Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Asma, Hatoum"'
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Recent research has identified multiple immune systems that bacteria use to protect themselves from viral infections. However, little is known about the mechanisms by which these systems horizontally spread, especially among bacterial pathog
Externí odkaz:
https://doaj.org/article/8f3099295e92416e8604764a1f54aa54
Autor:
Mohammadreza Paraan, Mohamed Nasef, Lucy Chou-Zheng, Sarah A Khweis, Allyn J Schoeffler, Asma Hatoum-Aslan, Scott M Stagg, Jack A Dunkle
Publikováno v:
PLoS ONE, Vol 18, Iss 6, p e0287461 (2023)
Type III CRISPR-Cas systems employ multiprotein effector complexes bound to small CRISPR RNAs (crRNAs) to detect foreign RNA transcripts and elicit a complex immune response that leads to the destruction of invading RNA and DNA. Type III systems are
Externí odkaz:
https://doaj.org/article/4c4628a29f774aeb9368b0d71c32ec96
Autor:
Lucy Chou-Zheng, Asma Hatoum-Aslan
Publikováno v:
eLife, Vol 11 (2022)
CRISPR-Cas systems are a family of adaptive immune systems that use small CRISPR RNAs (crRNAs) and CRISPR-associated (Cas) nucleases to protect prokaryotes from invading plasmids and viruses (i.e., phages). Type III systems launch a multilayered immu
Externí odkaz:
https://doaj.org/article/1b4ffecd2a1d4477acd9d42a62cff59f
Autor:
Lucy Chou-Zheng, Asma Hatoum-Aslan
Publikováno v:
eLife, Vol 8 (2019)
CRISPR-Cas systems provide sequence-specific immunity against phages and mobile genetic elements using CRISPR-associated nucleases guided by short CRISPR RNAs (crRNAs). Type III systems exhibit a robust immune response that can lead to the extinction
Externí odkaz:
https://doaj.org/article/b01c4303d5e04b5ca9513e9bbc52f829
Publikováno v:
bioRxiv
Bacterial viruses (phages) and the immune systems targeted against them significantly impact bacterial survival, evolution, and the emergence of pathogenic strains. While recent research has made spectacular strides towards discovering and validating
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a452d2a0b998c6a3b8634e7633acf847
https://doi.org/10.1101/2023.03.17.533233
https://doi.org/10.1101/2023.03.17.533233
Autor:
Asma Hatoum-Aslan
Publikováno v:
Trends Microbiol
The phages that infect Staphylococcus species are dominant residents of the skin microbiome that play critical roles in health and disease. While temperate phages, which can integrate into the host genome, have the potential to promote staphylococcal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72c47f1c25831472c1eacb5e8a693e15
https://doi.org/10.1016/j.tim.2021.04.008
https://doi.org/10.1016/j.tim.2021.04.008
Publikováno v:
Science Advances. 8
Staphylococcus epidermidis is an opportunistic pathogen of the human skin, often associated with infections of implanted medical devices. Staphylococcal picoviruses are a group of strictly lytic, short-tailed bacteriophages with compact genomes that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a8c0e9e698a9ebb5b5e5b972ab2176c5
https://doi.org/10.1126/sciadv.ade0459
https://doi.org/10.1126/sciadv.ade0459
Publikováno v:
Science advances. 8(48)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a79913d326d8fa911943e306b4e5c939
https://pubmed.ncbi.nlm.nih.gov/36449623
https://pubmed.ncbi.nlm.nih.gov/36449623
Autor:
Tori A. Boyle, Asma Hatoum-Aslan
Publikováno v:
Cell hostmicrobe. 30(11)
In this issue of Cell Hostamp; Microbe, Millman et al. use bioinformatic and genetic approaches to discover 21 novel antiviral immune systems in prokaryotes. Remarkably, many of these systems bear homology to components of the human innate immune sys
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d660613c7e0815e8dc42835ed10c9afa
https://pubmed.ncbi.nlm.nih.gov/36356563
https://pubmed.ncbi.nlm.nih.gov/36356563