Zobrazeno 1 - 10
of 89
pro vyhledávání: '"Asma Naseem"'
Autor:
Asma Naseem, Alessia Cavazza
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 32, Iss 2, Pp 101247- (2024)
Externí odkaz:
https://doaj.org/article/fc9a2e93064a45d6a20a7856fe0cdbc5
Autor:
Rajeev Rai, Asma Naseem, Winston Vetharoy, Zohar Steinberg, Adrian J. Thrasher, Giorgia Santilli, Alessia Cavazza
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 29, Iss , Pp 58-69 (2023)
Gene editing has emerged as a powerful tool for the therapeutic correction of monogenic diseases. CRISPR-Cas9 applied to hematopoietic stem and progenitor cells (HSPCs) has shown great promise in proof-of-principle preclinical studies to treat hemato
Externí odkaz:
https://doaj.org/article/6ed43264111a4d30ac2fe0ab9f484c6d
Publikováno v:
STAR Protocols, Vol 4, Iss 3, Pp 102466- (2023)
Summary: Oil red O staining is effective in detection and quantification of neutral lipid droplets in tissues such as the liver. However, converting images into testable data using ImageJ can be time-consuming and is prone to inaccuracy or bias. We d
Externí odkaz:
https://doaj.org/article/e2dfea933e7344ec8063b3ba8ca85afc
Publikováno v:
Birds, Vol 3, Iss 3, Pp 245-259 (2022)
The visual perception of birds is an incredibly exciting subject of research. Birds have significantly higher visual acuity than most other animals, which helps them stay safe in flight and detect their prey. Understanding how the eyes send informati
Externí odkaz:
https://doaj.org/article/2624c8b483cb4b568d722a810f42b8fb
Genome editing for primary immunodeficiencies: A therapeutic perspective on Wiskott-Aldrich syndrome
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Primary immunodeficiency diseases (PIDs) are a group of rare inherited disorders affecting the immune system that can be conventionally treated with allogeneic hematopoietic stem cell transplantation and with experimental autologous gene therapy. Wit
Externí odkaz:
https://doaj.org/article/8d5056c083864ea59672544751a530e9
Autor:
Hashim Ali, Miguel Mano, Luca Braga, Asma Naseem, Bruna Marini, Diem My Vu, Chiara Collesi, Germana Meroni, Marina Lusic, Mauro Giacca
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
HIV-1 integration into host DNA is mediated by the viral integrase (IN). Here, using siRNA screen and high-content microscopy, the authors identify the host E3 RING ligase TRIM33 to affect IN stability and show that TRIM33 prevents viral integration
Externí odkaz:
https://doaj.org/article/f93cc3e0668a4faa96dbc3035b454cec
Autor:
Adrian H. Heald, David A. Jenkins, Richard Williams, Rajshekhar N. Mudaliar, Asma Naseem, Kelly A. Bowden Davies, J. Martin Gibson, Yonghong Peng, William Ollier
Publikováno v:
Heald, A, Jenkins, D A, Williams, R, Mudaliar, R, Naseem, A, Bowden Davies, K A, Gibson, M, Peng, Y & Ollier, W 2022, ' COVID-19 Vaccination and Diabetes Mellitus: How Much Has It Made a Difference to Outcomes Following Confirmed COVID-19 Infection? ', Diabetes Therapy, pp. 1-12 . https://doi.org/10.1007/s13300-022-01338-5
Introduction: Since early 2020 the whole world has been challenged by the SARS-CoV-2 virus (COVID-19), its successive variants and the associated pandemic caused. We have previously shown that for people living with type 2 diabetes (T2DM), the risk o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b7647cebb2d707d89fc295e2119c982
https://doi.org/10.1007/s13300-022-01338-5
https://doi.org/10.1007/s13300-022-01338-5
Autor:
Giulia Maria Piperno, Asma Naseem, Giulia Silvestrelli, Roberto Amadio, Nicoletta Caronni, Karla Evelia Cervantes-Luevano, Nalan Liv, Judith Klumperman, Andrea Colliva, Hashim Ali, Francesca Graziano, Philippe Benaroch, Hans Haecker, Richard N. Hanna, Federica Benvenuti
Publikováno v:
JCI Insight, Vol 5, Iss 17 (2020)
Dysregulated sensing of self–nucleic acid is a leading cause of autoimmunity in multifactorial and monogenic diseases. Mutations in Wiskott-Aldrich syndrome protein (WASp), a key regulator of cytoskeletal dynamics in immune cells, cause autoimmune
Externí odkaz:
https://doaj.org/article/61132181a0f44b3abc254bbae0684a5e
Autor:
Sadaf Jahan, Shouvik Mukherjee, Shaheen Ali, Urvashi Bhardwaj, Ranjay Kumar Choudhary, Santhanaraj Balakrishnan, Asma Naseem, Shabir Ahmad Mir, Saeed Banawas, Mohammed Alaidarous, Hadeel Alyenbaawi, Danish Iqbal, Arif Jamal Siddiqui
Publikováno v:
Cells, Vol 11, Iss 3, p 490 (2022)
Cancer is one of the leading diseases, causing deaths worldwide. Nearly 10 million deaths were reported in 2020 due to cancer alone. Several factors are involved in cancer progressions, such as lifestyle and genetic characteristics. According to a re
Externí odkaz:
https://doaj.org/article/b64faf4ef32e4ae2a0831208866d5587
Autor:
Heald, Adrian H.1,2 (AUTHOR) adrian.heald@manchester.ac.uk, Jenkins, David A.3,4 (AUTHOR), Williams, Richard3,4,5 (AUTHOR), Mudaliar, Rajshekhar N.2 (AUTHOR), Khan, Amber2 (AUTHOR), Syed, Akheel1,2 (AUTHOR), Sattar, Naveed6 (AUTHOR), Khunti, Kamlesh7 (AUTHOR), Naseem, Asma2 (AUTHOR), Bowden-Davies, Kelly A.8 (AUTHOR), Gibson, J. Martin1,2 (AUTHOR), Ollier, William9 (AUTHOR)
Publikováno v:
Diabetes Therapy. Dec2023, Vol. 14 Issue 12, p2043-2044. 2p.