QPGx‐CARES: Qatar pharmacogenetics clinical applications and research enhancement strategies

Autor: Rania Abdel‐latif, Radja Badji, Shaban Mohammed, Wadha Al‐Muftah, Hamdi Mbarek, Dima Darwish, Duha Assaf, Daoud Al‐Badriyeh, Hazem Elewa, Nahla Afifi, Naseer Ahmad Masoodi, Amr Salah Omar, Jassim Al Suwaidi, Salha Bujassoum, Moza Al Hail, Said I. Ismail, Asma Althani

Publikováno v: Clinical and Translational Science, Vol 17, Iss 6, Pp n/a-n/a (2024)

Abstract Pharmacogenetic (PGx)‐informed medication prescription is a cutting‐edge genomic application in contemporary medicine, offering the potential to overcome the conventional “trial‐and‐error” approach in drug prescription. The abili

Externí odkaz: https://doaj.org/article/e6b2cd6df26f43e889a40c80373d678b

Qatar genome: Insights on genomics from the Middle East

Autor: Hamdi, Mbarek, Geethanjali, Devadoss Gandhi, Senthil, Selvaraj, Wadha, Al-Muftah, Radja, Badji, Yasser, Al-Sarraj, Chadi, Saad, Dima, Darwish, Muhammad, Alvi, Tasnim, Fadl, Heba, Yasin, Fatima, Alkuwari, Rozaimi, Razali, Waleed, Aamer, Fatemeh, Abbaszadeh, Ikhlak, Ahmed, Younes, Mokrab, Karsten, Suhre, Omar, Albagha, Khalid, Fakhro, Ramin, Badii, Said I, Ismail, Asma, Althani

Publikováno v: Human mutationREFERENCES. 43(4)

Despite recent biomedical breakthroughs and large genomic studies growing momentum, the Middle Eastern population, home to over 400 million people, is underrepresented in the human genome variation databases. Here we describe insights from Phase 1 of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f7cfb01e5d209e148487863e48da967
https://pubmed.ncbi.nlm.nih.gov/35112413

Robust prognostic signatures derived from proteomic panel profiling of plasma from patients with severe COVID-19 complications

Autor: Julie Decock, Shahd Ibrahim, Mohammed Al-Maadheedh, Heba Al-Siddiqi, Houari Abdesselem, Ali Ait Hssain, Walaa Saeed, Muna Al Maslamani, Hashim Alhussain, Vidya Mohamed-Ali, Waseem Samsam, Fares Al-Ejeh, Ilham Bensmail, Reham Aly, Abdulaziz Farooq, Khalid Ouararhni, Abdullatif Al Khal, Maryam Ali Al-Nesf, Saad Al-Kaabi, Alexandra Butler, Ali S. Omrani, Almurtada Razok, Asma Althani, Jassim Al-Suwaidi, Sara Mohammed, Mohamad Khatib

COVID-19 complications present a huge burden on healthcare systems and warrant a predictive risk model for disease severity of SARS-CoV-2 infection to enable early intervention, prospective decision-making and triaging of patients. We profiled plasma

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7509280786218b41a7b804cfc52236da
https://doi.org/10.21203/rs.3.rs-126482/v1

Poking COVID-19: Insights on Genomic Constraints among Immune-Related Genes between Qatari and Italian Populations

Autor: Isabella Quinti, Wadha Al-Muftah, Chadi Saad, Azza AlTawashi, Salvino Salvaggio, Said I. Ismail, Hamdi Mbarek, Dario Cocciadiferro, Yasser Al Sarraj, Massimo Mezzavilla, Giuseppe Novelli, Massimiliano Cocca, Asma AlThani, Antonio Novelli

Publikováno v: Genes; Volume 12; Issue 11; Pages: 1842
Genes
Genes, Vol 12, Iss 1842, p 1842 (2021)

Host genomic information, specifically genomic variations, may characterize susceptibility to disease and identify people with a higher risk of harm, leading to better targeting of care and vaccination. Italy was the epicentre for the spread of COVID

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4290a49353ac869c3d2f549a46fbfed
https://doi.org/10.3390/genes12111842

Nanotubes impregnated human olfactory bulb neural stem cells promote neuronal differentiation in Trimethyltin-induced neurodegeneration rat model

Autor: Hany E. Marei, Ahmed A. Elnegiry, Ahmed Abd-Elmaksoud, Carlo Cenciarelli, Amany Farag, Shymaa Rezk, Anwarul Hasan, Adel Zaghloul, Asma Althani, Zeinab Shouman, Nahla Afifi, Samah Lashen

Publikováno v: Journal of cellular physiology (Online) 232 (2017): 3586–3597. doi:10.1002/jcp.25826
info:cnr-pdr/source/autori:Hany E. Marei1 | AA Elnegiry2 | A Zaghloul3 | Asma Althani4 | Nahla Afifi5 | A Abd-Elmaksoud6 | Amany Farag6 | Samah Lashen6 | S Rezk6 | Z Shouman6 | Carlo Cenciarelli7 | Anwarul Hasan8,9,10/titolo:Nanotubes impregnated human olfactory bulb neural stem cells promote neuronal differentiation in trimethyltin-induced neurodegeneration rat model/doi:10.1002%2Fjcp.25826/rivista:Journal of cellular physiology (Online)/anno:2017/pagina_da:3586/pagina_a:3597/intervallo_pagine:3586–3597/volume:232

Neural stem cells (NSCs) are multipotent self-renewing cells that could be used in cellular-based therapy for a wide variety of neurodegenerative diseases including Alzheimer's diseases (AD), Parkinson's disease (PD), amyotrophic lateral sclerosis (A

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe8fee292d5f362ca036c68757d266f0
https://doi.org/10.1002/jcp.25826