphocytes in C57BL/6NTac mice after return from a 13-day space shuttle mission (STS-118). Spleens and thymuses from flight
Autor:
Daila S. Gridley, Farnaz P. Baqai, Xian Luo-Owen, Asma Rizvi, Peter Koss, George Coutrakon, Michael J. Pecaut, James M. Slater, Adeola Y. Makinde, Erben J. M. Bayeta
Publikováno v:
Radiation Research. 169:280-287
The health consequences of exposure to low-dose radiation combined with a solar particle event during space travel remain unresolved. The goal of this study was to determine whether protracted radiation exposure alters gene expression and oxidative b
Publikováno v:
Radiation research. 177(3)
Health risks due to exposure to low-dose/low-dose-rate radiation alone or when combined with acute irradiation are not yet clearly defined. This study quantified the effects of protracted exposure to low-dose/low-dose-rate γ rays with and without ac
Publikováno v:
International journal of radiation biology. 87(1)
Astronauts on missions are exposed to low-dose/low-dose-rate (LDR) radiation and could receive high doses during solar particle events (SPE). This study investigated T cell function in response to LDR radiation and simulated SPE (sSPE) protons, alone
Autor:
Daila S. Gridley, Asma Rizvi, Michael J. Pecaut, James M. Slater, Xian Luo-Owen, Xiao Wen Mao, Adeola Y. Makinde
Publikováno v:
Technology in cancer researchtreatment. 9(6)
Radiation is a major factor in the spaceflight environment that has carcinogenic potential. Astronauts on missions are continuously exposed to low-dose/low-dose-rate (LDR) radiation and may receive relatively high doses during a solar particle event