Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Aslihan Ugun-Klusek"'
Publikováno v:
npj Regenerative Medicine, Vol 6, Iss 1, Pp 1-7 (2021)
Abstract Exercise is a non-pharmacological intervention that can enhance bone regeneration and improve the management of bone conditions like osteoporosis or metastatic bone cancer. Therefore, it is gaining increasing importance in an emerging area o
Externí odkaz:
https://doaj.org/article/228cbdb7811546228228ea7a661c635c
Autor:
Carmen Herranz, Francesca Mateo, Alexandra Baiges, Gorka Ruiz de Garibay, Alexandra Junza, Simon R Johnson, Suzanne Miller, Nadia García, Jordi Capellades, Antonio Gómez, August Vidal, Luis Palomero, Roderic Espín, Ana I Extremera, Eline Blommaert, Eva Revilla‐López, Berta Saez, Susana Gómez‐Ollés, Julio Ancochea, Claudia Valenzuela, Tamara Alonso, Piedad Ussetti, Rosalía Laporta, Antoni Xaubet, José A Rodríguez‐Portal, Ana Montes‐Worboys, Carlos Machahua, Jaume Bordas, Javier A Menendez, Josep M Cruzado, Roser Guiteras, Christophe Bontoux, Concettina La Motta, Aleix Noguera‐Castells, Mario Mancino, Enrique Lastra, Raúl Rigo‐Bonnin, Jose C Perales, Francesc Viñals, Alvaro Lahiguera, Xiaohu Zhang, Daniel Cuadras, Coline H M vanMoorsel, Joanne J van derVis, Marian J R Quanjel, Harilaos Filippakis, Razq Hakem, Chiara Gorrini, Marc Ferrer, Aslihan Ugun‐Klusek, Ellen Billett, Elżbieta Radzikowska, Álvaro Casanova, María Molina‐Molina, Antonio Roman, Oscar Yanes, Miquel A Pujana
Publikováno v:
EMBO Molecular Medicine, Vol 13, Iss 9, Pp n/a-n/a (2021)
Abstract Inhibition of mTOR is the standard of care for lymphangioleiomyomatosis (LAM). However, this therapy has variable tolerability and some patients show progressive decline of lung function despite treatment. LAM diagnosis and monitoring can al
Externí odkaz:
https://doaj.org/article/51f572bcdff644bcab3c3cc538fd0d47
Autor:
Aslihan Ugun-Klusek, Theodosis S. Theodosi, Julia C. Fitzgerald, Florence Burté, Christoph Ufer, David J. Boocock, Patrick Yu-Wai-Man, Lynn Bedford, E. Ellen Billett
Publikováno v:
Redox Biology, Vol 20, Iss , Pp 167-181 (2019)
Monoamine oxidases (MAOs) are located on the outer mitochondrial membrane and are drug targets for the treatment of neurological disorders. MAOs control the levels of neurotransmitters in the brain via oxidative deamination and contribute to reactive
Externí odkaz:
https://doaj.org/article/6433d8e6f4db46e580b30b0875bd1505
Autor:
Christine Bus, Laimdota Zizmare, Marita Feldkaemper, Sven Geisler, Maria Zarani, Anna Schaedler, Franziska Klose, Jakob Admard, Craig J. Mageean, Giuseppe Arena, Petra Fallier-Becker, Aslihan Ugun-Klusek, Klaudia K. Maruszczak, Konstantina Kapolou, Benjamin Schmid, Doron Rapaport, Marius Ueffing, Nicolas Casadei, Rejko Krüger, Thomas Gasser, Daniela M. Vogt Weisenhorn, Philipp J. Kahle, Christoph Trautwein, Christian J. Gloeckner, Julia C. Fitzgerald
Publikováno v:
iScience, Vol 23, Iss 12, Pp 101797- (2020)
Summary: PINK1 loss-of-function mutations cause early onset Parkinson disease. PINK1-Parkin mediated mitophagy has been well studied, but the relevance of the endogenous process in the brain is debated.Here, the absence of PINK1 in human dopaminergic
Externí odkaz:
https://doaj.org/article/2face2d98c5c4f1ab1e9729b358fa6c2
Publikováno v:
Biology, Vol 10, Iss 8, p 723 (2021)
Hypoxia is a condition characterized by insufficient tissue oxygenation, which results in impaired oxidative energy production. A reduction in cellular oxygen levels induces the stabilization of hypoxia inducible factor α (HIF-1α), master regulator
Externí odkaz:
https://doaj.org/article/348b17a029b54118a02c34d8cff4fa11
Autor:
Tanya M Monaghan, Aslihan Ugun-Klusek, Mattea Finelli, Pratik Gurnani, Lisa Chakrabarti, Dina Kao, Cameron Alexander, Christos Polytarchou
Publikováno v:
Gut. :gutjnl-2022
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::db0d7024d673f27e5a4e98892d311dfc
https://doi.org/10.1136/gutjnl-2022-327301
https://doi.org/10.1136/gutjnl-2022-327301
Publikováno v:
Biology, Vol 10, Iss 723, p 723 (2021)
Biology
Biology
