Zobrazeno 1 - 10
of 92
pro vyhledávání: '"Aslan A Kubatiev"'
Autor:
Sergey A. Menzikov, Danila M. Zaichenko, Aleksey A. Moskovtsev, Sergey G. Morozov, Aslan A. Kubatiev
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
γ-Aminobutyric acid type A receptors (GABAARs) are members of the pentameric ligand-gated ion channel (pLGIC) family, which are widespread throughout the invertebrate and vertebrate central nervous system. GABAARs are engaged in short-term changes o
Externí odkaz:
https://doaj.org/article/5d96546cf7854bf0a324020fdab33eb0
Autor:
Alexander Vladimirovich Ivanov, Marina Yurievna Maksimova, Ksenya Alexandrovna Nikiforova, Fatima Ramazanovna Ochtova, Ekaterina Taymurazovna Suanova, Valery Vasil’evich Alexandrin, Maria Petrovna Kruglova, Mikhail Aleksanrovich Piradov, Aslan Amirkhanovich Kubatiev
Publikováno v:
The Egyptian Journal of Neurology, Psychiatry and Neurosurgery, Vol 58, Iss 1, Pp 1-8 (2022)
Abstract Objective Glutathione (GSH) is a major intracellular thiol-containing antioxidant. We tried to determine whether blood plasma GSH level is a marker for the severity of the two subtypes of acute stroke (large-artery atherosclerosis, LA and ca
Externí odkaz:
https://doaj.org/article/1236a57aa23044ebb10d6a361f37b6ea
Autor:
Alexander Gennadievich Filippov, Valery Vasil’evich Alexandrin, Alexander Vladimirovich Ivanov, Alexander Alexandrovich Paltsyn, Nadezhda Borisovna Sviridkina, Edward Danielevich Virus, Polina Olegovna Bulgakova, Joanna Petrovna Burmiy, Aslan Amirkhanovich Kubatiev
Publikováno v:
Journal of Functional Biomaterials, Vol 14, Iss 7, p 348 (2023)
Platinum nanoparticles (nPts) have neuroprotective/antioxidant properties, but the mechanisms of their action in cerebrovascular disease remain unclear. We investigated the brain bioavailability of nPts and their effects on brain damage, cerebral blo
Externí odkaz:
https://doaj.org/article/9d4a425fe56e45e6b865d662fd9bac40
Autor:
Alexander Vladimirovich Ivanov, Mikhail Aleksandrovich Popov, Arkady Andreevich Metelkin, Valery Vasil’evich Aleksandrin, Evgeniy Gennad’evich Agafonov, Maria Petrovna Kruglova, Ekaterina Vladimirovna Silina, Victor Aleksandrovich Stupin, Ruslan Andreevich Maslennikov, Aslan Amirkhanovich Kubatiev
Publikováno v:
Metabolites, Vol 13, Iss 6, p 743 (2023)
Coronary artery disease (CAD) and the coronary artery bypass graft (CABG) are associated with a decreased blood glutathione (bGSH) level. Since GSH metabolism is closely related to other aminothiols (homocysteine and cysteine) and glucose, the aim of
Externí odkaz:
https://doaj.org/article/3ff16147c8bf4b149f99f7a9ea18e115
Autor:
Natalia R. Onishchenko, Alexey A. Moskovtsev, Maria K. Kobanenko, Daria S. Tretiakova, Anna S. Alekseeva, Dmitry V. Kolesov, Anna A. Mikryukova, Ivan A. Boldyrev, Marina R. Kapkaeva, Olga N. Shcheglovitova, Nicolai V. Bovin, Aslan A. Kubatiev, Olga V. Tikhonova, Elena L. Vodovozova
Publikováno v:
Pharmaceutics, Vol 15, Iss 6, p 1754 (2023)
Previously, we showed in the human umbilical vein endothelial cells (HUVECs) model that a liposome formulation of melphalan lipophilic prodrug (MlphDG) decorated with selectin ligand tetrasaccharide Sialyl Lewis X (SiaLeX) undergoes specific uptake b
