Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Aslina Pahrudin Arrozi"'
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Tau, a family of microtubule-associated proteins, forms abnormal intracellular inclusions, so-called tau pathology, in a range of neurodegenerative diseases collectively known as tauopathies. The rTg4510 mouse model is a well-characterized b
Externí odkaz:
https://doaj.org/article/dca4a4546b4540bb90b7036201aad0c5
Autor:
Aslina Pahrudin Arrozi, Siti Nur Syazwani Shukri, Nuraqila Mohd Murshid, Ahmad Baihaqi Ahmad Shahzalli, Wan Zurinah Wan Ngah, Hanafi Ahmad Damanhuri, Suzana Makpol
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 16 (2022)
The amyloid precursor protein (APP) processing pathway was altered in Alzheimer’s disease (AD) and contributed to abnormal amyloid-beta (Aβ) production, which forms insoluble interneuron protein aggregates known as amyloid plaques in the brain. Ta
Externí odkaz:
https://doaj.org/article/de00623d41bb45dcaf5104e66f3dcb26
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Increased amyloid-beta (Aβ) and amyloid precursor protein (APP) in the brains of Alzheimer’s disease (AD) patients are common pathological hallmarks mediating the disease progression. Growing evidence also suggests that mitochondrial abnormalities
Externí odkaz:
https://doaj.org/article/9db1ebba1c744ebdad308529e21ba89b
Autor:
Aslina Pahrudin Arrozi, Zulzikry Hafiz Abu Bakar, Hiroyasu Taguchi, Daijiro Yanagisawa, Ikuo Tooyama
Publikováno v:
Molecules, Vol 26, Iss 17, p 5342 (2021)
Thioredoxin-interacting protein (TXNIP) is involved in multiple disease-associated functions related to oxidative stress, especially by inhibiting the anti-oxidant- and thiol-reducing activity of thioredoxin (TXN). Shiga-Y5 (SY5), a fluorine-19 magne
Externí odkaz:
https://doaj.org/article/a8fefd9fee2e43c99dc32028d1662037
Autor:
Asuka Matsuzaki Tada, Hamizah Shahirah Hamezah, Aslina Pahrudin Arrozi, Zulzikry Hafiz Abu Bakar, Daijiro Yanagisawa, Ikuo Tooyama
Publikováno v:
Journal of Alzheimer's Disease. 89(3):835-848
Background:Tripeptide Met-Lys-Pro (MKP), a component of casein hydrolysates, has effective angiotensin-converting enzyme (ACE) inhibitory activity. Brain angiotensin II enzyme activates the NADPH oxidase complex via angiotensin II receptor type 1 (AT
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::972a807311bb84303e8e4dd92b9f603c
http://hdl.handle.net/10422/00013448
http://hdl.handle.net/10422/00013448
Autor:
Aslina Pahrudin Arrozi, Yoshio Hashizume, Daita Kaneda, Tomoko Kato, Ikuo Tooyama, Hiroyasu Akatsu, Daijiro Yanagisawa
Publikováno v:
Journal of Alzheimer's Disease Reports
Background:Emerging evidence indicates that the misfolded tau protein can propagate aggregates between cells in a prion-like manner. This prion activity has been typically studied in brain extracts of patients with Alzheimer’s disease (AD), but not
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad274f1194af961f9ec69d7727c40f83
https://doi.org/10.3233/adr-210298
https://doi.org/10.3233/adr-210298
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Frontiers in Pharmacology
Frontiers in Pharmacology
Increased amyloid-beta (Aβ) and amyloid precursor protein (APP) in the brains of Alzheimer’s disease (AD) patients are common pathological hallmarks mediating the disease progression. Growing evidence also suggests that mitochondrial abnormalities
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc51f5913e4333e431f7e1f47da09bf2
https://www.frontiersin.org/articles/10.3389/fphar.2021.698833/full
https://www.frontiersin.org/articles/10.3389/fphar.2021.698833/full
Autor:
Aslina Pahrudin Arrozi, Suzana Makpol, Mohd Hanafi Ahmad Damanhuri, Siti Nur Syazwani Shukri, Yasmin Anum Mohd Yusof, Faizul Jaafar, Wan Zurinah Wan Ngah
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
Vitamin E acts as an antioxidant and reduces the level of reactive oxygen species (ROS) in Alzheimer’s disease (AD). Alpha-tocopherol (ATF) is the most widely studied form of vitamin E besides gamma-tocopherol (GTF) which also shows beneficial effe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e613a0dec2c8eb1723bdd98a940bb5b
https://doi.org/10.1038/s41598-020-65570-4
https://doi.org/10.1038/s41598-020-65570-4
Autor:
Suzana Makpol, Siti Nur Syazwani Shukri, Mohd Hanafi Ahmad Damanhuri, Yasmin Anum Mohd Yusof, Aslina Pahrudin Arrozi, Wan Zurinah Wan Ngah
Publikováno v:
Applied biochemistry and biotechnology. 183(3)
Neuroblastoma cell lines such as SH-SY5Y are the most frequently utilized models in neurodegenerative research, and their use has advanced the understanding of the pathology of neurodegeneration over the past few decades. In Alzheimer’s disease (AD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec8bad6d519079e4b26a49df92f8caf1
https://pubmed.ncbi.nlm.nih.gov/28417423
https://pubmed.ncbi.nlm.nih.gov/28417423