Simple Summary Parkinson’s disease is a neurodegenerative disorder characterized by the death of a specific subset of dopamine-producing neurons. This triggers problems with movement as dopamine is key in regulating motor control. To date, availabl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd4e282938285ad5dbec86bd0d378ecd
https://www.mdpi.com/2079-7737/10/8/723
https://www.mdpi.com/2079-7737/10/8/723
Autor:
Patrick Yu-Wai-Man, Christoph Ufer, Lynn Bedford, David J. Boocock, Theodosis S. Theodosi, Aslihan Ugun-Klusek, Julia C. Fitzgerald, E. Ellen Billett, Florence Burté
Publikováno v:
Redox Biology, Vol 20, Iss, Pp 167-181 (2019)
Redox Biology 20, 167-181 (2019). doi:10.1016/j.redox.2018.10.003
Redox Biology
Redox Biology 20, 167-181 (2019). doi:10.1016/j.redox.2018.10.003
Redox Biology
Monoamine oxidases (MAOs) are located on the outer mitochondrial membrane and are drug targets for the treatment of neurological disorders. MAOs control the levels of neurotransmitters in the brain via oxidative deamination and contribute to reactive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cee6c7f7a07ce2d77e3885777776be6e
http://www.sciencedirect.com/science/article/pii/S2213231718307341
http://www.sciencedirect.com/science/article/pii/S2213231718307341
Autor:
Coline H M van Moorsel, Ana Montes-Worboys, Razq Hakem, E. Ellen Billett, Carmen Herranz, Eline Blommaert, Oscar Yanes, Antonio Roman, Julio Ancochea, Álvaro Casanova, Raúl Rigo-Bonnin, Harilaos Filippakis, Berta Saez, August Vidal, Alexandra Baiges, Antoni Xaubet, Suzanne Miller, Antonio Gomez, Roderic Espín, Joanne J van der Vis, José A Rodríguez-Portal, Chiara Gorrini, Jaume Bordas, Marian J R Quanjel, Aleix Noguera-Castells, Luis Palomero, Eva Revilla-López, Josep M. Cruzado, Xiaohu Zhang, Enrique Lastra, Nadia García, Elżbieta Radzikowska, Marc Ferrer, Simon R. Johnson, Christophe Bontoux, Maria Molina-Molina, Alexandra Junza, Javier A. Menendez, Ana I. Extremera, Piedad Ussetti, Rosalía Laporta, Álvaro Lahiguera, Miquel Angel Pujana, Susana Gómez-Ollés, Daniel Cuadras, Mario Mancino, Claudia Valenzuela, Tamara Alonso, Jose C. Perales, Francesca Mateo, Francesc Viñals, Aslihan Ugun-Klusek, Gorka Ruiz de Garibay, Roser Guiteras, Jordi Capellades, Concettina La Motta, Carlos Machahua
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
EMBO Molecular Medicine
r-FSJD. Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
Scientia
DDFV. Repositorio Institucional de la Universidad Francisco de Vitoria
Dipòsit Digital de la UB
Universidad de Barcelona
EMBO Molecular Medicine, Vol 13, Iss 9, Pp n/a-n/a (2021)
instname
EMBO Molecular Medicine
r-FSJD. Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
Scientia
DDFV. Repositorio Institucional de la Universidad Francisco de Vitoria
Dipòsit Digital de la UB
Universidad de Barcelona
EMBO Molecular Medicine, Vol 13, Iss 9, Pp n/a-n/a (2021)
Inhibition of mTOR is the standard of care for lymphangioleiomyomatosis (LAM). However, this therapy has variable tolerability and some patients show progressive decline of lung function despite treatment. LAM diagnosis and monitoring can also be cha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3528695e98889a787bd38a10b1b3e32
http://hdl.handle.net/10261/265901
http://hdl.handle.net/10261/265901
Autor:
T. Gasser, Betül Uysal, Garcia A, Nicolas Casadei, Anna Schaedler, Katharina Zittlau, Britta Brügger, Philipp J. Kahle, Sven Geisler, Petra Fallier-Becker, Aslihan Ugun-Klusek, Marita Feldkaemper, Gerard J.M. Martens, L. Schwarz, Boris Macek, Christine Bus, Vogt Weisenhorn Dm, Jos F. Brouwers, Henner Koch, Wolfgang Wurst, Julia C. Fitzgerald, Rejko Krüger, Schmidt B, Klaudia K. Maruszczak, Hector Flores-Romero, Doron Rapaport, Zarani M
Mitochondrial dysfunction contributes to the pathogenesis of Parkinson’s disease but it is not clear why inherent mitochondrial defects lead specifically to the death of dopaminergic neurons of the mid brain. PINK1 is mitochondrial kinase andPINK1m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9dfc420177e476237e9aa77ab8e0dd1
https://doi.org/10.1101/814343
https://doi.org/10.1101/814343