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Coupled proliferation and apoptosis maintain the rapid turnover of microglia in the adult brain

Autor: Askew, K, Li, K, Olmos-Alonso, A, Garcia-Moreno, F, Liang, Y, Richardson, P, Tipton, T, Chapman, MA, Riecken, K, Beccari, S, Sierra, A, Molnár, Z, Cragg, MS, Garaschuk, O, Perry, VH, Gomez-Nicola, D

Publikováno v: Cell Reports, Vol 18, Iss 2, Pp 391-405 (2017)
Cell Reports

Summary Microglia play key roles in brain development, homeostasis, and function, and it is widely assumed that the adult population is long lived and maintained by self-renewal. However, the precise temporal and spatial dynamics of the microglial po

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::38f624411895610945aaab118c33898e
https://eprints.soton.ac.uk/403985/

Pharmacological targeting of CSF1R inhibits microglial proliferation and prevents the progression of Alzheimer’s-like pathology

Autor: Olmos-Alonso A, St, Schetters, Sri S, Askew K, Mancuso R, Vargas-Caballero M, Holscher C, Vh, Perry, Diego Gomez-Nicola

Publikováno v: Brain
Europe PubMed Central

Microglial proliferation and activation is a hallmark of Alzheimer's disease. Olmos-Alonso et al. show that microglial proliferation in Alzheimer's disease tissue correlates with overactivation of the colony-stimulating factor 1 receptor (CSF1R) path

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::3bb3680fe062cc905dd49d59ad7d6f82
https://eprints.soton.ac.uk/385694/

Validation of a Performance Checklist for Ultrasound Guided Internal Jugular Central Lines for Use in Procedural Instruction and Assessment

Autor: Hartman, N., Wittler, M., Hiestand, B., Manthey, D., Askew, K.

Publikováno v: Hartman, N.; Wittler, M.; Hiestand, B.; Manthey, D.; & Askew, K.(2015). Validation of a Performance Checklist for Ultrasound Guided Internal Jugular Central Lines for Use in Procedural Instruction and Assessment. Western Journal of Emergency Medicine, 16(4.1). Retrieved from: http://www.escholarship.org/uc/item/376692d9

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Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::0aa90396fc2aecc931314025d5e56c7e
http://www.escholarship.org/uc/item/376692d9