Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Asma Achek"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract In vivo fluorescent imaging represents a potent means for real-time probe quantification, facilitating insights into disease pathophysiology and therapeutic responses. Nonetheless, accurate signal quantification remains challenging due to in
Externí odkaz:
https://doaj.org/article/5090790d1995473fba36a9611fcdc0e0
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 21, Iss , Pp 4825-4835 (2023)
Anomalous NLRP3 inflammasome responses have been linked to multiple health issues, including but not limited to atherosclerosis, diabetes, metabolic syndrome, cardiovascular disease, and neurodegenerative disease. Thus, targeting NLRP3 and modulating
Externí odkaz:
https://doaj.org/article/a6ac73ff98604b5abc07db3e89ebdf38
Autor:
Hyuk-Kwon Kwon, Mahesh Chandra Patra, Hyeon-Jun Shin, Xiangai Gui, Asma Achek, Suresh Panneerselvam, Dong-Jin Kim, Suk-Jong Song, Riwon Hong, Kyoung Soo Kim, Yang Gyun Kim, Francis Y. Lee, Dae-Hyun Hahm, Sang Ho Lee, Sangdun Choi
Publikováno v:
Experimental and Molecular Medicine, Vol 51, Iss 4, Pp 1-19 (2019)
Inflammation: A decoy peptide treats arthritis and sepsis in mice A newly discovered peptide drug that disrupts signaling through a critical immune pathway could offer a new treatment for inflammatory diseases. Sangdun Choi from Ajou University in Su
Externí odkaz:
https://doaj.org/article/d6e0d5885d2f46d4af80b5803f5e237b
Autor:
Asma Achek, Hyuk-Kwon Kwon, Mahesh Chandra Patra, Masaud Shah, Riwon Hong, Wang Hee Lee, Wook-Young Baek, Yang Seon Choi, Gi-Young Kim, Thuong L.H. Pham, Chang-Hee Suh, Wook Kim, Dae-Hyun Hahm, Sangdun Choi
Publikováno v:
EBioMedicine, Vol 52, Iss , Pp - (2020)
Background: TLRs are some of the actively pursued drug-targets in immune disorders. Owing to a recent surge in the cognizance of TLR structural biology and signalling pathways, numerous therapeutic modulators, ranging from low-molecular-weight organi
Externí odkaz:
https://doaj.org/article/42f0b77586b34ce7baf4cee728f32fe3
Autor:
Maylis Boitet, Hyeju Eun, Asma Achek, Virgínia Carla de Almeida Falcão, Vincent Delorme, Regis Grailhe
Publikováno v:
ACS Sensors. 7:2556-2566
Luminometer and imaging systems are used to detect and quantify low light produced by a broad range of bioluminescent proteins. Despite their everyday use in research, such instruments are costly and lack the flexibility to accommodate the variety of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::979193d011539fb4bdcfac3d7782e82d
https://doi.org/10.1021/acssensors.2c00457
https://doi.org/10.1021/acssensors.2c00457
Autor:
Mahesh Chandra Patra, Asma Achek, Gi-Young Kim, Suresh Panneerselvam, Hyeon-Jun Shin, Wook-Yong Baek, Wang Hee Lee, June Sung, Uisuk Jeong, Eun-Young Cho, Wook Kim, Eunha Kim, Chang-Hee Suh, Sangdun Choi
Publikováno v:
Cells, Vol 9, Iss 7, p 1648 (2020)
Toll-like receptors (TLRs) play a fundamental role in the inflammatory response against invading pathogens. However, the dysregulation of TLR-signaling pathways is implicated in several autoimmune/inflammatory diseases. Here, we show that a novel sma
Externí odkaz:
https://doaj.org/article/33e9656aa916485aa0c12a10788cb9cc
Autor:
Dong-Jin Kim, Masaud Shah, Hyeon Jun Shin, Tae Hyeon Yoo, Sang-Ho Lee, Asma Achek, Byeong Sung Lee, Moon Suk Kim, Sangdun Choi, Hyuk-Kwon Kwon, Ji Young Seo, Gui Xiangai, Eun Young Cho
Publikováno v:
Journal of Medicinal Chemistry. 62:6495-6511
A mounting evidence exists for the despicable role of the aberrant immune response in the pathogenesis of rheumatoid arthritis (RA), where toll-like receptor 4 (TLR4) can activate synovial fibroblasts that lead to the chronic inflammation and joint d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9144068e111edc60abc16d09d29c1a7e
https://doi.org/10.1021/acs.jmedchem.9b00061
https://doi.org/10.1021/acs.jmedchem.9b00061
Autor:
Yang Gyun Kim, Mahesh Chandra Patra, Gui Xiangai, Riwon Hong, Suresh Panneerselvam, Kyoung Soo Kim, Sangdun Choi, Asma Achek, Dae-Hyun Hahm, Sang-Ho Lee, Hyeon-Jun Shin, Hyuk-Kwon Kwon, Suk-Jong Song, Francis Y. Lee, Dong-Jin Kim
Publikováno v:
Experimental & Molecular Medicine
Experimental and Molecular Medicine, Vol 51, Iss 4, Pp 1-19 (2019)
Experimental and Molecular Medicine, Vol 51, Iss 4, Pp 1-19 (2019)
Toll-like receptors (TLRs) recognize pathogen/damage-associated molecular patterns and initiate inflammatory signaling cascades. Occasionally, overexpression of TLRs leads to the onset of numerous inflammatory diseases, necessitating the development
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da8c7c86ae3557063c5cd4981f59bb98
https://doi.org/10.1038/s12276-019-0244-0
https://doi.org/10.1038/s12276-019-0244-0
Autor:
Suresh Panneerselvam, Sangdun Choi, Eunha Kim, Uisuk Jeong, Wook Kim, Hyeon-Jun Shin, Wook-Yong Baek, Eun Young Cho, June Sung, Gi-Young Kim, Asma Achek, Chang-Hee Suh, Mahesh Chandra Patra, Wang Hee Lee
Publikováno v:
Cells, Vol 9, Iss 1648, p 1648 (2020)
Cells
Volume 9
Issue 7
Cells
Volume 9
Issue 7
Toll-like receptors (TLRs) play a fundamental role in the inflammatory response against invading pathogens. However, the dysregulation of TLR-signaling pathways is implicated in several autoimmune/inflammatory diseases. Here, we show that a novel sma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::427b68a7523c35ff95dd56b7f73545b2
https://www.mdpi.com/2073-4409/9/7/1648
https://www.mdpi.com/2073-4409/9/7/1648
Autor:
Seolhee Park, Masaud Shah, Hey-Young Cho, Sangdun Choi, Byugsung Lee, Asma Achek, Hyuk-Kwon Kwon, Hyeon-Jun Shin, Muhammad Anwar, Tae Hyeon Yoo
Publikováno v:
Biomaterials. 126:49-60
Negative regulation of Toll-like receptor-4 (TLR4) is anticipated to control the pathogen-induced exaggerated immune response. However, effective TLR4 antagonists with scarce off-target effects are yet to be developed. To fill this void, we sought to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bdd793295312ec5a12c01e5935ce554
https://doi.org/10.1016/j.biomaterials.2017.02.023
https://doi.org/10.1016/j.biomaterials.2017.02.023