Expression Quantitative Trait Loci Acting Across Multiple Tissues Are Enriched in Inherited Risk for Coronary Artery Disease

Autor: Asl, H.F., Talukdar, H.A., Kindt, A.S.D., Jain, R.K., Ermel, R., Ruusalepp, A., Nguyen, K.H., Dobrin, R., Reilly, D.F., Schunkert, H., Samani, N.J., Braenne, I., Erdmann, J., Melander, O., Qi, J., Ivert, T., Skogsberg, J., Schadt, E.E., Michoel, T., Bjorkegren, J.L.M., CARDIoGRAM Consortium (Döring, A., Meisinger, C., Meitinger, T., Peters, A., Wichmann, H.-E.)

Publikováno v: Circ. Cardiovasc. Genet. 8, 305-315 (2015)

Background— Despite recent discoveries of new genetic risk factors, the majority of risk for coronary artery disease (CAD) remains elusive. As the most proximal sensor of DNA variation, RNA abundance can help identify subpopulations of genetic vari

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eea3ec083ebd8718b595793d77ee9585
https://doi.org/10.1161/circgenetics.114.000640

Additional Candidate Genes for Human Atherosclerotic Disease Identified Through Annotation Based on Chromatin Organization

Autor: Haitjema, S., Meddens, C.A., Laan, S.W. van der, Kofink, D., Harakalova, M., Tragante, V., Asl, H.F., Setten, J. van, Brandt, M.M., Bis, J.C., O'Donnell, C., Cheng, C., Hoefer, I.E., Waltenberger, J., Biessen, E., Jukema, J.W., Doevendans, P.A.F.M., Nieuwenhuis, E.E.S., Erdmann, J., Bjorkegren, J.L.M., Pasterkamp, G., Asselbergs, F.W., Ruijter, H.M. den, Mokry, M., CHARGE Consortium, METASTROKE Grp Int Stroke Genetics

Publikováno v: Circulation-Cardiovascular genetics, 10(2). Lippincott Williams and Wilkins
Circulation : Cardiovascular Genetics, 10(2):001664. LIPPINCOTT WILLIAMS & WILKINS
Circulation: Cardiovascular Genetics, 10(2)
Circulation-cardiovascular genetics, 10(2):UNSP e001664. Lippincott Williams & Wilkins

Background— As genome-wide association efforts, such as CARDIoGRAM and METASTROKE, are ongoing to reveal susceptibility loci for their underlying disease—atherosclerotic disease—identification of candidate genes explaining the associations of t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::839cb8b2556feb8033414e4ddc14fd2e
https://hdl.handle.net/1887/95079

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