Externí odkaz:
https://doaj.org/article/f7f68554b7634b1e86713e7a8d0e8ddb
Autor:
Marina Yurievna Maksimova, Alexander Vladimirovich Ivanov, Edward Danielevich Virus, Ksenya Alexandrovna Nikiforova, Fatima Ramazanovna Ochtova, Ekaterina Taymurazovna Suanova, Maria Petrovna Kruglova, Mikhail Aleksanrovich Piradov, Aslan Amirkhanovich Kubatiev
Publikováno v:
Redox Report, Vol 26, Iss 1, Pp 117-123 (2021)
Objective Acute brain ischemia is accompanied by a disruption of low-molecular-weight aminothiols (LMWTs) homeostasis, such as homocysteine (Hcy), cysteine (Cys), and glutathione (GSH). We investigated the redox balance of LMWTs in blood plasma and i
Externí odkaz:
https://doaj.org/article/252bc36c27dc4af1acd792a58590db85
Autor:
Alisa A. Sokolovskaya, Mikhail A. Popov, Ekaterina A. Sergeeva, Arkadiy A. Metelkin, Dmitry I. Zybin, Dmitry V. Shumakov, Aslan A. Kubatiev
Publikováno v:
Biomedicines, Vol 11, Iss 2, p 251 (2023)
Platelets are one of the main participants in vascular accidents in cases of coronary heart disease (CHD). In this study, we sought to detect platelet apoptosis in patients with coronary artery disease who underwent scheduled myocardial revasculariza
Externí odkaz:
https://doaj.org/article/2c561e34e4a34b0cba97385144285696
Autor:
Vodovozova, Natalia R. Onishchenko, Alexey A. Moskovtsev, Maria K. Kobanenko, Daria S. Tretiakova, Anna S. Alekseeva, Dmitry V. Kolesov, Anna A. Mikryukova, Ivan A. Boldyrev, Marina R. Kapkaeva, Olga N. Shcheglovitova, Nicolai V. Bovin, Aslan A. Kubatiev, Olga V. Tikhonova, Elena L.
Publikováno v:
Pharmaceutics; Volume 15; Issue 6; Pages: 1754
Previously, we showed in the human umbilical vein endothelial cells (HUVECs) model that a liposome formulation of melphalan lipophilic prodrug (MlphDG) decorated with selectin ligand tetrasaccharide Sialyl Lewis X (SiaLeX) undergoes specific uptake b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::d47820424d54a658677fa3a0e69ce0da
Autor:
Larisa V Smolyaninova, Alexandra A Shiyan, Leonid V Kapilevich, Alexander V Lopachev, Tatiana N Fedorova, Tatiana S Klementieva, Aleksey A Moskovtsev, Aslan A Kubatiev, Sergei N Orlov
Publikováno v:
PLoS ONE, Vol 14, Iss 9, p e0222767 (2019)
It was shown previously that inhibition of the ubiquitous α1 isoform of Na+,K+-ATPase by ouabain sharply affects gene expression profile via elevation of intracellular [Na+]i/[K+]i ratio. Unlike other cells, neurons are abundant in the α3 isoform o
Externí odkaz:
https://doaj.org/article/148a9b22d6e8453586b9fcbe49093f2e
Autor:
Sergey A. Menzikov, Danila M. Zaichenko, Aleksey A. Moskovtsev, Sergey G. Morozov, Aslan A. Kubatiev
Publikováno v:
International Journal of Molecular Sciences
Volume 24
Issue 3
Pages: 2764
Volume 24
Issue 3
Pages: 2764
Zinc ions (Zn2+) are concentrated in various brain regions and can act as a neuromodulator, targeting a wide spectrum of postsynaptic receptors and enzymes. Zn2+ inhibits the GABAARs, and its potency is profoundly affected by the subunit composition
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b9d68b770f8d8bfed98525eb5db86a2